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Adrenal Carcinoma
Sonya Y. Khan, MD; Fauzia Vandermeer, MD
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Clinical Issues

          • Diagnostic Checklist

            TERMINOLOGY

            • Synonyms

              • Adrenocortical carcinoma (ACC); adrenal cancer
            • Definitions

              • Malignant neoplasm arising from adrenal cortex

            IMAGING

            • General Features

              • Ultrasonographic Findings

                • CT Findings

                  • MR Findings

                    • Angiographic Findings

                      • Nuclear Medicine Findings

                        • Imaging Recommendations

                          DIFFERENTIAL DIAGNOSIS

                            PATHOLOGY

                            • General Features

                              • Staging, Grading, & Classification

                                • Gross Pathologic & Surgical Features

                                  • Microscopic Features

                                    CLINICAL ISSUES

                                    • Presentation

                                      • Demographics

                                        • Natural History & Prognosis

                                          • Treatment

                                            DIAGNOSTIC CHECKLIST

                                            • Consider

                                              • Image Interpretation Pearls

                                                • Reporting Tips

                                                  Selected References

                                                  1. Ganeshan D et al: Current update on cytogenetics, taxonomy, diagnosis, and management of adrenocortical carcinoma: what radiologists should know. AJR Am J Roentgenol. 199(6):1283-93, 2012
                                                  2. Bharwani N et al: Adrenocortical carcinoma: the range of appearances on CT and MRI. AJR Am J Roentgenol. 196(6):W706-14, 2011
                                                  3. Johnson PT et al: Adrenal mass imaging with multidetector CT: pathologic conditions, pearls, and pitfalls. Radiographics. 29(5):1333-51, 2009
                                                  4. Leboulleux S et al: Diagnostic and prognostic value of 18-fluorodeoxyglucose positron emission tomography in adrenocortical carcinoma: a prospective comparison with computed tomography. J Clin Endocrinol Metab. 91(3):920-5, 2006
                                                  5. Caoili EM et al: Adrenal masses: characterization with combined unenhanced and delayed enhanced CT. Radiology. 222(3):629-33, 2002
                                                  Related Anatomy
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                                                  Related Differential Diagnoses
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                                                  References
                                                  Tables

                                                  Tables

                                                  KEY FACTS

                                                  • Terminology

                                                    • Imaging

                                                      • Top Differential Diagnoses

                                                        • Clinical Issues

                                                          • Diagnostic Checklist

                                                            TERMINOLOGY

                                                            • Synonyms

                                                              • Adrenocortical carcinoma (ACC); adrenal cancer
                                                            • Definitions

                                                              • Malignant neoplasm arising from adrenal cortex

                                                            IMAGING

                                                            • General Features

                                                              • Ultrasonographic Findings

                                                                • CT Findings

                                                                  • MR Findings

                                                                    • Angiographic Findings

                                                                      • Nuclear Medicine Findings

                                                                        • Imaging Recommendations

                                                                          DIFFERENTIAL DIAGNOSIS

                                                                            PATHOLOGY

                                                                            • General Features

                                                                              • Staging, Grading, & Classification

                                                                                • Gross Pathologic & Surgical Features

                                                                                  • Microscopic Features

                                                                                    CLINICAL ISSUES

                                                                                    • Presentation

                                                                                      • Demographics

                                                                                        • Natural History & Prognosis

                                                                                          • Treatment

                                                                                            DIAGNOSTIC CHECKLIST

                                                                                            • Consider

                                                                                              • Image Interpretation Pearls

                                                                                                • Reporting Tips

                                                                                                  Selected References

                                                                                                  1. Ganeshan D et al: Current update on cytogenetics, taxonomy, diagnosis, and management of adrenocortical carcinoma: what radiologists should know. AJR Am J Roentgenol. 199(6):1283-93, 2012
                                                                                                  2. Bharwani N et al: Adrenocortical carcinoma: the range of appearances on CT and MRI. AJR Am J Roentgenol. 196(6):W706-14, 2011
                                                                                                  3. Johnson PT et al: Adrenal mass imaging with multidetector CT: pathologic conditions, pearls, and pitfalls. Radiographics. 29(5):1333-51, 2009
                                                                                                  4. Leboulleux S et al: Diagnostic and prognostic value of 18-fluorodeoxyglucose positron emission tomography in adrenocortical carcinoma: a prospective comparison with computed tomography. J Clin Endocrinol Metab. 91(3):920-5, 2006
                                                                                                  5. Caoili EM et al: Adrenal masses: characterization with combined unenhanced and delayed enhanced CT. Radiology. 222(3):629-33, 2002