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Asthma
Hank Baskin, MD
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Pathology

          • Clinical Issues

            • Diagnostic Checklist

              TERMINOLOGY

              • Synonyms

                • Bronchial asthma
                • Airway hyperreactivity
                • Reactive airway disease
              • Definitions

                • Not single disease; rather, umbrella term for numerous phenotypes in which normally harmless environmental allergens cause airway hyperresponsiveness due to pathologic immune-mediated host response
                • Airway hyperresponsiveness → contraction of bronchial wall smooth muscle & cascade of inflammation → acute, reversible, airway narrowing & airflow obstruction

              IMAGING

              • General Features

                • Radiographic Findings

                  • CT Findings

                    • MR Findings

                      • Imaging Recommendations

                        DIFFERENTIAL DIAGNOSIS

                          PATHOLOGY

                          • General Features

                            • Gross Pathologic & Surgical Features

                              • Microscopic Features

                                CLINICAL ISSUES

                                • Presentation

                                  • Demographics

                                    • Natural History & Prognosis

                                      • Treatment

                                        DIAGNOSTIC CHECKLIST

                                        • Consider

                                          • Image Interpretation Pearls

                                            Selected References

                                            1. Altes TA et al: Clinical correlates of lung ventilation defects in asthmatic children. J Allergy Clin Immunol. 137(3):789-796.e7, 2016
                                            2. Narayanan S et al: Relevance of chest radiography in pediatric inpatients with asthma. J Asthma. 51(7):751-5, 2014
                                            3. Szefler SJ et al: Asthma across the ages: knowledge gaps in childhood asthma. J Allergy Clin Immunol. 133(1):3-13; quiz 14, 2014
                                            4. Cadman RV et al: Pulmonary 3He magnetic resonance imaging of childhood asthma. J Allergy Clin Immunol. 131(2):369-76.e1-5, 2013
                                            5. Ober C et al: The genetics of asthma and allergic disease: a 21st century perspective. Immunol Rev. 242(1):10-30, 2011
                                            6. Szefler SJ: Advances in pediatric asthma in 2010: addressing the major issues. J Allergy Clin Immunol. 127(1):102-15, 2011
                                            7. Bisgaard H et al: Long-term studies of the natural history of asthma in childhood. J Allergy Clin Immunol. 126(2):187-97; quiz 198-9, 2010
                                            8. Bush A et al: Management of severe asthma in children. Lancet. 376(9743):814-25, 2010
                                            9. Castro-Rodriguez JA: The Asthma Predictive Index: a very useful tool for predicting asthma in young children. J Allergy Clin Immunol. 126(2):212-6, 2010
                                            10. de Groot EP et al: Comorbidities of asthma during childhood: possibly important, yet poorly studied. Eur Respir J. 36(3):671-8, 2010
                                            11. Quizon A et al: Special considerations in pediatric asthma. Curr Opin Pharmacol. 10(3):272-5, 2010
                                            Related Anatomy
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                                            Related Differential Diagnoses
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                                            References
                                            Tables

                                            Tables

                                            KEY FACTS

                                            • Terminology

                                              • Imaging

                                                • Top Differential Diagnoses

                                                  • Pathology

                                                    • Clinical Issues

                                                      • Diagnostic Checklist

                                                        TERMINOLOGY

                                                        • Synonyms

                                                          • Bronchial asthma
                                                          • Airway hyperreactivity
                                                          • Reactive airway disease
                                                        • Definitions

                                                          • Not single disease; rather, umbrella term for numerous phenotypes in which normally harmless environmental allergens cause airway hyperresponsiveness due to pathologic immune-mediated host response
                                                          • Airway hyperresponsiveness → contraction of bronchial wall smooth muscle & cascade of inflammation → acute, reversible, airway narrowing & airflow obstruction

                                                        IMAGING

                                                        • General Features

                                                          • Radiographic Findings

                                                            • CT Findings

                                                              • MR Findings

                                                                • Imaging Recommendations

                                                                  DIFFERENTIAL DIAGNOSIS

                                                                    PATHOLOGY

                                                                    • General Features

                                                                      • Gross Pathologic & Surgical Features

                                                                        • Microscopic Features

                                                                          CLINICAL ISSUES

                                                                          • Presentation

                                                                            • Demographics

                                                                              • Natural History & Prognosis

                                                                                • Treatment

                                                                                  DIAGNOSTIC CHECKLIST

                                                                                  • Consider

                                                                                    • Image Interpretation Pearls

                                                                                      Selected References

                                                                                      1. Altes TA et al: Clinical correlates of lung ventilation defects in asthmatic children. J Allergy Clin Immunol. 137(3):789-796.e7, 2016
                                                                                      2. Narayanan S et al: Relevance of chest radiography in pediatric inpatients with asthma. J Asthma. 51(7):751-5, 2014
                                                                                      3. Szefler SJ et al: Asthma across the ages: knowledge gaps in childhood asthma. J Allergy Clin Immunol. 133(1):3-13; quiz 14, 2014
                                                                                      4. Cadman RV et al: Pulmonary 3He magnetic resonance imaging of childhood asthma. J Allergy Clin Immunol. 131(2):369-76.e1-5, 2013
                                                                                      5. Ober C et al: The genetics of asthma and allergic disease: a 21st century perspective. Immunol Rev. 242(1):10-30, 2011
                                                                                      6. Szefler SJ: Advances in pediatric asthma in 2010: addressing the major issues. J Allergy Clin Immunol. 127(1):102-15, 2011
                                                                                      7. Bisgaard H et al: Long-term studies of the natural history of asthma in childhood. J Allergy Clin Immunol. 126(2):187-97; quiz 198-9, 2010
                                                                                      8. Bush A et al: Management of severe asthma in children. Lancet. 376(9743):814-25, 2010
                                                                                      9. Castro-Rodriguez JA: The Asthma Predictive Index: a very useful tool for predicting asthma in young children. J Allergy Clin Immunol. 126(2):212-6, 2010
                                                                                      10. de Groot EP et al: Comorbidities of asthma during childhood: possibly important, yet poorly studied. Eur Respir J. 36(3):671-8, 2010
                                                                                      11. Quizon A et al: Special considerations in pediatric asthma. Curr Opin Pharmacol. 10(3):272-5, 2010