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Adenoid Cystic Carcinoma, Airways
Juliana Bueno, MD
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Pathology

          • Clinical Issues

            • Diagnostic Checklist

              TERMINOLOGY

              • Abbreviations

                • Adenoid cystic carcinoma (ACC)
              • Synonyms

                • Cylindroma
                  • Old term for ACC
                  • No longer in use
              • Definitions

                • Rare primary malignant tracheal neoplasm arising from submucosal (tracheobronchial) glands
                • 2nd most common malignant tracheal neoplasm
                • 90% of primary tracheal neoplasms
                  • Squamous cell carcinoma (SCC)
                  • Adenoid cystic carcinoma
                  • Mucoepidermoid carcinoma

              IMAGING

              • General Features

                • Radiographic Findings

                  • CT Findings

                    • Imaging Recommendations

                      DIFFERENTIAL DIAGNOSIS

                        PATHOLOGY

                        • General Features

                          CLINICAL ISSUES

                          • Presentation

                            • Natural History & Prognosis

                              • Treatment

                                DIAGNOSTIC CHECKLIST

                                • Consider

                                  • Image Interpretation Pearls

                                    Selected References

                                    1. Godoy MC et al: Multidetector CT evaluation of airway stents: what the radiologist should know. Radiographics. 34(7):1793-806, 2014
                                    2. Junker K: Pathology of tracheal tumors. Thorac Surg Clin. 24(1):7-11, 2014
                                    3. Wu CC et al: Tracheal and airway neoplasms. Semin Roentgenol. 48(4):354-64, 2013
                                    4. Calzada AP et al: Adenoid cystic carcinoma of the airway: a 30-year review at one institution. Am J Otolaryngol. Epub ahead of print, 2011
                                    5. Dean CW et al: AIRP best cases in radiologic-pathologic correlation: adenoid cystic carcinoma of the trachea. Radiographics. 31(5):1443-7, 2011
                                    6. Shadmehr MB et al: Primary major airway tumors; management and results. Eur J Cardiothorac Surg. 39(5):749-54, 2011
                                    7. Honings J et al: Clinical aspects and treatment of primary tracheal malignancies. Acta Otolaryngol. 130(7):763-72, 2010
                                    8. Honings J et al: Prognostic value of pathologic characteristics and resection margins in tracheal adenoid cystic carcinoma. Eur J Cardiothorac Surg. 37(6):1438-44, 2010
                                    9. Park CM et al: Tumors in the tracheobronchial tree: CT and FDG PET features. Radiographics. 29(1):55-71, 2009
                                    10. Macchiarini P: Primary tracheal tumours. Lancet Oncol. 7(1):83-91, 2006
                                    11. Mathisen DJ: Tracheal tumors. Chest Surg Clin N Am. 6(4):875-98, 1996
                                    12. McCarthy MJ et al: Tumors of the trachea. J Thorac Imaging. 10(3):180-98, 1995
                                    13. Worrell JA: Radiology of the central airways. Otolaryngol Clin North Am. 28(4):701-20, 1995
                                    14. Allen MS: Malignant tracheal tumors. Mayo Clin Proc. 68(7):680-4, 1993
                                    Related Anatomy
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                                    Related Differential Diagnoses
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                                    References
                                    Tables

                                    Tables

                                    KEY FACTS

                                    • Terminology

                                      • Imaging

                                        • Top Differential Diagnoses

                                          • Pathology

                                            • Clinical Issues

                                              • Diagnostic Checklist

                                                TERMINOLOGY

                                                • Abbreviations

                                                  • Adenoid cystic carcinoma (ACC)
                                                • Synonyms

                                                  • Cylindroma
                                                    • Old term for ACC
                                                    • No longer in use
                                                • Definitions

                                                  • Rare primary malignant tracheal neoplasm arising from submucosal (tracheobronchial) glands
                                                  • 2nd most common malignant tracheal neoplasm
                                                  • 90% of primary tracheal neoplasms
                                                    • Squamous cell carcinoma (SCC)
                                                    • Adenoid cystic carcinoma
                                                    • Mucoepidermoid carcinoma

                                                IMAGING

                                                • General Features

                                                  • Radiographic Findings

                                                    • CT Findings

                                                      • Imaging Recommendations

                                                        DIFFERENTIAL DIAGNOSIS

                                                          PATHOLOGY

                                                          • General Features

                                                            CLINICAL ISSUES

                                                            • Presentation

                                                              • Natural History & Prognosis

                                                                • Treatment

                                                                  DIAGNOSTIC CHECKLIST

                                                                  • Consider

                                                                    • Image Interpretation Pearls

                                                                      Selected References

                                                                      1. Godoy MC et al: Multidetector CT evaluation of airway stents: what the radiologist should know. Radiographics. 34(7):1793-806, 2014
                                                                      2. Junker K: Pathology of tracheal tumors. Thorac Surg Clin. 24(1):7-11, 2014
                                                                      3. Wu CC et al: Tracheal and airway neoplasms. Semin Roentgenol. 48(4):354-64, 2013
                                                                      4. Calzada AP et al: Adenoid cystic carcinoma of the airway: a 30-year review at one institution. Am J Otolaryngol. Epub ahead of print, 2011
                                                                      5. Dean CW et al: AIRP best cases in radiologic-pathologic correlation: adenoid cystic carcinoma of the trachea. Radiographics. 31(5):1443-7, 2011
                                                                      6. Shadmehr MB et al: Primary major airway tumors; management and results. Eur J Cardiothorac Surg. 39(5):749-54, 2011
                                                                      7. Honings J et al: Clinical aspects and treatment of primary tracheal malignancies. Acta Otolaryngol. 130(7):763-72, 2010
                                                                      8. Honings J et al: Prognostic value of pathologic characteristics and resection margins in tracheal adenoid cystic carcinoma. Eur J Cardiothorac Surg. 37(6):1438-44, 2010
                                                                      9. Park CM et al: Tumors in the tracheobronchial tree: CT and FDG PET features. Radiographics. 29(1):55-71, 2009
                                                                      10. Macchiarini P: Primary tracheal tumours. Lancet Oncol. 7(1):83-91, 2006
                                                                      11. Mathisen DJ: Tracheal tumors. Chest Surg Clin N Am. 6(4):875-98, 1996
                                                                      12. McCarthy MJ et al: Tumors of the trachea. J Thorac Imaging. 10(3):180-98, 1995
                                                                      13. Worrell JA: Radiology of the central airways. Otolaryngol Clin North Am. 28(4):701-20, 1995
                                                                      14. Allen MS: Malignant tracheal tumors. Mayo Clin Proc. 68(7):680-4, 1993