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Adrenal Collision Tumor
Mitchell Tublin, MD; Michael P. Federle, MD, FACR
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Diagnostic Checklist

          TERMINOLOGY

          • Abbreviations

            • Adrenal collision tumor (ACT)
          • Definitions

            • Coexistence of 2 contiguous but histologically different tumors within same adrenal gland
            • Not composition tumor (i.e., tumor with intermixed, differing cell types)

          IMAGING

          • General Features

            • CT Findings

              • MR Findings

                • Nuclear Medicine Findings

                  • Imaging Recommendations

                    DIFFERENTIAL DIAGNOSIS

                      PATHOLOGY

                      • General Features

                        • Gross Pathologic & Surgical Features

                          • Microscopic Features

                            CLINICAL ISSUES

                            • Presentation

                              • Demographics

                                • Natural History & Prognosis

                                  DIAGNOSTIC CHECKLIST

                                  • Consider

                                    Selected References

                                    1. Cicero G et al: Collision and composition tumors: rare conditions to remember in differential diagnosis of adrenal glands lesions. Quant Imaging Med Surg. 9(11):1902-3, 2019
                                    2. Foresti M et al: Adrenal adenoma-hemangioma collision tumor: description of two cases. J Radiol Case Rep. 13(6):1-12, 2019
                                    3. Pakalniskis MG et al: Adrenal collision tumour comprised of adrenocortical carcinoma and myelolipoma in a patient with congenital adrenal hyperplasia. J Med Imaging Radiat Oncol. 64(1):67-8, 2019
                                    4. Khorsand A et al: Adrenal collision tumor composed of pheochromocytoma and diffuse large B-cell lymphoma: a case report. Int J Hematol Oncol Stem Cell Res. 12(4):249-52, 2018
                                    5. Lee HS et al: Adrenal collision tumor: coexistence of pigmented adrenal cortical oncocytoma and ganglioneuroma. Case Rep Surg. 2016:5790645, 2016
                                    6. Piotrowski Z et al: Renal cell carcinoma and an incidental adrenal lesion: adrenal collision tumors. Urology. 85(3):e17-8, 2015
                                    7. Untch BR et al: Imaging and management of a small cell lung cancer metastasis/adrenal adenoma collision tumor: a case report and review of the literature. World J Surg Oncol. 12:45, 2014
                                    8. Katabathina VS et al: Adrenal collision tumors and their mimics: multimodality imaging findings. Cancer Imaging. 13(4):602-10, 2013
                                    9. Anderson SB et al: Adrenal collision tumor diagnosed by F-18 fluorodeoxyglucose PET/CT. Clin Nucl Med. 35(6):414-7, 2010
                                    10. Blake MA et al: Collision adrenal tumors on PET/CT. AJR Am J Roentgenol. 183(3):864-5, 2004
                                    Related Anatomy
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                                    Related Differential Diagnoses
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                                    References
                                    Tables

                                    Tables

                                    KEY FACTS

                                    • Terminology

                                      • Imaging

                                        • Top Differential Diagnoses

                                          • Diagnostic Checklist

                                            TERMINOLOGY

                                            • Abbreviations

                                              • Adrenal collision tumor (ACT)
                                            • Definitions

                                              • Coexistence of 2 contiguous but histologically different tumors within same adrenal gland
                                              • Not composition tumor (i.e., tumor with intermixed, differing cell types)

                                            IMAGING

                                            • General Features

                                              • CT Findings

                                                • MR Findings

                                                  • Nuclear Medicine Findings

                                                    • Imaging Recommendations

                                                      DIFFERENTIAL DIAGNOSIS

                                                        PATHOLOGY

                                                        • General Features

                                                          • Gross Pathologic & Surgical Features

                                                            • Microscopic Features

                                                              CLINICAL ISSUES

                                                              • Presentation

                                                                • Demographics

                                                                  • Natural History & Prognosis

                                                                    DIAGNOSTIC CHECKLIST

                                                                    • Consider

                                                                      Selected References

                                                                      1. Cicero G et al: Collision and composition tumors: rare conditions to remember in differential diagnosis of adrenal glands lesions. Quant Imaging Med Surg. 9(11):1902-3, 2019
                                                                      2. Foresti M et al: Adrenal adenoma-hemangioma collision tumor: description of two cases. J Radiol Case Rep. 13(6):1-12, 2019
                                                                      3. Pakalniskis MG et al: Adrenal collision tumour comprised of adrenocortical carcinoma and myelolipoma in a patient with congenital adrenal hyperplasia. J Med Imaging Radiat Oncol. 64(1):67-8, 2019
                                                                      4. Khorsand A et al: Adrenal collision tumor composed of pheochromocytoma and diffuse large B-cell lymphoma: a case report. Int J Hematol Oncol Stem Cell Res. 12(4):249-52, 2018
                                                                      5. Lee HS et al: Adrenal collision tumor: coexistence of pigmented adrenal cortical oncocytoma and ganglioneuroma. Case Rep Surg. 2016:5790645, 2016
                                                                      6. Piotrowski Z et al: Renal cell carcinoma and an incidental adrenal lesion: adrenal collision tumors. Urology. 85(3):e17-8, 2015
                                                                      7. Untch BR et al: Imaging and management of a small cell lung cancer metastasis/adrenal adenoma collision tumor: a case report and review of the literature. World J Surg Oncol. 12:45, 2014
                                                                      8. Katabathina VS et al: Adrenal collision tumors and their mimics: multimodality imaging findings. Cancer Imaging. 13(4):602-10, 2013
                                                                      9. Anderson SB et al: Adrenal collision tumor diagnosed by F-18 fluorodeoxyglucose PET/CT. Clin Nucl Med. 35(6):414-7, 2010
                                                                      10. Blake MA et al: Collision adrenal tumors on PET/CT. AJR Am J Roentgenol. 183(3):864-5, 2004