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Amyloidosis, Airways
Jeffrey P. Kanne, MD
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Pathology

          • Clinical Issues

            TERMINOLOGY

            • Synonyms

              • Airway amyloidosis
            • Definitions

              • Focal or diffuse submucosal deposition of amyloid in tracheobronchial tree
                • Characterized by amyloid light chain (AL) protein

            IMAGING

            • General Features

              • Radiographic Findings

                • CT Findings

                  • MR Findings

                    • Nuclear Medicine Findings

                      • Imaging Recommendations

                        DIFFERENTIAL DIAGNOSIS

                          PATHOLOGY

                          • General Features

                            • Gross Pathologic & Surgical Features

                              • Microscopic Features

                                CLINICAL ISSUES

                                • Presentation

                                  • Demographics

                                    • Natural History & Prognosis

                                      • Treatment

                                        DIAGNOSTIC CHECKLIST

                                        • Image Interpretation Pearls

                                          Selected References

                                          1. Chung JH et al: CT of diffuse tracheal diseases. AJR Am J Roentgenol. 196(3):W240-6, 2011
                                          2. Gilad R et al: Severe diffuse systemic amyloidosis with involvement of the pharynx, larynx, and trachea: CT and MR findings. AJNR Am J Neuroradiol. 28(8):1557-8, 2007
                                          3. Neben-Wittich MA et al: External beam radiation therapy for tracheobronchial amyloidosis. Chest. 132(1):262-7, 2007
                                          4. Aylwin AC et al: Imaging appearance of thoracic amyloidosis. J Thorac Imaging. 20(1):41-6, 2005
                                          5. Dahl KA et al: Tracheobronchial amyloidosis: a surgical disease with long-term consequences. J Thorac Cardiovasc Surg. 128(5):789-92, 2004
                                          6. Gibbaoui H et al: A case of primary diffuse tracheobronchial amyloidosis. Ann Thorac Surg. 77(5):1832-4, 2004
                                          7. Toyoda M et al: Tracheobronchial AL amyloidosis: histologic, immunohistochemical, ultrastructural, and immunoelectron microscopic observations. Hum Pathol. 24(9):970-6, 1993
                                          Related Anatomy
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                                          Related Differential Diagnoses
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                                          References
                                          Tables

                                          Tables

                                          KEY FACTS

                                          • Terminology

                                            • Imaging

                                              • Top Differential Diagnoses

                                                • Pathology

                                                  • Clinical Issues

                                                    TERMINOLOGY

                                                    • Synonyms

                                                      • Airway amyloidosis
                                                    • Definitions

                                                      • Focal or diffuse submucosal deposition of amyloid in tracheobronchial tree
                                                        • Characterized by amyloid light chain (AL) protein

                                                    IMAGING

                                                    • General Features

                                                      • Radiographic Findings

                                                        • CT Findings

                                                          • MR Findings

                                                            • Nuclear Medicine Findings

                                                              • Imaging Recommendations

                                                                DIFFERENTIAL DIAGNOSIS

                                                                  PATHOLOGY

                                                                  • General Features

                                                                    • Gross Pathologic & Surgical Features

                                                                      • Microscopic Features

                                                                        CLINICAL ISSUES

                                                                        • Presentation

                                                                          • Demographics

                                                                            • Natural History & Prognosis

                                                                              • Treatment

                                                                                DIAGNOSTIC CHECKLIST

                                                                                • Image Interpretation Pearls

                                                                                  Selected References

                                                                                  1. Chung JH et al: CT of diffuse tracheal diseases. AJR Am J Roentgenol. 196(3):W240-6, 2011
                                                                                  2. Gilad R et al: Severe diffuse systemic amyloidosis with involvement of the pharynx, larynx, and trachea: CT and MR findings. AJNR Am J Neuroradiol. 28(8):1557-8, 2007
                                                                                  3. Neben-Wittich MA et al: External beam radiation therapy for tracheobronchial amyloidosis. Chest. 132(1):262-7, 2007
                                                                                  4. Aylwin AC et al: Imaging appearance of thoracic amyloidosis. J Thorac Imaging. 20(1):41-6, 2005
                                                                                  5. Dahl KA et al: Tracheobronchial amyloidosis: a surgical disease with long-term consequences. J Thorac Cardiovasc Surg. 128(5):789-92, 2004
                                                                                  6. Gibbaoui H et al: A case of primary diffuse tracheobronchial amyloidosis. Ann Thorac Surg. 77(5):1832-4, 2004
                                                                                  7. Toyoda M et al: Tracheobronchial AL amyloidosis: histologic, immunohistochemical, ultrastructural, and immunoelectron microscopic observations. Hum Pathol. 24(9):970-6, 1993