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Anorexia
B.J. Manaster, MD, PhD, FACR
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KEY FACTS

  • Terminology

    • Imaging

      • Clinical Issues

        TERMINOLOGY

        • Definitions

          • Eating disorder that involves limiting amount of food intake, resulting in starvation
            • Osteoporosis and its consequent bone fragility
              • 7x ↑ in fracture risk; may persist despite recovery
              • Greater deficit in bone mineral density if onset of anorexia during adolescence
            • Reduced muscle mass
            • Serous atrophy associated with true starvation
              • Depletion of both red and yellow marrow elements

        IMAGING

        • Radiographic Findings

          • CT Findings

            • MR Findings

              Selected References

              1. Bachmann KN et al: Vertebral strength and estimated fracture risk across the BMI spectrum in women. J Bone Miner Res. ePub, 2015
              2. Misra M et al: Anorexia nervosa and bone. J Endocrinol. 221(3):R163-76, 2014
              3. Veronese N et al: Vitamin D status in anorexia nervosa: A meta-analysis. Int J Eat Disord. ePub, 2014
              4. Bredella MA et al: Distal radius in adolescent girls with anorexia nervosa: trabecular structure analysis with high-resolution flat-panel volume CT. Radiology. 249(3):938-46, 2008
              5. Galusca B et al: Constitutional thinness: unusual human phenotype of low bone quality. J Clin Endocrinol Metab. 93(1):110-7, 2008
              6. Polito A et al: Body composition changes in anorexia nervosa. Eur J Clin Nutr. 52(9):655-62, 1998
              Related Anatomy
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              Related Differential Diagnoses
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              References
              Tables

              Tables

              KEY FACTS

              • Terminology

                • Imaging

                  • Clinical Issues

                    TERMINOLOGY

                    • Definitions

                      • Eating disorder that involves limiting amount of food intake, resulting in starvation
                        • Osteoporosis and its consequent bone fragility
                          • 7x ↑ in fracture risk; may persist despite recovery
                          • Greater deficit in bone mineral density if onset of anorexia during adolescence
                        • Reduced muscle mass
                        • Serous atrophy associated with true starvation
                          • Depletion of both red and yellow marrow elements

                    IMAGING

                    • Radiographic Findings

                      • CT Findings

                        • MR Findings

                          Selected References

                          1. Bachmann KN et al: Vertebral strength and estimated fracture risk across the BMI spectrum in women. J Bone Miner Res. ePub, 2015
                          2. Misra M et al: Anorexia nervosa and bone. J Endocrinol. 221(3):R163-76, 2014
                          3. Veronese N et al: Vitamin D status in anorexia nervosa: A meta-analysis. Int J Eat Disord. ePub, 2014
                          4. Bredella MA et al: Distal radius in adolescent girls with anorexia nervosa: trabecular structure analysis with high-resolution flat-panel volume CT. Radiology. 249(3):938-46, 2008
                          5. Galusca B et al: Constitutional thinness: unusual human phenotype of low bone quality. J Clin Endocrinol Metab. 93(1):110-7, 2008
                          6. Polito A et al: Body composition changes in anorexia nervosa. Eur J Clin Nutr. 52(9):655-62, 1998