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Acute Tubular Necrosis
Alessandro Furlan, MD
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Pathology

          • Clinical Issues

            TERMINOLOGY

            • Abbreviations

              • Acute tubular necrosis (ATN)
              • Acute kidney injury (AKI)
                • Preferred term over acute renal failure (ARF)
            • Definitions

              • Renal cause of AKI characterized by tubular epithelial cell damage from toxins or ischemia

            IMAGING

            • Imaging Recommendations

              • Ultrasonographic Findings

                • CT Findings

                  • MR Findings

                    DIFFERENTIAL DIAGNOSIS

                      PATHOLOGY

                      • General Features

                        • Microscopic Features

                          CLINICAL ISSUES

                          • Presentation

                            • Demographics

                              • Natural History & Prognosis

                                • Treatment

                                  Selected References

                                  1. Thomas ME et al: The definition of acute kidney injury and its use in practice. Kidney Int. 87(1):62-73, 2015
                                  2. Faubel S et al: Renal relevant radiology: use of ultrasonography in patients with AKI. Clin J Am Soc Nephrol. 9(2):382-94, 2014
                                  3. Giannarini G et al: Functional multiparametric magnetic resonance imaging of the kidneys using blood oxygen level dependent and diffusion-weighted sequences. J Urol. 192(2):434-9, 2014
                                  4. He X et al: Estimation of single-kidney glomerular filtration rate without exogenous contrast agent. Magn Reson Med. 71(1):257-66, 2014
                                  5. Remer EM et al: ACR Appropriateness Criteria(®) on renal failure. Am J Med. 127(11):1041-8.e1, 2014
                                  6. Zhang JL et al: New magnetic resonance imaging methods in nephrology. Kidney Int. 85(4):768-78, 2014
                                  7. McDonald JS et al: Frequency of acute kidney injury following intravenous contrast medium administration: a systematic review and meta-analysis. Radiology. 267(1):119-28, 2013
                                  8. Ozmen CA et al: Ultrasound as a diagnostic tool to differentiate acute from chronic renal failure. Clin Nephrol. 74(1):46-52, 2010
                                  9. Garcia-Tsao G et al: Acute kidney injury in cirrhosis. Hepatology. 48(6):2064-77, 2008
                                  10. Kellum JA et al: Acute kidney injury: epidemiology and assessment. Scand J Clin Lab Invest Suppl. 241:6-11, 2008
                                  11. Schiffl H: Renal recovery after severe acute renal injury. Eur J Med Res. 13(12):552-6, 2008
                                  12. Gill N et al: Renal failure secondary to acute tubular necrosis: epidemiology, diagnosis, and management. Chest. 128(4):2847-63, 2005
                                  13. Tublin ME et al: Review. The resistive index in renal Doppler sonography: where do we stand? AJR Am J Roentgenol. 180(4):885-92, 2003
                                  14. Yassa NA et al: Perirenal lucency ("kidney sweat"): a new sign of renal failure. AJR Am J Roentgenol. 173(4):1075-7, 1999
                                  15. Platt JF: Duplex Doppler evaluation of native kidney dysfunction: obstructive and nonobstructive disease. AJR Am J Roentgenol. 158(5):1035-42, 1992
                                  Related Anatomy
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                                  Related Differential Diagnoses
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                                  References
                                  Tables

                                  Tables

                                  KEY FACTS

                                  • Terminology

                                    • Imaging

                                      • Top Differential Diagnoses

                                        • Pathology

                                          • Clinical Issues

                                            TERMINOLOGY

                                            • Abbreviations

                                              • Acute tubular necrosis (ATN)
                                              • Acute kidney injury (AKI)
                                                • Preferred term over acute renal failure (ARF)
                                            • Definitions

                                              • Renal cause of AKI characterized by tubular epithelial cell damage from toxins or ischemia

                                            IMAGING

                                            • Imaging Recommendations

                                              • Ultrasonographic Findings

                                                • CT Findings

                                                  • MR Findings

                                                    DIFFERENTIAL DIAGNOSIS

                                                      PATHOLOGY

                                                      • General Features

                                                        • Microscopic Features

                                                          CLINICAL ISSUES

                                                          • Presentation

                                                            • Demographics

                                                              • Natural History & Prognosis

                                                                • Treatment

                                                                  Selected References

                                                                  1. Thomas ME et al: The definition of acute kidney injury and its use in practice. Kidney Int. 87(1):62-73, 2015
                                                                  2. Faubel S et al: Renal relevant radiology: use of ultrasonography in patients with AKI. Clin J Am Soc Nephrol. 9(2):382-94, 2014
                                                                  3. Giannarini G et al: Functional multiparametric magnetic resonance imaging of the kidneys using blood oxygen level dependent and diffusion-weighted sequences. J Urol. 192(2):434-9, 2014
                                                                  4. He X et al: Estimation of single-kidney glomerular filtration rate without exogenous contrast agent. Magn Reson Med. 71(1):257-66, 2014
                                                                  5. Remer EM et al: ACR Appropriateness Criteria(®) on renal failure. Am J Med. 127(11):1041-8.e1, 2014
                                                                  6. Zhang JL et al: New magnetic resonance imaging methods in nephrology. Kidney Int. 85(4):768-78, 2014
                                                                  7. McDonald JS et al: Frequency of acute kidney injury following intravenous contrast medium administration: a systematic review and meta-analysis. Radiology. 267(1):119-28, 2013
                                                                  8. Ozmen CA et al: Ultrasound as a diagnostic tool to differentiate acute from chronic renal failure. Clin Nephrol. 74(1):46-52, 2010
                                                                  9. Garcia-Tsao G et al: Acute kidney injury in cirrhosis. Hepatology. 48(6):2064-77, 2008
                                                                  10. Kellum JA et al: Acute kidney injury: epidemiology and assessment. Scand J Clin Lab Invest Suppl. 241:6-11, 2008
                                                                  11. Schiffl H: Renal recovery after severe acute renal injury. Eur J Med Res. 13(12):552-6, 2008
                                                                  12. Gill N et al: Renal failure secondary to acute tubular necrosis: epidemiology, diagnosis, and management. Chest. 128(4):2847-63, 2005
                                                                  13. Tublin ME et al: Review. The resistive index in renal Doppler sonography: where do we stand? AJR Am J Roentgenol. 180(4):885-92, 2003
                                                                  14. Yassa NA et al: Perirenal lucency ("kidney sweat"): a new sign of renal failure. AJR Am J Roentgenol. 173(4):1075-7, 1999
                                                                  15. Platt JF: Duplex Doppler evaluation of native kidney dysfunction: obstructive and nonobstructive disease. AJR Am J Roentgenol. 158(5):1035-42, 1992