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Anaplastic Thyroid Carcinoma
Eunice Y. L. Dai, MBBS, FRCR; K. T. Wong, MBChB, FRCR; Anil T. Ahuja, MD, FRCR
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KEY FACTS

  • Imaging

    • Top Differential Diagnoses

      • Diagnostic Checklist

        TERMINOLOGY

        • Abbreviations

          • Anaplastic thyroid carcinoma (ATCa)
        • Synonyms

          • Undifferentiated thyroid carcinoma
        • Definitions

          • Lethal thyroid malignancy from transformation of either differentiated thyroid carcinoma (DTCa) or multinodular goiter (MNG)

        IMAGING

        • General Features

          • Ultrasonographic Findings

            • Radiographic Findings

              • CT Findings

                • MR Findings

                  • Nuclear Medicine Findings

                    • Imaging Recommendations

                      DIFFERENTIAL DIAGNOSIS

                        PATHOLOGY

                        • General Features

                          • Staging, Grading, & Classification

                            • Gross Pathologic & Surgical Features

                              CLINICAL ISSUES

                              • Presentation

                                • Demographics

                                  • Natural History & Prognosis

                                    • Treatment

                                      DIAGNOSTIC CHECKLIST

                                      • Consider

                                        • Image Interpretation Pearls

                                          Selected References

                                          1. Ahmed S et al: Imaging of anaplastic thyroid carcinoma. AJNR Am J Neuroradiol. ePub, 2017
                                          2. Hahn SY et al: Description and comparison of the sonographic characteristics of poorly differentiated thyroid carcinoma and anaplastic thyroid carcinoma. J Ultrasound Med. 35(9):1873-9, 2016
                                          3. Wong KT et al: Ultrasound of Thyroid Cancer. Cancer Imaging. 5: 157-66, 2005
                                          4. Harnsberger HR et al: Diagnostic Imaging: Head & Neck. 1st ed. Salt Lake City: Amirsys. III-11-32-35, 2004
                                          5. Ahuja AT et al: Imaging in Head & Neck Cancer: A Practical Approach. London: Greenwich Medical Media. 143-65, 2003
                                          6. Pasieka JL: Anaplastic thyroid cancer. Curr Opin Oncol. 15(1):78-83, 2003
                                          7. Sherman SI: Thyroid carcinoma. Lancet. 361(9356):501-11, 2003
                                          8. Wiseman SM et al: Anaplastic transformation of thyroid cancer: review of clinical, pathologic, and molecular evidence provides new insights into disease biology and future therapy. Head Neck. 25(8):662-70, 2003
                                          9. Ishikawa H et al: Comparison of primary thyroid lymphoma with anaplastic thyroid carcinoma on computed tomographic imaging. Radiat Med. 20(1):9-15, 2002
                                          10. Stanley MW: Selected problems in fine needle aspiration of head and neck masses. Mod Pathol. 15(3):342-50, 2002
                                          11. Vini L et al: Management of thyroid cancer. Lancet Oncol. 3(7):407-14, 2002
                                          12. Lind P et al: The role of F-18FDG PET in thyroid cancer. Acta Med Austriaca. 27(2):38-41, 2000
                                          13. Takashima S et al: CT evaluation of anaplastic thyroid carcinoma. AJNR Am J Neuroradiol. 11(2):361-7, 1990
                                          Related Anatomy
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                                          Related Differential Diagnoses
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                                          References
                                          Tables

                                          Tables

                                          KEY FACTS

                                          • Imaging

                                            • Top Differential Diagnoses

                                              • Diagnostic Checklist

                                                TERMINOLOGY

                                                • Abbreviations

                                                  • Anaplastic thyroid carcinoma (ATCa)
                                                • Synonyms

                                                  • Undifferentiated thyroid carcinoma
                                                • Definitions

                                                  • Lethal thyroid malignancy from transformation of either differentiated thyroid carcinoma (DTCa) or multinodular goiter (MNG)

                                                IMAGING

                                                • General Features

                                                  • Ultrasonographic Findings

                                                    • Radiographic Findings

                                                      • CT Findings

                                                        • MR Findings

                                                          • Nuclear Medicine Findings

                                                            • Imaging Recommendations

                                                              DIFFERENTIAL DIAGNOSIS

                                                                PATHOLOGY

                                                                • General Features

                                                                  • Staging, Grading, & Classification

                                                                    • Gross Pathologic & Surgical Features

                                                                      CLINICAL ISSUES

                                                                      • Presentation

                                                                        • Demographics

                                                                          • Natural History & Prognosis

                                                                            • Treatment

                                                                              DIAGNOSTIC CHECKLIST

                                                                              • Consider

                                                                                • Image Interpretation Pearls

                                                                                  Selected References

                                                                                  1. Ahmed S et al: Imaging of anaplastic thyroid carcinoma. AJNR Am J Neuroradiol. ePub, 2017
                                                                                  2. Hahn SY et al: Description and comparison of the sonographic characteristics of poorly differentiated thyroid carcinoma and anaplastic thyroid carcinoma. J Ultrasound Med. 35(9):1873-9, 2016
                                                                                  3. Wong KT et al: Ultrasound of Thyroid Cancer. Cancer Imaging. 5: 157-66, 2005
                                                                                  4. Harnsberger HR et al: Diagnostic Imaging: Head & Neck. 1st ed. Salt Lake City: Amirsys. III-11-32-35, 2004
                                                                                  5. Ahuja AT et al: Imaging in Head & Neck Cancer: A Practical Approach. London: Greenwich Medical Media. 143-65, 2003
                                                                                  6. Pasieka JL: Anaplastic thyroid cancer. Curr Opin Oncol. 15(1):78-83, 2003
                                                                                  7. Sherman SI: Thyroid carcinoma. Lancet. 361(9356):501-11, 2003
                                                                                  8. Wiseman SM et al: Anaplastic transformation of thyroid cancer: review of clinical, pathologic, and molecular evidence provides new insights into disease biology and future therapy. Head Neck. 25(8):662-70, 2003
                                                                                  9. Ishikawa H et al: Comparison of primary thyroid lymphoma with anaplastic thyroid carcinoma on computed tomographic imaging. Radiat Med. 20(1):9-15, 2002
                                                                                  10. Stanley MW: Selected problems in fine needle aspiration of head and neck masses. Mod Pathol. 15(3):342-50, 2002
                                                                                  11. Vini L et al: Management of thyroid cancer. Lancet Oncol. 3(7):407-14, 2002
                                                                                  12. Lind P et al: The role of F-18FDG PET in thyroid cancer. Acta Med Austriaca. 27(2):38-41, 2000
                                                                                  13. Takashima S et al: CT evaluation of anaplastic thyroid carcinoma. AJNR Am J Neuroradiol. 11(2):361-7, 1990