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Artifacts: Nuclear Medicine
Amy Lynn Conners, MD; Wendie A. Berg, MD, PhD, FACR, FSBI
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KEY FACTS

  • Terminology

    • Top Differential Diagnoses

      • Diagnostic Checklist

        TERMINOLOGY

        • Definitions

          • Artifact: Any physical phenomenon that interferes with image quality or adds structured noise to image; can mimic pathology or interfere with interpretation
          • Imaging devices: All obtain dedicated breast images with stabilization, in positions analogous to mammography (CC and MLO), with additional views as needed
            • Molecular breast imaging (MBI): 2 cadmium-zinc-telluride (CZT)-based semiconductor detectors, ~ 8 millicurie (mCi) injection of Tc-99m sestamibi IV
            • Breast-specific gamma imaging (BSGI): Single sodium iodide (NaI)-based detector and compression paddle, ~ 12-20 mCi injection of Tc-99m sestamibi IV
            • Positron emission mammography (PEM): Coincidence detectors, ~ 2.5-10 mCi injection of F-18 fluorodeoxyglucose (F-18 FDG) IV
              • Fasting 4-6 hours; blood glucose < 140 mg/dL (ideally)
              • Minimum 1 hour circulation time; patient rests quietly

        DIFFERENTIAL DIAGNOSIS

          DIAGNOSTIC CHECKLIST

          • Quality Control: MBI

            • Quality Control: PEM

              Selected References

              1. Odle TG: Breast imaging artifacts. Radiol Technol. 87(1):65M-87M, 2015
              2. Conners AL et al: Gamma camera breast imaging lexicon. AJR Am J Roentgenol. 199(6):W767-74, 2012
              3. MacDonald L et al: Clinical imaging characteristics of the positron emission mammography camera: PEM Flex Solo II. J Nucl Med. 50(10):1666-75, 2009
              4. Berg WA et al: High-resolution fluorodeoxyglucose positron emission tomography with compression ("positron emission mammography") is highly accurate in depicting primary breast cancer. Breast J. 12(4):309-23, 2006
              Related Anatomy
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              Related Differential Diagnoses
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              References
              Tables

              Tables

              KEY FACTS

              • Terminology

                • Top Differential Diagnoses

                  • Diagnostic Checklist

                    TERMINOLOGY

                    • Definitions

                      • Artifact: Any physical phenomenon that interferes with image quality or adds structured noise to image; can mimic pathology or interfere with interpretation
                      • Imaging devices: All obtain dedicated breast images with stabilization, in positions analogous to mammography (CC and MLO), with additional views as needed
                        • Molecular breast imaging (MBI): 2 cadmium-zinc-telluride (CZT)-based semiconductor detectors, ~ 8 millicurie (mCi) injection of Tc-99m sestamibi IV
                        • Breast-specific gamma imaging (BSGI): Single sodium iodide (NaI)-based detector and compression paddle, ~ 12-20 mCi injection of Tc-99m sestamibi IV
                        • Positron emission mammography (PEM): Coincidence detectors, ~ 2.5-10 mCi injection of F-18 fluorodeoxyglucose (F-18 FDG) IV
                          • Fasting 4-6 hours; blood glucose < 140 mg/dL (ideally)
                          • Minimum 1 hour circulation time; patient rests quietly

                    DIFFERENTIAL DIAGNOSIS

                      DIAGNOSTIC CHECKLIST

                      • Quality Control: MBI

                        • Quality Control: PEM

                          Selected References

                          1. Odle TG: Breast imaging artifacts. Radiol Technol. 87(1):65M-87M, 2015
                          2. Conners AL et al: Gamma camera breast imaging lexicon. AJR Am J Roentgenol. 199(6):W767-74, 2012
                          3. MacDonald L et al: Clinical imaging characteristics of the positron emission mammography camera: PEM Flex Solo II. J Nucl Med. 50(10):1666-75, 2009
                          4. Berg WA et al: High-resolution fluorodeoxyglucose positron emission tomography with compression ("positron emission mammography") is highly accurate in depicting primary breast cancer. Breast J. 12(4):309-23, 2006