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Acute Hypertensive Encephalopathy, PRES
Anne G. Osborn, MD, FACR
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Pathology

          • Clinical Issues

            TERMINOLOGY

            • Abbreviations

              • Posterior reversible encephalopathy syndrome (PRES)
            • Synonyms

              • Hypertensive encephalopathy
              • Reversible posterior leukoencephalopathy syndrome (RPLS)
            • Definitions

              • Variant of hypertensive encephalopathy characterized by headache, visual disturbances, altered mental function
              • Cerebrovascular autoregulatory disorder
                • Multiple etiologies
                • Most caused by acute hypertension (HTN)

            IMAGING

            • General Features

              • CT Findings

                • MR Findings

                  • Nuclear Medicine Findings

                    • Imaging Recommendations

                      DIFFERENTIAL DIAGNOSIS

                        PATHOLOGY

                        • General Features

                          • Gross Pathologic & Surgical Features

                            • Microscopic Features

                              CLINICAL ISSUES

                              • Presentation

                                • Demographics

                                  • Natural History & Prognosis

                                    • Treatment

                                      DIAGNOSTIC CHECKLIST

                                      • Consider

                                        • Image Interpretation Pearls

                                          Selected References

                                          1. Brewer J et al: Posterior reversible encephalopathy syndrome in 46 of 47 patients with eclampsia. Am J Obstet Gynecol. 208(6):468, 2013
                                          2. Khosravani H et al: Emergency noninvasive angiography for acute intracerebral hemorrhage. AJNR Am J Neuroradiol. 34(8):1481-7, 2013
                                          3. Li R et al: Is hypertension predictive of clinical recurrence in posterior reversible encephalopathy syndrome? J Clin Neurosci. 20(2):248-52, 2013
                                          4. Peter P et al: Posterior reversible encephalopathy syndrome and the pediatric population. J Pediatr Neurosci. 7(2):136-8, 2012
                                          5. McCoy B et al: Childhood posterior reversible encephalopathy syndrome. Eur J Paediatr Neurol. 15(2):91-4, 2011
                                          6. Bartynski WS et al: Posterior reversible encephalopathy syndrome in infection, sepsis, and shock. AJNR Am J Neuroradiol. 27(10):2179-90, 2006
                                          7. Ishikura K et al: Posterior reversible encephalopathy syndrome in children: its high prevalence and more extensive imaging findings. Am J Kidney Dis. 48(2):231-8, 2006
                                          8. Mirza A: Posterior reversible encephalopathy syndrome: a variant of hypertensive encephalopathy. J Clin Neurosci. 13(5):590-5, 2006
                                          9. Narbone MC et al: PRES: posterior or potentially reversible encephalopathy syndrome? Neurol Sci. 27(3):187-9, 2006
                                          10. Pande AR et al: Clinicoradiological factors influencing the reversibility of posterior reversible encephalopathy syndrome: a multicenter study. Radiat Med. 24(10):659-68, 2006
                                          11. Kaito E et al: The role of tumor lysis in reversible posterior leukoencephalopathy syndrome. Pediatr Radiol. 35(7):722-7, 2005
                                          12. Striano P et al: Clinical spectrum and critical care management of Posterior Reversible Encephalopathy Syndrome (PRES). Med Sci Monit. 11(11):CR549-53, 2005
                                          Related Anatomy
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                                          Related Differential Diagnoses
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                                          References
                                          Tables

                                          Tables

                                          KEY FACTS

                                          • Terminology

                                            • Imaging

                                              • Top Differential Diagnoses

                                                • Pathology

                                                  • Clinical Issues

                                                    TERMINOLOGY

                                                    • Abbreviations

                                                      • Posterior reversible encephalopathy syndrome (PRES)
                                                    • Synonyms

                                                      • Hypertensive encephalopathy
                                                      • Reversible posterior leukoencephalopathy syndrome (RPLS)
                                                    • Definitions

                                                      • Variant of hypertensive encephalopathy characterized by headache, visual disturbances, altered mental function
                                                      • Cerebrovascular autoregulatory disorder
                                                        • Multiple etiologies
                                                        • Most caused by acute hypertension (HTN)

                                                    IMAGING

                                                    • General Features

                                                      • CT Findings

                                                        • MR Findings

                                                          • Nuclear Medicine Findings

                                                            • Imaging Recommendations

                                                              DIFFERENTIAL DIAGNOSIS

                                                                PATHOLOGY

                                                                • General Features

                                                                  • Gross Pathologic & Surgical Features

                                                                    • Microscopic Features

                                                                      CLINICAL ISSUES

                                                                      • Presentation

                                                                        • Demographics

                                                                          • Natural History & Prognosis

                                                                            • Treatment

                                                                              DIAGNOSTIC CHECKLIST

                                                                              • Consider

                                                                                • Image Interpretation Pearls

                                                                                  Selected References

                                                                                  1. Brewer J et al: Posterior reversible encephalopathy syndrome in 46 of 47 patients with eclampsia. Am J Obstet Gynecol. 208(6):468, 2013
                                                                                  2. Khosravani H et al: Emergency noninvasive angiography for acute intracerebral hemorrhage. AJNR Am J Neuroradiol. 34(8):1481-7, 2013
                                                                                  3. Li R et al: Is hypertension predictive of clinical recurrence in posterior reversible encephalopathy syndrome? J Clin Neurosci. 20(2):248-52, 2013
                                                                                  4. Peter P et al: Posterior reversible encephalopathy syndrome and the pediatric population. J Pediatr Neurosci. 7(2):136-8, 2012
                                                                                  5. McCoy B et al: Childhood posterior reversible encephalopathy syndrome. Eur J Paediatr Neurol. 15(2):91-4, 2011
                                                                                  6. Bartynski WS et al: Posterior reversible encephalopathy syndrome in infection, sepsis, and shock. AJNR Am J Neuroradiol. 27(10):2179-90, 2006
                                                                                  7. Ishikura K et al: Posterior reversible encephalopathy syndrome in children: its high prevalence and more extensive imaging findings. Am J Kidney Dis. 48(2):231-8, 2006
                                                                                  8. Mirza A: Posterior reversible encephalopathy syndrome: a variant of hypertensive encephalopathy. J Clin Neurosci. 13(5):590-5, 2006
                                                                                  9. Narbone MC et al: PRES: posterior or potentially reversible encephalopathy syndrome? Neurol Sci. 27(3):187-9, 2006
                                                                                  10. Pande AR et al: Clinicoradiological factors influencing the reversibility of posterior reversible encephalopathy syndrome: a multicenter study. Radiat Med. 24(10):659-68, 2006
                                                                                  11. Kaito E et al: The role of tumor lysis in reversible posterior leukoencephalopathy syndrome. Pediatr Radiol. 35(7):722-7, 2005
                                                                                  12. Striano P et al: Clinical spectrum and critical care management of Posterior Reversible Encephalopathy Syndrome (PRES). Med Sci Monit. 11(11):CR549-53, 2005