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3rd Branchial Cleft Cyst
Bernadette L. Koch, MD
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Clinical Issues

          • Diagnostic Checklist

            TERMINOLOGY

            • Abbreviations

              • 3rd branchial cleft cyst (BCC)
            • Synonyms

              • 3rd branchial apparatus cyst (BAC)
            • Definitions

              • Epithelial-lined cystic remnant of 3rd branchial cleft

            IMAGING

            • General Features

              • Fluoroscopic Findings

                • CT Findings

                  • MR Findings

                    • Ultrasonographic Findings

                      • Imaging Recommendations

                        DIFFERENTIAL DIAGNOSIS

                          PATHOLOGY

                          • General Features

                            • Gross Pathologic & Surgical Features

                              • Microscopic Features

                                CLINICAL ISSUES

                                • Presentation

                                  • Demographics

                                    • Natural History & Prognosis

                                      • Treatment

                                        DIAGNOSTIC CHECKLIST

                                        • Consider

                                          Selected References

                                          1. Goff CJ et al: Current management of congenital branchial cleft cysts, sinuses, and fistulae. Curr Opin Otolaryngol Head Neck Surg. 20(6):533-9, 2012
                                          2. Bajaj Y et al: Branchial anomalies in children. Int J Pediatr Otorhinolaryngol. 75(8):1020-3, 2011
                                          3. Pahlavan S et al: Microbiology of third and fourth branchial pouch cysts. Laryngoscope. 120(3):458-62, 2010
                                          4. Thomas B et al: Revisiting imaging features and the embryologic basis of third and fourth branchial anomalies. AJNR Am J Neuroradiol. 31(4):755-60, 2010
                                          5. Joshi MJ et al: The rare third branchial cleft cyst. AJNR Am J Neuroradiol. 30(9):1804-6, 2009
                                          6. Koch BL: Cystic malformations of the neck in children. Pediatr Radiol. 35(5):463-77, 2005
                                          7. Khariwala SS et al: Cervical presentations of thymic anomalies in children. Int J Pediatr Otorhinolaryngol. 68(7):909-14, 2004
                                          8. Pereira KD et al: Management of anomalies of the third and fourth branchial pouches. Int J Pediatr Otorhinolaryngol. 68(1):43-50, 2004
                                          9. Tsai CC et al: Branchial-cleft sinus presenting with a retropharyngeal abscess for a newborn: a case report. Am J Perinatol. 20(5):227-31, 2003
                                          10. Liberman M et al: Ten years of experience with third and fourth branchial remnants. J Pediatr Surg. 37(5):685-90, 2002
                                          11. Huang RY et al: Third branchial cleft anomaly presenting as a retropharyngeal abscess. Int J Pediatr Otorhinolaryngol. 54(2-3):167-72, 2000
                                          12. Mandell DL: Head and neck anomalies related to the branchial apparatus. Otolaryngol Clin North Am. 33(6):1309-32, 2000
                                          13. Mukherji SK et al: Imaging of congenital anomalies of the branchial apparatus. Neuroimaging Clin N Am. 10(1):75-93, viii, 2000
                                          14. Nicollas R et al: Congenital cysts and fistulas of the neck. Int J Pediatr Otorhinolaryngol. 55(2):117-24, 2000
                                          15. Koeller KK et al: Congenital cystic masses of the neck: radiologic-pathologic correlation. Radiographics. 19(1):121-46; quiz 152-3, 1999
                                          16. Mouri N et al: Reappraisal of lateral cervical cysts in neonates: pyriform sinus cysts as an anatomy-based nomenclature. J Pediatr Surg. 33(7):1141-4, 1998
                                          17. Edmonds JL et al: Third branchial anomalies. Avoiding recurrences. Arch Otolaryngol Head Neck Surg. 123(4):438-41, 1997
                                          18. Kelley DJ et al: Cervicomediastinal thymic cysts. Int J Pediatr Otorhinolaryngol. 39(2):139-46, 1997
                                          19. Nguyen Q et al: Cervical thymic cyst: case reports and review of the literature. Laryngoscope. 106(3 Pt 1):247-52, 1996
                                          20. Benson MT et al: Congenital anomalies of the branchial apparatus: embryology and pathologic anatomy. Radiographics. 12(5):943-60, 1992
                                          21. Zarbo RJ et al: Thymopharyngeal duct cyst: a form of cervical thymus. Ann Otol Rhinol Laryngol. 92(3 Pt 1):284-9, 1983
                                          Related Anatomy
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                                          Related Differential Diagnoses
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                                          References
                                          Tables

