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Adrenal Myelolipoma
Mitchell Tublin, MD; Michael P. Federle, MD, FACR
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17
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5

KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        TERMINOLOGY

        • Definitions

          • Uncommon benign tumor composed of mature adipose tissue and hematopoietic elements

        IMAGING

        • General Features

          • CT Findings

            • MR Findings

              • Ultrasonographic Findings

                • Angiographic Findings

                  • Nuclear Medicine Findings

                    • Imaging Recommendations

                      DIFFERENTIAL DIAGNOSIS

                        PATHOLOGY

                        • General Features

                          • Gross Pathologic & Surgical Features

                            • Microscopic Features

                              CLINICAL ISSUES

                              • Presentation

                                • Demographics

                                  • Natural History & Prognosis

                                    • Treatment

                                      DIAGNOSTIC CHECKLIST

                                      • Consider

                                        • Image Interpretation Pearls

                                          Selected References

                                          1. Alshahrani MA et al: Bilateral adrenal abnormalities: imaging review of different entities. Abdom Radiol (NY). 44(1):154-79, 2019
                                          2. Schieda N et al: Renal and adrenal masses containing fat at MRI: proposed nomenclature by the society of abdominal radiology disease-focused panel on renal cell carcinoma. J Magn Reson Imaging. 49(4):917-26, 2019
                                          3. Decmann Á et al: Adrenal myelolipoma: a comprehensive review. Endocrine. 59(1):7-15, 2018
                                          4. Campbell MJ et al: The radiographically diagnosed adrenal myelolipoma: what do we really know? Endocrine. 58(2):289-94, 2017
                                          5. Farrugia FA et al: Radiology of the adrenal incidentalomas. Review of the literature. Endocr Regul. 51(1):35-51, 2017
                                          6. Littrell LA et al: Extra-adrenal myelolipoma and extramedullary hematopoiesis: imaging features of two similar benign fat-containing presacral masses that may mimic liposarcoma. Eur J Radiol. 93:185-94, 2017
                                          7. Mendiratta-Lala M et al: Adrenal imaging. Endocrinol Metab Clin North Am. 46(3):741-59, 2017
                                          8. Tanner J et al: Case 243: extramedullary hematopoiesis in an adrenal myelolipoma. Radiology. 284(1):292-6, 2017
                                          9. Shaaban AM et al: Fat-containing retroperitoneal lesions: imaging characteristics, localization, and differential diagnosis. Radiographics. 36(3):710-34, 2016
                                          10. Yin L et al: A 10-year single-center experience with surgical management of adrenal myelolipoma. J Endourol. 28(2):252-5, 2014
                                          11. Schieda N et al: Pitfalls of adrenal imaging with chemical shift MRI. Clin Radiol. 69(11):1186-97, 2014
                                          12. Katabathina VS et al: Adrenal collision tumors and their mimics: multimodality imaging findings. Cancer Imaging. 13(4):602-10, 2013
                                          13. Castinetti F et al: Adrenal myelolipoma: an unusual cause of bilateral highly 18F-FDG-avid adrenal masses. J Clin Endocrinol Metab. 97(8):2577-8, 2012
                                          14. Giacinto J et al: Nonoperative management of adrenal myelolipoma hemorrhage resulting from trauma. Am Surg. 78(11):E463-4, 2012
                                          15. Su HC et al: Adrenal myelolipoma associated with hyperandrogenemia. Int J Urol. 19(11):1026-8, 2012
                                          16. German-Mena E et al: Adrenal myelolipomas in patients with congenital adrenal hyperplasia: review of the literature and a case report. Endocr Pract. 7(3):441-7, 2011
                                          17. Daneshmand S et al: Adrenal myelolipoma: diagnosis and management. Urol J. 3(2):71-4, 2006
                                          18. Kenney PJ et al: Myelolipoma: CT and pathologic features. Radiology. 208(1):87-95, 1998
                                          19. Rao P et al: Imaging and pathologic features of myelolipoma. Radiographics. 17(6):1373-85, 1997
                                          20. Cyran KM et al: Adrenal myelolipoma. AJR Am J Roentgenol. 166(2):395-400, 1996
                                          Related Anatomy
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                                          Related Differential Diagnoses
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                                          References
                                          Tables

