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Acquired Cystic Kidney Disease
Ghaneh Fananapazir, MD, FSAR, FSRU, FSABI; Alessandro Furlan, MD
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Clinical Issues

          TERMINOLOGY

          • Synonyms

            • Uremic cystic disease
          • Definitions

            • Acquired cystic kidney disease (ACKD): Numerous cysts in patients with end-stage renal disease and no history of hereditary cystic disease

          IMAGING

          • General Features

            • CT Findings

              • MR Findings

                • Ultrasonographic Findings

                  • Imaging Recommendations

                    DIFFERENTIAL DIAGNOSIS

                      PATHOLOGY

                      • General Features

                        • Gross Pathologic & Surgical Features

                          CLINICAL ISSUES

                          • Presentation

                            • Demographics

                              • Natural History & Prognosis

                                • Treatment

                                  Selected References

                                  1. Edo H et al: Acquired cystic disease-associated renal cell carcinoma extending to the renal pelvis mimicking urothelial carcinoma on computed tomography (CT): two case reports. Am J Case Rep. 21:e926630, 2020
                                  2. Rahbari-Oskoui F et al: Diagnosis and management of acquired cystic kidney disease and renal tumors in ESRD patients. Semin Dial. 30(4):373-9, 2017
                                  3. Degrassi F et al: Imaging of haemodialysis: renal and extrarenal findings. Insights Imaging. 6(3):309-21, 2015
                                  4. Wood CG 3rd et al: CT and MR imaging for evaluation of cystic renal lesions and diseases. Radiographics. 35(1):125-41, 2015
                                  5. Katabathina VS et al: Cystic renal neoplasms and renal neoplasms associated with cystic renal diseases in adults: cross-sectional imaging findings. J Comput Assist Tomogr. 36(6):659-68, 2012
                                  6. Hurst FP et al: Incidence, predictors and associated outcomes of renal cell carcinoma in long-term dialysis patients. Urology. 77(6):1271-6, 2011
                                  7. Katabathina VS et al: Adult renal cystic disease: a genetic, biological, and developmental primer. Radiographics. 30(6):1509-23, 2010
                                  8. Tickoo SK et al: Spectrum of epithelial neoplasms in end-stage renal disease: an experience from 66 tumor-bearing kidneys with emphasis on histologic patterns distinct from those in sporadic adult renal neoplasia. Am J Surg Pathol. 30(2):141-53, 2006
                                  9. Truong LD et al: Renal cystic neoplasms and renal neoplasms associated with cystic renal diseases: pathogenetic and molecular links. Adv Anat Pathol. 10(3):135-59, 2003
                                  10. Denton MD et al: Prevalence of renal cell carcinoma in patients with ESRD pre-transplantation: a pathologic analysis. Kidney Int. 61(6):2201-9, 2002
                                  11. Choyke PL: Acquired cystic kidney disease. Eur Radiol. 10:1716-21, 2000
                                  Related Anatomy
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                                  Related Differential Diagnoses
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                                  References
                                  Tables

                                  Tables

                                  KEY FACTS

                                  • Terminology

                                    • Imaging

                                      • Top Differential Diagnoses

                                        • Clinical Issues

                                          TERMINOLOGY

                                          • Synonyms

                                            • Uremic cystic disease
                                          • Definitions

                                            • Acquired cystic kidney disease (ACKD): Numerous cysts in patients with end-stage renal disease and no history of hereditary cystic disease

                                          IMAGING

                                          • General Features

                                            • CT Findings

                                              • MR Findings

                                                • Ultrasonographic Findings

                                                  • Imaging Recommendations

                                                    DIFFERENTIAL DIAGNOSIS

                                                      PATHOLOGY

                                                      • General Features

                                                        • Gross Pathologic & Surgical Features

                                                          CLINICAL ISSUES

                                                          • Presentation

                                                            • Demographics

                                                              • Natural History & Prognosis

                                                                • Treatment

                                                                  Selected References

                                                                  1. Edo H et al: Acquired cystic disease-associated renal cell carcinoma extending to the renal pelvis mimicking urothelial carcinoma on computed tomography (CT): two case reports. Am J Case Rep. 21:e926630, 2020
                                                                  2. Rahbari-Oskoui F et al: Diagnosis and management of acquired cystic kidney disease and renal tumors in ESRD patients. Semin Dial. 30(4):373-9, 2017
                                                                  3. Degrassi F et al: Imaging of haemodialysis: renal and extrarenal findings. Insights Imaging. 6(3):309-21, 2015
                                                                  4. Wood CG 3rd et al: CT and MR imaging for evaluation of cystic renal lesions and diseases. Radiographics. 35(1):125-41, 2015
                                                                  5. Katabathina VS et al: Cystic renal neoplasms and renal neoplasms associated with cystic renal diseases in adults: cross-sectional imaging findings. J Comput Assist Tomogr. 36(6):659-68, 2012
                                                                  6. Hurst FP et al: Incidence, predictors and associated outcomes of renal cell carcinoma in long-term dialysis patients. Urology. 77(6):1271-6, 2011
                                                                  7. Katabathina VS et al: Adult renal cystic disease: a genetic, biological, and developmental primer. Radiographics. 30(6):1509-23, 2010
                                                                  8. Tickoo SK et al: Spectrum of epithelial neoplasms in end-stage renal disease: an experience from 66 tumor-bearing kidneys with emphasis on histologic patterns distinct from those in sporadic adult renal neoplasia. Am J Surg Pathol. 30(2):141-53, 2006
                                                                  9. Truong LD et al: Renal cystic neoplasms and renal neoplasms associated with cystic renal diseases: pathogenetic and molecular links. Adv Anat Pathol. 10(3):135-59, 2003
                                                                  10. Denton MD et al: Prevalence of renal cell carcinoma in patients with ESRD pre-transplantation: a pathologic analysis. Kidney Int. 61(6):2201-9, 2002
                                                                  11. Choyke PL: Acquired cystic kidney disease. Eur Radiol. 10:1716-21, 2000