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Aortic Regurgitation
Gudrun Feuchtner, MD
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Clinical Issues

          • Diagnostic Checklist

            TERMINOLOGY

            • Abbreviations

              • Aortic regurgitation (AR)
            • Synonyms

              • Aortic insufficiency
            • Definitions

              • Incomplete closure of cusps during diastole leading to retrograde blood flow into left ventricle (LV)

            IMAGING

            • General Features

              • Radiographic Findings

                • CT Findings

                  • MR Findings

                    • Echocardiographic Findings

                      • Angiographic Findings

                        • Imaging Recommendations

                          DIFFERENTIAL DIAGNOSIS

                            PATHOLOGY

                            • General Features

                              • Staging, Grading, & Classification

                                CLINICAL ISSUES

                                • Presentation

                                  • Demographics

                                    • Natural History & Prognosis

                                      • Treatment

                                        DIAGNOSTIC CHECKLIST

                                        • Consider

                                          • Image Interpretation Pearls

                                            Selected References

                                            1. Lee JC et al: Evaluation of aortic regurgitation with cardiac magnetic resonance imaging: a systematic review. Heart. 104(2):103-10, 2018
                                            2. Harris AW et al: Cardiac magnetic resonance imaging versus transthoracic echocardiography for prediction of outcomes in chronic aortic or mitral regurgitation. Am J Cardiol. 119(7):1074-81, 2017
                                            3. Myerson SG et al: Aortic regurgitation quantification using cardiovascular magnetic resonance: association with clinical outcome. Circulation. 126(12):1452-60, 2012
                                            4. Bolen MA et al: Cardiac MR assessment of aortic regurgitation: holodiastolic flow reversal in the descending aorta helps stratify severity. Radiology. 260(1):98-104, 2011
                                            5. Zeb I et al: Detection of aortic regurgitation with 64-slice multidetector computed tomography (MDCT). Acad Radiol. 17(8):1006-11, 2010
                                            6. Alkadhi H et al: Aortic regurgitation: assessment with 64-section CT. Radiology. 245(1):111-21, 2007
                                            7. Jassal DS et al: 64-slice multidetector computed tomography (MDCT) for detection of aortic regurgitation and quantification of severity. Invest Radiol. 42(7):507-12, 2007
                                            8. Feuchtner GM et al: Diagnostic performance of MDCT for detecting aortic valve regurgitation. AJR Am J Roentgenol. 186(6):1676-81, 2006
                                            9. Braunwald E: Valvular heart disease. In Braunwald E: Heart Disease: A Textbook of Cardiovascular Medicine. 6th ed. Philadelphia: W. B. Saunders, 2001
                                            10. Gelfand EV et al: Severity of mitral and aortic regurgitation as assessed by cardiovascular magnetic resonance: optimizing correlation with Doppler echocardiography. J Cardiovasc Magn Reson. 8(3):503-7, 2006
                                            11. Singh JP et al: Prevalence and clinical determinants of mitral, tricuspid, and aortic regurgitation (the Framingham Heart Study). Am J Cardiol. 83(6):897-902, 1999
                                            Related Anatomy
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                                            Related Differential Diagnoses
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                                            References
                                            Tables

                                            Tables

                                            KEY FACTS

                                            • Terminology

                                              • Imaging

                                                • Top Differential Diagnoses

                                                  • Clinical Issues

                                                    • Diagnostic Checklist

                                                      TERMINOLOGY

                                                      • Abbreviations

                                                        • Aortic regurgitation (AR)
                                                      • Synonyms

                                                        • Aortic insufficiency
                                                      • Definitions

                                                        • Incomplete closure of cusps during diastole leading to retrograde blood flow into left ventricle (LV)

                                                      IMAGING

                                                      • General Features

                                                        • Radiographic Findings

                                                          • CT Findings

                                                            • MR Findings

                                                              • Echocardiographic Findings

                                                                • Angiographic Findings

                                                                  • Imaging Recommendations

                                                                    DIFFERENTIAL DIAGNOSIS

                                                                      PATHOLOGY

                                                                      • General Features

                                                                        • Staging, Grading, & Classification

                                                                          CLINICAL ISSUES

                                                                          • Presentation

                                                                            • Demographics

                                                                              • Natural History & Prognosis

                                                                                • Treatment

                                                                                  DIAGNOSTIC CHECKLIST

                                                                                  • Consider

                                                                                    • Image Interpretation Pearls

                                                                                      Selected References

                                                                                      1. Lee JC et al: Evaluation of aortic regurgitation with cardiac magnetic resonance imaging: a systematic review. Heart. 104(2):103-10, 2018
                                                                                      2. Harris AW et al: Cardiac magnetic resonance imaging versus transthoracic echocardiography for prediction of outcomes in chronic aortic or mitral regurgitation. Am J Cardiol. 119(7):1074-81, 2017
                                                                                      3. Myerson SG et al: Aortic regurgitation quantification using cardiovascular magnetic resonance: association with clinical outcome. Circulation. 126(12):1452-60, 2012
                                                                                      4. Bolen MA et al: Cardiac MR assessment of aortic regurgitation: holodiastolic flow reversal in the descending aorta helps stratify severity. Radiology. 260(1):98-104, 2011
                                                                                      5. Zeb I et al: Detection of aortic regurgitation with 64-slice multidetector computed tomography (MDCT). Acad Radiol. 17(8):1006-11, 2010
                                                                                      6. Alkadhi H et al: Aortic regurgitation: assessment with 64-section CT. Radiology. 245(1):111-21, 2007
                                                                                      7. Jassal DS et al: 64-slice multidetector computed tomography (MDCT) for detection of aortic regurgitation and quantification of severity. Invest Radiol. 42(7):507-12, 2007
                                                                                      8. Feuchtner GM et al: Diagnostic performance of MDCT for detecting aortic valve regurgitation. AJR Am J Roentgenol. 186(6):1676-81, 2006
                                                                                      9. Braunwald E: Valvular heart disease. In Braunwald E: Heart Disease: A Textbook of Cardiovascular Medicine. 6th ed. Philadelphia: W. B. Saunders, 2001
                                                                                      10. Gelfand EV et al: Severity of mitral and aortic regurgitation as assessed by cardiovascular magnetic resonance: optimizing correlation with Doppler echocardiography. J Cardiovasc Magn Reson. 8(3):503-7, 2006
                                                                                      11. Singh JP et al: Prevalence and clinical determinants of mitral, tricuspid, and aortic regurgitation (the Framingham Heart Study). Am J Cardiol. 83(6):897-902, 1999