                                          Tables

                                          KEY FACTS

                                          • Terminology

                                            • Imaging

                                              • Top Differential Diagnoses

                                                TERMINOLOGY

                                                • Definitions

                                                  • Uncommon benign tumor composed of mature adipose tissue and hematopoietic elements

                                                IMAGING

                                                • General Features

                                                  • CT Findings

                                                    • MR Findings

                                                      • Ultrasonographic Findings

                                                        • Angiographic Findings

                                                          • Nuclear Medicine Findings

                                                            • Imaging Recommendations

                                                              DIFFERENTIAL DIAGNOSIS

                                                                PATHOLOGY

                                                                • General Features

                                                                  • Gross Pathologic & Surgical Features

                                                                    • Microscopic Features

                                                                      CLINICAL ISSUES

                                                                      • Presentation

                                                                        • Demographics

                                                                          • Natural History & Prognosis

                                                                            • Treatment

                                                                              DIAGNOSTIC CHECKLIST

                                                                              • Consider

                                                                                • Image Interpretation Pearls

                                                                                  Selected References

                                                                                  1. Alshahrani MA et al: Bilateral adrenal abnormalities: imaging review of different entities. Abdom Radiol (NY). 44(1):154-79, 2019
                                                                                  2. Schieda N et al: Renal and adrenal masses containing fat at MRI: proposed nomenclature by the society of abdominal radiology disease-focused panel on renal cell carcinoma. J Magn Reson Imaging. 49(4):917-26, 2019
                                                                                  3. Decmann Á et al: Adrenal myelolipoma: a comprehensive review. Endocrine. 59(1):7-15, 2018
                                                                                  4. Campbell MJ et al: The radiographically diagnosed adrenal myelolipoma: what do we really know? Endocrine. 58(2):289-94, 2017
                                                                                  5. Farrugia FA et al: Radiology of the adrenal incidentalomas. Review of the literature. Endocr Regul. 51(1):35-51, 2017
                                                                                  6. Littrell LA et al: Extra-adrenal myelolipoma and extramedullary hematopoiesis: imaging features of two similar benign fat-containing presacral masses that may mimic liposarcoma. Eur J Radiol. 93:185-94, 2017
                                                                                  7. Mendiratta-Lala M et al: Adrenal imaging. Endocrinol Metab Clin North Am. 46(3):741-59, 2017
                                                                                  8. Tanner J et al: Case 243: extramedullary hematopoiesis in an adrenal myelolipoma. Radiology. 284(1):292-6, 2017
                                                                                  9. Shaaban AM et al: Fat-containing retroperitoneal lesions: imaging characteristics, localization, and differential diagnosis. Radiographics. 36(3):710-34, 2016
                                                                                  10. Yin L et al: A 10-year single-center experience with surgical management of adrenal myelolipoma. J Endourol. 28(2):252-5, 2014
                                                                                  11. Schieda N et al: Pitfalls of adrenal imaging with chemical shift MRI. Clin Radiol. 69(11):1186-97, 2014
                                                                                  12. Katabathina VS et al: Adrenal collision tumors and their mimics: multimodality imaging findings. Cancer Imaging. 13(4):602-10, 2013
                                                                                  13. Castinetti F et al: Adrenal myelolipoma: an unusual cause of bilateral highly 18F-FDG-avid adrenal masses. J Clin Endocrinol Metab. 97(8):2577-8, 2012
                                                                                  14. Giacinto J et al: Nonoperative management of adrenal myelolipoma hemorrhage resulting from trauma. Am Surg. 78(11):E463-4, 2012
                                                                                  15. Su HC et al: Adrenal myelolipoma associated with hyperandrogenemia. Int J Urol. 19(11):1026-8, 2012
                                                                                  16. German-Mena E et al: Adrenal myelolipomas in patients with congenital adrenal hyperplasia: review of the literature and a case report. Endocr Pract. 7(3):441-7, 2011
                                                                                  17. Daneshmand S et al: Adrenal myelolipoma: diagnosis and management. Urol J. 3(2):71-4, 2006
                                                                                  18. Kenney PJ et al: Myelolipoma: CT and pathologic features. Radiology. 208(1):87-95, 1998
                                                                                  19. Rao P et al: Imaging and pathologic features of myelolipoma. Radiographics. 17(6):1373-85, 1997
                                                                                  20. Cyran KM et al: Adrenal myelolipoma. AJR Am J Roentgenol. 166(2):395-400, 1996