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AHLE
Anne G. Osborn, MD, FACR
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Clinical Issues

          • Diagnostic Checklist

            TERMINOLOGY

            • Abbreviations

              • Acute hemorrhagic leukoencephalitis (AHLE)
            • Synonyms

              • Acute hemorrhagic encephalomyelitis (AHEM)
              • Weston Hurst disease
            • Definitions

              • Hyperacute, fulminant hemorrhagic perivascular demyelinating disorder
                • Usually viral or immunization related
              • May be exceptionally severe form of acute disseminated encephalomyelopathy (ADEM)

            IMAGING

            • General Features

              • CT Findings

                • MR Findings

                  • Imaging Recommendations

                    DIFFERENTIAL DIAGNOSIS

                      PATHOLOGY

                      • Gross Pathologic & Surgical Features

                        • Microscopic Features

                          CLINICAL ISSUES

                          • Presentation

                            • Demographics

                              • Natural History & Prognosis

                                • Treatment

                                  DIAGNOSTIC CHECKLIST

                                  • Consider

                                    • Image Interpretation Pearls

                                      Selected References

                                      1. Goenka A et al: Neurological manifestations of influenza infection in children and adults: results of a National British Surveillance Study. Clin Infect Dis. 58(6):775-84, 2014
                                      2. Jeganathan N et al: Acute hemorrhagic leukoencephalopathy associated with influenza A (H1N1) virus. Neurocrit Care. 19(2):218-21, 2013
                                      3. Gallucci M et al: Pediatric Inflammatory Diseases. Part II: Acute Post-Infectious Immune Disorders. Neuroradiol J. 25(6):702-14, 2012
                                      Related Anatomy
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                                      Related Differential Diagnoses
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                                      References
                                      Tables

                                      Tables

                                      KEY FACTS

                                      • Terminology

                                        • Imaging

                                          • Top Differential Diagnoses

                                            • Clinical Issues

                                              • Diagnostic Checklist

                                                TERMINOLOGY

                                                • Abbreviations

                                                  • Acute hemorrhagic leukoencephalitis (AHLE)
                                                • Synonyms

                                                  • Acute hemorrhagic encephalomyelitis (AHEM)
                                                  • Weston Hurst disease
                                                • Definitions

                                                  • Hyperacute, fulminant hemorrhagic perivascular demyelinating disorder
                                                    • Usually viral or immunization related
                                                  • May be exceptionally severe form of acute disseminated encephalomyelopathy (ADEM)

                                                IMAGING

                                                • General Features

                                                  • CT Findings

                                                    • MR Findings

                                                      • Imaging Recommendations

                                                        DIFFERENTIAL DIAGNOSIS

                                                          PATHOLOGY

                                                          • Gross Pathologic & Surgical Features

                                                            • Microscopic Features

                                                              CLINICAL ISSUES

                                                              • Presentation

                                                                • Demographics

                                                                  • Natural History & Prognosis

                                                                    • Treatment

                                                                      DIAGNOSTIC CHECKLIST

                                                                      • Consider

                                                                        • Image Interpretation Pearls

                                                                          Selected References

                                                                          1. Goenka A et al: Neurological manifestations of influenza infection in children and adults: results of a National British Surveillance Study. Clin Infect Dis. 58(6):775-84, 2014
                                                                          2. Jeganathan N et al: Acute hemorrhagic leukoencephalopathy associated with influenza A (H1N1) virus. Neurocrit Care. 19(2):218-21, 2013
                                                                          3. Gallucci M et al: Pediatric Inflammatory Diseases. Part II: Acute Post-Infectious Immune Disorders. Neuroradiol J. 25(6):702-14, 2012