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Adrenal Hyperplasia
Ghaneh Fananapazir, MD, FSAR, FSRU, FSABI
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KEY FACTS

  • Imaging

    • Top Differential Diagnoses

      • Clinical Issues

        • Diagnostic Checklist

          TERMINOLOGY

          • Definitions

            • Bilateral adrenal gland hyperfunction ± enlargement

          IMAGING

          • General Features

            • CT Findings

              • MR Findings

                • Ultrasonographic Findings

                  • Nuclear Medicine Findings

                    • Imaging Recommendations

                      DIFFERENTIAL DIAGNOSIS

                        PATHOLOGY

                        • Gross Pathologic & Surgical Features

                          CLINICAL ISSUES

                          • Presentation

                            • Demographics

                              • Natural History & Prognosis

                                • Treatment

                                  DIAGNOSTIC CHECKLIST

                                  • Consider

                                    • Image Interpretation Pearls

                                      • Reporting Tips

                                        Selected References

                                        1. Morani AC et al: Adrenocortical hyperplasia: a review of clinical presentation and imaging. Abdom Radiol (NY). 45(4):917-27, 2020
                                        2. Michelle M A et al: Adrenal cortical hyperplasia: diagnostic workup, subtypes, imaging features and mimics. Br J Radiol. 90(1079):20170330, 2017
                                        3. Wagner-Bartak NA et al: Cushing syndrome: diagnostic workup and imaging features, with clinical and pathologic correlation. AJR Am J Roentgenol. 209(1):19-32, 2017
                                        4. Auchus RJ et al: Approach to the patient: the adult with congenital adrenal hyperplasia. J Clin Endocrinol Metab. 98(7):2645-55, 2013
                                        5. Sookur PA et al: Imaging in covert ectopic ACTH secretion: a CT pictorial review. Eur Radiol. 19(5):1069-78, 2009
                                        6. Sahdev A et al: Imaging in Cushing's syndrome. Arq Bras Endocrinol Metabol. 51(8):1319-28, 2007
                                        7. Rockall AG et al: CT and MR imaging of the adrenal glands in ACTH-independent cushing syndrome. Radiographics. 24(2):435-52, 2004
                                        8. Doppman JL et al: Adrenocorticotropin-independent macronodular adrenal hyperplasia: an uncommon cause of primary adrenal hypercortisolism. Radiology. 216(3):797-802, 2000
                                        Related Anatomy
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                                        Related Differential Diagnoses
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                                        References
                                        Tables

                                        Tables

                                        KEY FACTS

                                        • Imaging

                                          • Top Differential Diagnoses

                                            • Clinical Issues

                                              • Diagnostic Checklist

                                                TERMINOLOGY

                                                • Definitions

                                                  • Bilateral adrenal gland hyperfunction ± enlargement

                                                IMAGING

                                                • General Features

                                                  • CT Findings

                                                    • MR Findings

                                                      • Ultrasonographic Findings

                                                        • Nuclear Medicine Findings

                                                          • Imaging Recommendations

                                                            DIFFERENTIAL DIAGNOSIS

                                                              PATHOLOGY

                                                              • Gross Pathologic & Surgical Features

                                                                CLINICAL ISSUES

                                                                • Presentation

                                                                  • Demographics

                                                                    • Natural History & Prognosis

                                                                      • Treatment

                                                                        DIAGNOSTIC CHECKLIST

                                                                        • Consider

                                                                          • Image Interpretation Pearls

                                                                            • Reporting Tips

                                                                              Selected References

                                                                              1. Morani AC et al: Adrenocortical hyperplasia: a review of clinical presentation and imaging. Abdom Radiol (NY). 45(4):917-27, 2020
                                                                              2. Michelle M A et al: Adrenal cortical hyperplasia: diagnostic workup, subtypes, imaging features and mimics. Br J Radiol. 90(1079):20170330, 2017
                                                                              3. Wagner-Bartak NA et al: Cushing syndrome: diagnostic workup and imaging features, with clinical and pathologic correlation. AJR Am J Roentgenol. 209(1):19-32, 2017
                                                                              4. Auchus RJ et al: Approach to the patient: the adult with congenital adrenal hyperplasia. J Clin Endocrinol Metab. 98(7):2645-55, 2013
                                                                              5. Sookur PA et al: Imaging in covert ectopic ACTH secretion: a CT pictorial review. Eur Radiol. 19(5):1069-78, 2009
                                                                              6. Sahdev A et al: Imaging in Cushing's syndrome. Arq Bras Endocrinol Metabol. 51(8):1319-28, 2007
                                                                              7. Rockall AG et al: CT and MR imaging of the adrenal glands in ACTH-independent cushing syndrome. Radiographics. 24(2):435-52, 2004
                                                                              8. Doppman JL et al: Adrenocorticotropin-independent macronodular adrenal hyperplasia: an uncommon cause of primary adrenal hypercortisolism. Radiology. 216(3):797-802, 2000