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KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Pathology
Clinical Issues
Diagnostic Checklist
TERMINOLOGY
Synonyms
- Bronchial asthma
- Airway hyperreactivity
- Reactive airway disease
Definitions
- Not single disease; rather, umbrella term for numerous phenotypes in which normally harmless environmental allergens cause airway hyperresponsiveness due to pathologic immune-mediated host response
- Airway hyperresponsiveness → contraction of bronchial wall smooth muscle & cascade of inflammation → acute, reversible, airway narrowing & airflow obstruction
IMAGING
General Features
Radiographic Findings
CT Findings
MR Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Image Interpretation Pearls
Selected References
- Altes TA et al: Clinical correlates of lung ventilation defects in asthmatic children. J Allergy Clin Immunol. 137(3):789-796.e7, 2016
- Narayanan S et al: Relevance of chest radiography in pediatric inpatients with asthma. J Asthma. 51(7):751-5, 2014
- Szefler SJ et al: Asthma across the ages: knowledge gaps in childhood asthma. J Allergy Clin Immunol. 133(1):3-13; quiz 14, 2014
- Cadman RV et al: Pulmonary 3He magnetic resonance imaging of childhood asthma. J Allergy Clin Immunol. 131(2):369-76.e1-5, 2013
- Ober C et al: The genetics of asthma and allergic disease: a 21st century perspective. Immunol Rev. 242(1):10-30, 2011
- Szefler SJ: Advances in pediatric asthma in 2010: addressing the major issues. J Allergy Clin Immunol. 127(1):102-15, 2011
- Bisgaard H et al: Long-term studies of the natural history of asthma in childhood. J Allergy Clin Immunol. 126(2):187-97; quiz 198-9, 2010
- Bush A et al: Management of severe asthma in children. Lancet. 376(9743):814-25, 2010
- Castro-Rodriguez JA: The Asthma Predictive Index: a very useful tool for predicting asthma in young children. J Allergy Clin Immunol. 126(2):212-6, 2010
- de Groot EP et al: Comorbidities of asthma during childhood: possibly important, yet poorly studied. Eur Respir J. 36(3):671-8, 2010
- Quizon A et al: Special considerations in pediatric asthma. Curr Opin Pharmacol. 10(3):272-5, 2010
Related Anatomy
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Related Differential Diagnoses
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References
Tables
Tables
KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Pathology
Clinical Issues
Diagnostic Checklist
TERMINOLOGY
Synonyms
- Bronchial asthma
- Airway hyperreactivity
- Reactive airway disease
Definitions
- Not single disease; rather, umbrella term for numerous phenotypes in which normally harmless environmental allergens cause airway hyperresponsiveness due to pathologic immune-mediated host response
- Airway hyperresponsiveness → contraction of bronchial wall smooth muscle & cascade of inflammation → acute, reversible, airway narrowing & airflow obstruction
IMAGING
General Features
Radiographic Findings
CT Findings
MR Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Image Interpretation Pearls
Selected References
- Altes TA et al: Clinical correlates of lung ventilation defects in asthmatic children. J Allergy Clin Immunol. 137(3):789-796.e7, 2016
- Narayanan S et al: Relevance of chest radiography in pediatric inpatients with asthma. J Asthma. 51(7):751-5, 2014
- Szefler SJ et al: Asthma across the ages: knowledge gaps in childhood asthma. J Allergy Clin Immunol. 133(1):3-13; quiz 14, 2014
- Cadman RV et al: Pulmonary 3He magnetic resonance imaging of childhood asthma. J Allergy Clin Immunol. 131(2):369-76.e1-5, 2013
- Ober C et al: The genetics of asthma and allergic disease: a 21st century perspective. Immunol Rev. 242(1):10-30, 2011
- Szefler SJ: Advances in pediatric asthma in 2010: addressing the major issues. J Allergy Clin Immunol. 127(1):102-15, 2011
- Bisgaard H et al: Long-term studies of the natural history of asthma in childhood. J Allergy Clin Immunol. 126(2):187-97; quiz 198-9, 2010
- Bush A et al: Management of severe asthma in children. Lancet. 376(9743):814-25, 2010
- Castro-Rodriguez JA: The Asthma Predictive Index: a very useful tool for predicting asthma in young children. J Allergy Clin Immunol. 126(2):212-6, 2010
- de Groot EP et al: Comorbidities of asthma during childhood: possibly important, yet poorly studied. Eur Respir J. 36(3):671-8, 2010
- Quizon A et al: Special considerations in pediatric asthma. Curr Opin Pharmacol. 10(3):272-5, 2010
