Adamantinoma of long bones, extragnathic adamantinoma, differentiated adamantinoma, juvenile intracortical adamantinoma
Definitions
Low-grade, locally aggressive, malignant lesion usually arising in tibial cortex
IMAGING
General Features
Radiographic Findings
CT Findings
MR Findings
Imaging Recommendations
Image-Guided Biopsy
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Staging, Grading, & Classification
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Reporting Tips
Selected References
Nielsen GP et al: Adamantinoma of long bones. In Fletcher CDM et al: WHO Classification of Tumours: Tumours of Soft Tissue and Bone. IARC Press. 463-6, 2020
Rekhi B et al: Clinicopathologic features of two rare cases of dedifferentiated adamantinomas, including diagnostic implications. Int J Surg Pathol. 27(2):193-202, 2019
Bethapudi S et al: Imaging in osteofibrous dysplasia, osteofibrous dysplasia-like adamantinoma, and classic adamantinoma. Clin Radiol. 69(2):200-8, 2014
Giannoulis DK et al: Multiple recurrences and late metastasis of adamantinoma in the tibia: a case report. J Orthop Surg (Hong Kong). 22(3):420-2, 2014
Ramanoudjame M et al: Is there a link between osteofibrous dysplasia and adamantinoma? Orthop Traumatol Surg Res. 97(8):877-80, 2011
Most MJ et al: Osteofibrous dysplasia and adamantinoma. J Am Acad Orthop Surg. 18(6):358-66, 2010
Szendroi M et al: Adamantinoma of long bones: a long-term follow-up study of 11 cases. Pathol Oncol Res. 15(2):209-16, 2009
Camp MD et al: Best cases from the AFIP: adamantinoma of the tibia and fibula with cytogenetic analysis. Radiographics. 28(4):1215-20, 2008
Gleason BC et al: Osteofibrous dysplasia and adamantinoma in children and adolescents: a clinicopathologic reappraisal. Am J Surg Pathol. 32(3):363-76, 2008
Khanna M et al: Osteofibrous dysplasia, osteofibrous dysplasia-like adamantinoma and adamantinoma: correlation of radiological imaging features with surgical histology and assessment of the use of radiology in contributing to needle biopsy diagnosis. Skeletal Radiol. 37(12):1077-84, 2008
Papagelopoulos PJ et al: Clinicopathological features, diagnosis, and treatment of adamantinoma of the long bones. Orthopedics. 30(3):211-5; quiz 216-7, 2007
Lee RS et al: Osteofibrous dysplasia of the tibia. Is there a need for a radical surgical approach? J Bone Joint Surg Br. 88(5):658-64, 2006
Van Rijn R et al: Adamantinoma in childhood: report of six cases and review of the literature. Pediatr Radiol. 36(10):1068-74, 2006
Van der Woude HJ et al: MRI of adamantinoma of long bones in correlation with histopathology. AJR Am J Roentgenol. 183(6):1737-44, 2004
Springfield DS et al: Relationship between osteofibrous dysplasia and adamantinoma. Clin Orthop Relat Res. (309):234-44, 1994
Related Anatomy
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Related Differential Diagnoses
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References
Tables
Tables
KEY FACTS
Terminology
Imaging
Clinical Issues
TERMINOLOGY
Synonyms
Adamantinoma of long bones, extragnathic adamantinoma, differentiated adamantinoma, juvenile intracortical adamantinoma
Definitions
Low-grade, locally aggressive, malignant lesion usually arising in tibial cortex
IMAGING
General Features
Radiographic Findings
CT Findings
MR Findings
Imaging Recommendations
Image-Guided Biopsy
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Staging, Grading, & Classification
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Reporting Tips
Selected References
Nielsen GP et al: Adamantinoma of long bones. In Fletcher CDM et al: WHO Classification of Tumours: Tumours of Soft Tissue and Bone. IARC Press. 463-6, 2020
Rekhi B et al: Clinicopathologic features of two rare cases of dedifferentiated adamantinomas, including diagnostic implications. Int J Surg Pathol. 27(2):193-202, 2019
Bethapudi S et al: Imaging in osteofibrous dysplasia, osteofibrous dysplasia-like adamantinoma, and classic adamantinoma. Clin Radiol. 69(2):200-8, 2014
Giannoulis DK et al: Multiple recurrences and late metastasis of adamantinoma in the tibia: a case report. J Orthop Surg (Hong Kong). 22(3):420-2, 2014
Ramanoudjame M et al: Is there a link between osteofibrous dysplasia and adamantinoma? Orthop Traumatol Surg Res. 97(8):877-80, 2011
Most MJ et al: Osteofibrous dysplasia and adamantinoma. J Am Acad Orthop Surg. 18(6):358-66, 2010
Szendroi M et al: Adamantinoma of long bones: a long-term follow-up study of 11 cases. Pathol Oncol Res. 15(2):209-16, 2009
Camp MD et al: Best cases from the AFIP: adamantinoma of the tibia and fibula with cytogenetic analysis. Radiographics. 28(4):1215-20, 2008
Gleason BC et al: Osteofibrous dysplasia and adamantinoma in children and adolescents: a clinicopathologic reappraisal. Am J Surg Pathol. 32(3):363-76, 2008
Khanna M et al: Osteofibrous dysplasia, osteofibrous dysplasia-like adamantinoma and adamantinoma: correlation of radiological imaging features with surgical histology and assessment of the use of radiology in contributing to needle biopsy diagnosis. Skeletal Radiol. 37(12):1077-84, 2008
Papagelopoulos PJ et al: Clinicopathological features, diagnosis, and treatment of adamantinoma of the long bones. Orthopedics. 30(3):211-5; quiz 216-7, 2007
Lee RS et al: Osteofibrous dysplasia of the tibia. Is there a need for a radical surgical approach? J Bone Joint Surg Br. 88(5):658-64, 2006
Van Rijn R et al: Adamantinoma in childhood: report of six cases and review of the literature. Pediatr Radiol. 36(10):1068-74, 2006
Van der Woude HJ et al: MRI of adamantinoma of long bones in correlation with histopathology. AJR Am J Roentgenol. 183(6):1737-44, 2004