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Pediatrics
Diagnosis
Gastrointestinal
Normal Pediatric Variants
Age-Related Appearance of Spleen
Age-Related Appearance of Spleen
Ethan A. Smith, MD
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KEY FACTS

  • Imaging

    • Pathology

      TERMINOLOGY

      • Definitions

        • Spleen consists of red pulp & white pulp
          • White pulp: Reticuloendothelial cells organized into lymphoid follicles (or bodies)
          • Red pulp: Vascular sinusoids

      IMAGING

      • CT Findings

        • MR Findings

          • Ultrasonographic Findings

            DIFFERENTIAL DIAGNOSIS

              PATHOLOGY

              • General Features

                DIAGNOSTIC CHECKLIST

                • Image Interpretation Pearls

                  Selected References

                  1. Boehnke MW et al: Imaging features of pathologically proven pediatric splenic masses. Pediatr Radiol. 50(9):1284-92, 2020
                  2. Di Serafino M et al: Ultrasonography of the pediatric spleen: a pictorial essay. J Ultrasound. 22(4):503-12, 2019
                  3. Gale HI et al: Expected sonographic appearance of the spleen in children and young adults with sickle cell disease: An Update. J Ultrasound Med. 35(8):1735-45, 2016
                  4. Kuint RC et al: Sonographic bands of hypoechogenicity in the spleen in children: zebra spleen. AJR Am J Roentgenol. 207(3):648-52, 2016
                  5. Li G et al: The effect of age on apparent diffusion coefficient values in normal spleen: a preliminary study. Clin Radiol. 69(4):e165-7, 2014
                  6. Clark TJ et al: Splenic trauma: pictorial review of contrast-enhanced CT findings. Emerg Radiol. 18(3):227-34, 2011
                  7. Megremis SD et al: Spleen length in childhood with US: normal values based on age, sex, and somatometric parameters. Radiology. 231(1):129-34, 2004
                  8. Donnelly LF et al: Heterogeneous splenic enhancement patterns on spiral CT images in children: minimizing misinterpretation. Radiology. 210(2):493-7, 1999
                  9. Paterson A et al: A pattern-oriented approach to splenic imaging in infants and children. Radiographics. 19(6):1465-85, 1999
                  10. Donnelly LF et al: Normal changes in the MR appearance of the spleen during early childhood. AJR Am J Roentgenol. 166(3):635-9, 1996
                  Related Anatomy
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                  Related Differential Diagnoses
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                  References
                  Tables

                  Tables

                  KEY FACTS

                  • Imaging

                    • Pathology

                      TERMINOLOGY

                      • Definitions

                        • Spleen consists of red pulp & white pulp
                          • White pulp: Reticuloendothelial cells organized into lymphoid follicles (or bodies)
                          • Red pulp: Vascular sinusoids

                      IMAGING

                      • CT Findings

                        • MR Findings

                          • Ultrasonographic Findings

                            DIFFERENTIAL DIAGNOSIS

                              PATHOLOGY

                              • General Features

                                DIAGNOSTIC CHECKLIST

                                • Image Interpretation Pearls

                                  Selected References

                                  1. Boehnke MW et al: Imaging features of pathologically proven pediatric splenic masses. Pediatr Radiol. 50(9):1284-92, 2020
                                  2. Di Serafino M et al: Ultrasonography of the pediatric spleen: a pictorial essay. J Ultrasound. 22(4):503-12, 2019
                                  3. Gale HI et al: Expected sonographic appearance of the spleen in children and young adults with sickle cell disease: An Update. J Ultrasound Med. 35(8):1735-45, 2016
                                  4. Kuint RC et al: Sonographic bands of hypoechogenicity in the spleen in children: zebra spleen. AJR Am J Roentgenol. 207(3):648-52, 2016
                                  5. Li G et al: The effect of age on apparent diffusion coefficient values in normal spleen: a preliminary study. Clin Radiol. 69(4):e165-7, 2014
                                  6. Clark TJ et al: Splenic trauma: pictorial review of contrast-enhanced CT findings. Emerg Radiol. 18(3):227-34, 2011
                                  7. Megremis SD et al: Spleen length in childhood with US: normal values based on age, sex, and somatometric parameters. Radiology. 231(1):129-34, 2004
                                  8. Donnelly LF et al: Heterogeneous splenic enhancement patterns on spiral CT images in children: minimizing misinterpretation. Radiology. 210(2):493-7, 1999
                                  9. Paterson A et al: A pattern-oriented approach to splenic imaging in infants and children. Radiographics. 19(6):1465-85, 1999
                                  10. Donnelly LF et al: Normal changes in the MR appearance of the spleen during early childhood. AJR Am J Roentgenol. 166(3):635-9, 1996