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KEY FACTS
Imaging
Top Differential Diagnoses
Pathology
Clinical Issues
Diagnostic Checklist
TERMINOLOGY
Abbreviations
- Aneurysmal bone cyst (ABC)
Definitions
- Expansile benign neoplasm containing thin-walled, blood-filled cavities
IMAGING
General Features
Radiographic Findings
CT Findings
MR Findings
Angiographic Findings
Nuclear Medicine Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Gross Pathologic & Surgical Features
Microscopic Features
Genetics
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Image Interpretation Pearls
Selected References
- Bazzocchi A et al: Fluid-fluid levels in aneurysmal bone cysts. J Pediatr. 204:317, 2018
- Girolami M et al: Do multiple fluid-fluid levels on MRI always reveal primary benign aneurysmal bone cyst? J Neurosurg Sci. 62(2):234-36, 2018
- Palmerini E et al: Denosumab in patients with aneurysmal bone cysts: a case series with preliminary results. Tumori. 104(5):344-51, 2018
- Samir Barakat A et al: Early recurrence of a solid variant of aneurysmal bone cyst in a young child after resection: technique and literature review and two-year follow-up after corpectomy. J Am Acad Orthop Surg. 26(10):369-75, 2018
- Protas M et al: Cervical spine aneurysmal bone cysts in the pediatric population: a systematic review of the literature. Pediatr Neurosurg. 52(4):219-224, 2017
- Charest-Morin R et al: Benign tumors of the spine: has new chemotherapy and interventional radiology changed the treatment paradigm? Spine (Phila Pa 1976). 41 Suppl 20:S178-85, 2016
- Dubory A et al: Interest of Denosumab for the treatment of giant-cells tumors and aneurysmal bone cysts of the spine. About nine cases. Spine (Phila Pa 1976). 41(11):E654-60, 2016
- Oliveira AM et al: USP6-induced neoplasms: the biologic spectrum of aneurysmal bone cyst and nodular fasciitis. Hum Pathol. 45(1):1-11, 2014
- Amendola L et al: Aneurysmal bone cyst of the mobile spine: the therapeutic role of embolization. Eur Spine J. 22(3):533-41, 2013
- Zileli M et al: Aneurysmal bone cysts of the spine. Eur Spine J. 22(3):593-601, 2013
- Oliveira AM et al: The TRE17/USP6 oncogene: a riddle wrapped in a mystery inside an enigma. Front Biosci (Schol Ed). 4:321-4, 2012
- Ye Y et al: TRE17/USP6 oncogene translocated in aneurysmal bone cyst induces matrix metalloproteinase production via activation of NF-kappaB. Oncogene. 29(25):3619-29, 2010
- Brastianos P et al: Aneurysmal bone cysts of the sacrum: a report of ten cases and review of the literature. Iowa Orthop J. 29:74-8, 2009
- Mankin HJ et al: Aneurysmal bone cyst: a review of 150 patients. J Clin Oncol. 23(27):6756-62, 2005
- Garneti N et al: Cervical spondyloptosis caused by an aneurysmal bone cyst: a case report. Spine. 28(4):E68-70, 2003
- Lomasney LM et al: Fibrous dysplasia complicated by aneurysmal bone cyst formation affecting multiple cervical vertebrae. Skeletal Radiol. 32(9):533-6, 2003
- Pogoda P et al: Aneurysmal bone cysts of the sacrum. Clinical report and review of the literature. Arch Orthop Trauma Surg. 123(5):247-51, 2003
- Chan MS et al: Spinal aneurysmal bone cyst causing acute cord compression without vertebral collapse: CT and MRI findings. Pediatr Radiol. 32(8):601-4, 2002
- Lam CH et al: Nonteratomatous tumors in the pediatric sacral region. Spine. 27(11):E284-7, 2002
- Boriani S et al: Aneurysmal bone cyst of the mobile spine: report on 41 cases. Spine. 26(1):27-35, 2001
- Papagelopoulos PJ et al: Treatment of aneurysmal bone cysts of the pelvis and sacrum. J Bone Joint Surg Am. 83-A(11):1674-81, 2001
- Bush CH et al: Treatment of an aneurysmal bone cyst of the spine by radionuclide ablation. AJNR Am J Neuroradiol. 21(3):592-4, 2000
- DiCaprio MR et al: Aneurysmal bone cyst of the spine with familial incidence. Spine. 25(12):1589-92, 2000
- Ozaki T et al: Aneurysmal bone cysts of the spine. Arch Orthop Trauma Surg. 119(3-4):159-62, 1999
- de Kleuver M et al: Aneurysmal bone cyst of the spine: 31 cases and the importance of the surgical approach. J Pediatr Orthop B. 7(4):286-92, 1998
- Papagelopoulos PJ et al: Aneurysmal bone cyst of the spine. Management and outcome. Spine. 23(5):621-8, 1998
- Murphey MD et al: From the archives of the AFIP. Primary tumors of the spine: radiologic pathologic correlation. Radiographics. 16(5):1131-58, 1996
- Koci TM et al: Aneurysmal bone cyst of the thoracic spine: evolution after particulate embolization. AJNR Am J Neuroradiol. 16(4 Suppl):857-60, 1995
- Kransdorf MJ et al: Aneurysmal bone cyst: concept, controversy, clinical presentation, and imaging. AJR Am J Roentgenol. 164(3):573-80, 1995
Related Anatomy