                                          Tables

                                          KEY FACTS

                                          • Terminology

                                            • Imaging

                                              • Top Differential Diagnoses

                                                • Clinical Issues

                                                  • Diagnostic Checklist

                                                    TERMINOLOGY

                                                    • Abbreviations

                                                      • 3rd branchial cleft cyst (BCC)
                                                    • Synonyms

                                                      • 3rd branchial apparatus cyst (BAC)
                                                    • Definitions

                                                      • Epithelial-lined cystic remnant of 3rd branchial cleft

                                                    IMAGING

                                                    • General Features

                                                      • Fluoroscopic Findings

                                                        • CT Findings

                                                          • MR Findings

                                                            • Ultrasonographic Findings

                                                              • Imaging Recommendations

                                                                DIFFERENTIAL DIAGNOSIS

                                                                  PATHOLOGY

                                                                  • General Features

                                                                    • Gross Pathologic & Surgical Features

                                                                      • Microscopic Features

                                                                        CLINICAL ISSUES

                                                                        • Presentation

                                                                          • Demographics

                                                                            • Natural History & Prognosis

                                                                              • Treatment

                                                                                DIAGNOSTIC CHECKLIST

                                                                                • Consider

                                                                                  Selected References

                                                                                  1. Goff CJ et al: Current management of congenital branchial cleft cysts, sinuses, and fistulae. Curr Opin Otolaryngol Head Neck Surg. 20(6):533-9, 2012
                                                                                  2. Bajaj Y et al: Branchial anomalies in children. Int J Pediatr Otorhinolaryngol. 75(8):1020-3, 2011
                                                                                  3. Pahlavan S et al: Microbiology of third and fourth branchial pouch cysts. Laryngoscope. 120(3):458-62, 2010
                                                                                  4. Thomas B et al: Revisiting imaging features and the embryologic basis of third and fourth branchial anomalies. AJNR Am J Neuroradiol. 31(4):755-60, 2010
                                                                                  5. Joshi MJ et al: The rare third branchial cleft cyst. AJNR Am J Neuroradiol. 30(9):1804-6, 2009
                                                                                  6. Koch BL: Cystic malformations of the neck in children. Pediatr Radiol. 35(5):463-77, 2005
                                                                                  7. Khariwala SS et al: Cervical presentations of thymic anomalies in children. Int J Pediatr Otorhinolaryngol. 68(7):909-14, 2004
                                                                                  8. Pereira KD et al: Management of anomalies of the third and fourth branchial pouches. Int J Pediatr Otorhinolaryngol. 68(1):43-50, 2004
                                                                                  9. Tsai CC et al: Branchial-cleft sinus presenting with a retropharyngeal abscess for a newborn: a case report. Am J Perinatol. 20(5):227-31, 2003
                                                                                  10. Liberman M et al: Ten years of experience with third and fourth branchial remnants. J Pediatr Surg. 37(5):685-90, 2002
                                                                                  11. Huang RY et al: Third branchial cleft anomaly presenting as a retropharyngeal abscess. Int J Pediatr Otorhinolaryngol. 54(2-3):167-72, 2000
                                                                                  12. Mandell DL: Head and neck anomalies related to the branchial apparatus. Otolaryngol Clin North Am. 33(6):1309-32, 2000
                                                                                  13. Mukherji SK et al: Imaging of congenital anomalies of the branchial apparatus. Neuroimaging Clin N Am. 10(1):75-93, viii, 2000
                                                                                  14. Nicollas R et al: Congenital cysts and fistulas of the neck. Int J Pediatr Otorhinolaryngol. 55(2):117-24, 2000
                                                                                  15. Koeller KK et al: Congenital cystic masses of the neck: radiologic-pathologic correlation. Radiographics. 19(1):121-46; quiz 152-3, 1999
                                                                                  16. Mouri N et al: Reappraisal of lateral cervical cysts in neonates: pyriform sinus cysts as an anatomy-based nomenclature. J Pediatr Surg. 33(7):1141-4, 1998
                                                                                  17. Edmonds JL et al: Third branchial anomalies. Avoiding recurrences. Arch Otolaryngol Head Neck Surg. 123(4):438-41, 1997
                                                                                  18. Kelley DJ et al: Cervicomediastinal thymic cysts. Int J Pediatr Otorhinolaryngol. 39(2):139-46, 1997
                                                                                  19. Nguyen Q et al: Cervical thymic cyst: case reports and review of the literature. Laryngoscope. 106(3 Pt 1):247-52, 1996
                                                                                  20. Benson MT et al: Congenital anomalies of the branchial apparatus: embryology and pathologic anatomy. Radiographics. 12(5):943-60, 1992
                                                                                  21. Zarbo RJ et al: Thymopharyngeal duct cyst: a form of cervical thymus. Ann Otol Rhinol Laryngol. 92(3 Pt 1):284-9, 1983