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Actinomycosis
Carlos S. Restrepo, MD; Tomás Franquet, MD, PhD
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Pathology

          • Clinical Issues

            • Diagnostic Checklist

              TERMINOLOGY

              • Definitions

                • Granulomatous infection caused by Actinomyces species, most commonly A. israelii; gram-positive filamentous anaerobic saprophytic organism
                  • Parenchymal actinomycosis: Aspiration of endogenous oropharyngeal organisms into lungs
                  • Bronchiectatic actinomycosis: Colonization of devitalized tissue and bronchiectasis
                  • Endobronchial actinomycosis associated with broncholithiasis or foreign body: Colonization of preexisting endobronchial broncholith/foreign body

              IMAGING

              • Radiographic Findings

                • CT Findings

                  • Nuclear Medicine Findings

                    • Imaging Recommendations

                      DIFFERENTIAL DIAGNOSIS

                        PATHOLOGY

                        • General Features

                          • Gross Pathologic & Surgical Features

                            • Microscopic Features

                              CLINICAL ISSUES

                              • Presentation

                                • Demographics

                                  • Natural History & Prognosis

                                    • Treatment

                                      DIAGNOSTIC CHECKLIST

                                      • Consider

                                        • Image Interpretation Pearls

                                          • Reporting Tips

                                            Selected References

                                            1. Tanaka S et al: Pulmonary actinomycosis mimicking pulmonary cancer on fluorine-18 fluorodeoxyglucose PET-CT. Cureus. 12(12):e12306, 2020
                                            2. Higashi Y et al: Pulmonary actinomycosis mimicking pulmonary aspergilloma and a brief review of the literature. Intern Med. 56(4):449-53, 2017
                                            3. Valour F et al: Actinomycosis: etiology, clinical features, diagnosis, treatment, and management. Infect Drug Resist. 7:183-97, 2014
                                            4. Kim SR et al: Pulmonary actinomycosis during the first decade of 21st century: cases of 94 patients. BMC Infect Dis. 13:216, 2013
                                            Related Anatomy
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                                            Related Differential Diagnoses
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                                            References
                                            Tables

                                            Tables

                                            KEY FACTS

                                            • Terminology

                                              • Imaging

                                                • Top Differential Diagnoses

                                                  • Pathology

                                                    • Clinical Issues

                                                      • Diagnostic Checklist

                                                        TERMINOLOGY

                                                        • Definitions

                                                          • Granulomatous infection caused by Actinomyces species, most commonly A. israelii; gram-positive filamentous anaerobic saprophytic organism
                                                            • Parenchymal actinomycosis: Aspiration of endogenous oropharyngeal organisms into lungs
                                                            • Bronchiectatic actinomycosis: Colonization of devitalized tissue and bronchiectasis
                                                            • Endobronchial actinomycosis associated with broncholithiasis or foreign body: Colonization of preexisting endobronchial broncholith/foreign body

                                                        IMAGING

                                                        • Radiographic Findings

                                                          • CT Findings

                                                            • Nuclear Medicine Findings

                                                              • Imaging Recommendations

                                                                DIFFERENTIAL DIAGNOSIS

                                                                  PATHOLOGY

                                                                  • General Features

                                                                    • Gross Pathologic & Surgical Features

                                                                      • Microscopic Features

                                                                        CLINICAL ISSUES

                                                                        • Presentation

                                                                          • Demographics

                                                                            • Natural History & Prognosis

                                                                              • Treatment

                                                                                DIAGNOSTIC CHECKLIST

                                                                                • Consider

                                                                                  • Image Interpretation Pearls

                                                                                    • Reporting Tips

                                                                                      Selected References

                                                                                      1. Tanaka S et al: Pulmonary actinomycosis mimicking pulmonary cancer on fluorine-18 fluorodeoxyglucose PET-CT. Cureus. 12(12):e12306, 2020
                                                                                      2. Higashi Y et al: Pulmonary actinomycosis mimicking pulmonary aspergilloma and a brief review of the literature. Intern Med. 56(4):449-53, 2017
                                                                                      3. Valour F et al: Actinomycosis: etiology, clinical features, diagnosis, treatment, and management. Infect Drug Resist. 7:183-97, 2014
                                                                                      4. Kim SR et al: Pulmonary actinomycosis during the first decade of 21st century: cases of 94 patients. BMC Infect Dis. 13:216, 2013