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References
Tables
Tables
KEY FACTS
Imaging
Top Differential Diagnoses
Pathology
Clinical Issues
Diagnostic Checklist
TERMINOLOGY
Abbreviations
- Aneurysmal bone cyst (ABC)
Definitions
- Expansile benign neoplasm containing thin-walled, blood-filled cavities
IMAGING
General Features
Radiographic Findings
CT Findings
MR Findings
Angiographic Findings
Nuclear Medicine Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Gross Pathologic & Surgical Features
Microscopic Features
Genetics
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Image Interpretation Pearls
Selected References
- Bazzocchi A et al: Fluid-fluid levels in aneurysmal bone cysts. J Pediatr. 204:317, 2018
- Girolami M et al: Do multiple fluid-fluid levels on MRI always reveal primary benign aneurysmal bone cyst? J Neurosurg Sci. 62(2):234-36, 2018
- Palmerini E et al: Denosumab in patients with aneurysmal bone cysts: a case series with preliminary results. Tumori. 104(5):344-51, 2018
- Samir Barakat A et al: Early recurrence of a solid variant of aneurysmal bone cyst in a young child after resection: technique and literature review and two-year follow-up after corpectomy. J Am Acad Orthop Surg. 26(10):369-75, 2018
- Protas M et al: Cervical spine aneurysmal bone cysts in the pediatric population: a systematic review of the literature. Pediatr Neurosurg. 52(4):219-224, 2017
- Charest-Morin R et al: Benign tumors of the spine: has new chemotherapy and interventional radiology changed the treatment paradigm? Spine (Phila Pa 1976). 41 Suppl 20:S178-85, 2016
- Dubory A et al: Interest of Denosumab for the treatment of giant-cells tumors and aneurysmal bone cysts of the spine. About nine cases. Spine (Phila Pa 1976). 41(11):E654-60, 2016
- Oliveira AM et al: USP6-induced neoplasms: the biologic spectrum of aneurysmal bone cyst and nodular fasciitis. Hum Pathol. 45(1):1-11, 2014
- Amendola L et al: Aneurysmal bone cyst of the mobile spine: the therapeutic role of embolization. Eur Spine J. 22(3):533-41, 2013
- Zileli M et al: Aneurysmal bone cysts of the spine. Eur Spine J. 22(3):593-601, 2013
- Oliveira AM et al: The TRE17/USP6 oncogene: a riddle wrapped in a mystery inside an enigma. Front Biosci (Schol Ed). 4:321-4, 2012
- Ye Y et al: TRE17/USP6 oncogene translocated in aneurysmal bone cyst induces matrix metalloproteinase production via activation of NF-kappaB. Oncogene. 29(25):3619-29, 2010
- Brastianos P et al: Aneurysmal bone cysts of the sacrum: a report of ten cases and review of the literature. Iowa Orthop J. 29:74-8, 2009
- Mankin HJ et al: Aneurysmal bone cyst: a review of 150 patients. J Clin Oncol. 23(27):6756-62, 2005
- Garneti N et al: Cervical spondyloptosis caused by an aneurysmal bone cyst: a case report. Spine. 28(4):E68-70, 2003
- Lomasney LM et al: Fibrous dysplasia complicated by aneurysmal bone cyst formation affecting multiple cervical vertebrae. Skeletal Radiol. 32(9):533-6, 2003
- Pogoda P et al: Aneurysmal bone cysts of the sacrum. Clinical report and review of the literature. Arch Orthop Trauma Surg. 123(5):247-51, 2003
- Chan MS et al: Spinal aneurysmal bone cyst causing acute cord compression without vertebral collapse: CT and MRI findings. Pediatr Radiol. 32(8):601-4, 2002
- Lam CH et al: Nonteratomatous tumors in the pediatric sacral region. Spine. 27(11):E284-7, 2002
- Boriani S et al: Aneurysmal bone cyst of the mobile spine: report on 41 cases. Spine. 26(1):27-35, 2001
- Papagelopoulos PJ et al: Treatment of aneurysmal bone cysts of the pelvis and sacrum. J Bone Joint Surg Am. 83-A(11):1674-81, 2001
- Bush CH et al: Treatment of an aneurysmal bone cyst of the spine by radionuclide ablation. AJNR Am J Neuroradiol. 21(3):592-4, 2000
- DiCaprio MR et al: Aneurysmal bone cyst of the spine with familial incidence. Spine. 25(12):1589-92, 2000
- Ozaki T et al: Aneurysmal bone cysts of the spine. Arch Orthop Trauma Surg. 119(3-4):159-62, 1999
- de Kleuver M et al: Aneurysmal bone cyst of the spine: 31 cases and the importance of the surgical approach. J Pediatr Orthop B. 7(4):286-92, 1998
- Papagelopoulos PJ et al: Aneurysmal bone cyst of the spine. Management and outcome. Spine. 23(5):621-8, 1998
- Murphey MD et al: From the archives of the AFIP. Primary tumors of the spine: radiologic pathologic correlation. Radiographics. 16(5):1131-58, 1996
- Koci TM et al: Aneurysmal bone cyst of the thoracic spine: evolution after particulate embolization. AJNR Am J Neuroradiol. 16(4 Suppl):857-60, 1995
- Kransdorf MJ et al: Aneurysmal bone cyst: concept, controversy, clinical presentation, and imaging. AJR Am J Roentgenol. 164(3):573-80, 1995
