Primary CMV infection: Generally asymptomatic in healthy adults
Immunocompromised (AIDS, organ transplant) patients at risk → reactivation of previously silent infection
IMAGING
General Features
Imaging Recommendations
CT Findings
MR Findings
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
Selected References
Angstwurm K et al: [Infections of the central nervous system in immunodeficiency.] Internist (Berl). 60(7):690-700, 2019
Shih RY et al: Central nervous system lesions in immunocompromised patients. Radiol Clin North Am. 57(6):1217-31, 2019
Sonneville R et al: Central nervous system infections in immunocompromised patients. Curr Opin Crit Care. 23(2):128-33, 2017
Bowen LN et al: HIV-associated opportunistic CNS infections: pathophysiology, diagnosis and treatment. Nat Rev Neurol. 12(11):662-74, 2016
Renard T et al: Cytomegalovirus encephalitis: undescribed diffusion-weighted imaging characteristics. Original aspects of cases extracted from a retrospective study, and from literature review. J Neuroradiol. 43(6):371-7, 2016
Bilgrami M et al: Neurologic diseases in HIV-infected patients. Handb Clin Neurol. 121:1321-44, 2014
Silva CA et al: Neurologic cytomegalovirus complications in patients with AIDS: retrospective review of 13 cases and review of the literature. Rev Inst Med Trop Sao Paulo. 52(6):305-10, 2010
Pirskanen-Matell R et al: Impairment of short-term memory and Korsakoff syndrome are common in AIDS patients with cytomegalovirus encephalitis. Eur J Neurol. 16(1):48-53, 2009
Rafailidis PI et al: Severe cytomegalovirus infection in apparently immunocompetent patients: a systematic review. Virol J. 5:47, 2008
Miller RF et al: Comparison of magnetic resonance imaging with neuropathological findings in the diagnosis of HIV and CMV associated CNS disease in AIDS. J Neurol Neurosurg Psychiatry. 62(4):346-51, 1997
Holland NR et al: Cytomegalovirus encephalitis in acquired immunodeficiency syndrome (AIDS). Neurology. 44(3 Pt 1):507-14, 1994
Balakrishnan J et al: Acquired immunodeficiency syndrome: correlation of radiologic and pathologic findings in the brain. Radiographics. 10(2):201-15, 1990
Primary CMV infection: Generally asymptomatic in healthy adults
Immunocompromised (AIDS, organ transplant) patients at risk → reactivation of previously silent infection
IMAGING
General Features
Imaging Recommendations
CT Findings
MR Findings
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
Selected References
Angstwurm K et al: [Infections of the central nervous system in immunodeficiency.] Internist (Berl). 60(7):690-700, 2019
Shih RY et al: Central nervous system lesions in immunocompromised patients. Radiol Clin North Am. 57(6):1217-31, 2019
Sonneville R et al: Central nervous system infections in immunocompromised patients. Curr Opin Crit Care. 23(2):128-33, 2017
Bowen LN et al: HIV-associated opportunistic CNS infections: pathophysiology, diagnosis and treatment. Nat Rev Neurol. 12(11):662-74, 2016
Renard T et al: Cytomegalovirus encephalitis: undescribed diffusion-weighted imaging characteristics. Original aspects of cases extracted from a retrospective study, and from literature review. J Neuroradiol. 43(6):371-7, 2016
Bilgrami M et al: Neurologic diseases in HIV-infected patients. Handb Clin Neurol. 121:1321-44, 2014
Silva CA et al: Neurologic cytomegalovirus complications in patients with AIDS: retrospective review of 13 cases and review of the literature. Rev Inst Med Trop Sao Paulo. 52(6):305-10, 2010
Pirskanen-Matell R et al: Impairment of short-term memory and Korsakoff syndrome are common in AIDS patients with cytomegalovirus encephalitis. Eur J Neurol. 16(1):48-53, 2009
Rafailidis PI et al: Severe cytomegalovirus infection in apparently immunocompetent patients: a systematic review. Virol J. 5:47, 2008
Miller RF et al: Comparison of magnetic resonance imaging with neuropathological findings in the diagnosis of HIV and CMV associated CNS disease in AIDS. J Neurol Neurosurg Psychiatry. 62(4):346-51, 1997
Holland NR et al: Cytomegalovirus encephalitis in acquired immunodeficiency syndrome (AIDS). Neurology. 44(3 Pt 1):507-14, 1994
Balakrishnan J et al: Acquired immunodeficiency syndrome: correlation of radiologic and pathologic findings in the brain. Radiographics. 10(2):201-15, 1990
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