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Antiphospholipid Antibody Syndrome
Jeffrey S. Anderson, MD, PhD
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Pathology

          • Clinical Issues

            • Diagnostic Checklist

              TERMINOLOGY

              • Abbreviations

                • Antiphospholipid antibody syndrome (APS)
              • Definitions

                • Multisystem disorder characterized by
                  • Thromboses, early strokes
                  • Cognitive dysfunction
                  • Pregnancy loss

              IMAGING

              • General Features

                • Imaging Recommendations

                  • CT Findings

                    • MR Findings

                      • Ultrasonographic Findings

                        DIFFERENTIAL DIAGNOSIS

                          PATHOLOGY

                          • General Features

                            • Staging, Grading, & Classification

                              CLINICAL ISSUES

                              • Presentation

                                • Demographics

                                  • Natural History & Prognosis

                                    • Treatment

                                      DIAGNOSTIC CHECKLIST

                                      • Image Interpretation Pearls

                                        • Reporting Tips

                                          Selected References

                                          1. Giannakopoulos B et al: Current concepts on the pathogenesis of the antiphospholipid syndrome. Blood. 109(2):422-30, 2007
                                          2. Lim W et al: Antiphospholipid antibiodies: a critical review of the literature. Curr Opin Hematol. 14(5):494-9, 2007
                                          3. Miyakis S et al: International consensus statement on an update of the classification criteria for definite antiphospholipid syndrome (APS). J Thromb Haemost. 2006 Feb;4(2):295-306. PubMed PMID: 16420554. os PG, Krilis SA. International consensus statement on an update of the classification criteria for definite antiphospholipid syndrome (APS). J Thromb Haemost. 4(2):295-306, 2006
                                          4. Tektonidou MG et al: Cognitive deficits in patients with antiphospholipid syndrome: association with clinical, laboratory, and brain magnetic resonance imaging findings. Arch Intern Med. 166(20):2278-84, 2006
                                          5. Gómez-Puerta JA et al: Dementia associated with the antiphospholipid syndrome: clinical and radiological characteristics of 30 patients. Rheumatology (Oxford). 44(1):95-9, 2005
                                          6. Katzav A et al: CNS dysfunction in the antiphospholipid syndrome. Lupus. 12(12):903-7, 2003
                                          Related Anatomy
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                                          Related Differential Diagnoses
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                                          References
                                          Tables

                                          Tables

                                          KEY FACTS

                                          • Terminology

                                            • Imaging

                                              • Top Differential Diagnoses

                                                • Pathology

                                                  • Clinical Issues

                                                    • Diagnostic Checklist

                                                      TERMINOLOGY

                                                      • Abbreviations

                                                        • Antiphospholipid antibody syndrome (APS)
                                                      • Definitions

                                                        • Multisystem disorder characterized by
                                                          • Thromboses, early strokes
                                                          • Cognitive dysfunction
                                                          • Pregnancy loss

                                                      IMAGING

                                                      • General Features

                                                        • Imaging Recommendations

                                                          • CT Findings

                                                            • MR Findings

                                                              • Ultrasonographic Findings

                                                                DIFFERENTIAL DIAGNOSIS

                                                                  PATHOLOGY

                                                                  • General Features

                                                                    • Staging, Grading, & Classification

                                                                      CLINICAL ISSUES

                                                                      • Presentation

                                                                        • Demographics

                                                                          • Natural History & Prognosis

                                                                            • Treatment

                                                                              DIAGNOSTIC CHECKLIST

                                                                              • Image Interpretation Pearls

                                                                                • Reporting Tips

                                                                                  Selected References

                                                                                  1. Giannakopoulos B et al: Current concepts on the pathogenesis of the antiphospholipid syndrome. Blood. 109(2):422-30, 2007
                                                                                  2. Lim W et al: Antiphospholipid antibiodies: a critical review of the literature. Curr Opin Hematol. 14(5):494-9, 2007
                                                                                  3. Miyakis S et al: International consensus statement on an update of the classification criteria for definite antiphospholipid syndrome (APS). J Thromb Haemost. 2006 Feb;4(2):295-306. PubMed PMID: 16420554. os PG, Krilis SA. International consensus statement on an update of the classification criteria for definite antiphospholipid syndrome (APS). J Thromb Haemost. 4(2):295-306, 2006
                                                                                  4. Tektonidou MG et al: Cognitive deficits in patients with antiphospholipid syndrome: association with clinical, laboratory, and brain magnetic resonance imaging findings. Arch Intern Med. 166(20):2278-84, 2006
                                                                                  5. Gómez-Puerta JA et al: Dementia associated with the antiphospholipid syndrome: clinical and radiological characteristics of 30 patients. Rheumatology (Oxford). 44(1):95-9, 2005
                                                                                  6. Katzav A et al: CNS dysfunction in the antiphospholipid syndrome. Lupus. 12(12):903-7, 2003