link
Bookmarks
Asthma
Hank Baskin, MD
To access 4,300 diagnoses written by the world's leading experts in radiology.Try it free - 15 days
0
3
5
3

KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Pathology

          • Clinical Issues

            • Diagnostic Checklist

              TERMINOLOGY

              • Synonyms

                • Airway hyperreactivity
                • Reactive airways disease
              • Definitions

                • Chronic disease characterized by bronchial hyperresponsiveness, reversible airway obstruction, & chronic airway inflammation
                • Umbrella term for numerous phenotypes in which normally harmless environmental allergens lead to pathologic immune-mediated host response (i.e., not single disease)
                • Airway hyperresponsiveness → contraction of bronchial wall smooth muscle & cascade of inflammation → acute, reversible airway narrowing & airflow obstruction
                • United airway disease (UAD): Concept that upper & lower airways function immunologically as single organ
                  • Overwhelming majority of asthmatics have rhinitis; less commonly, nasal polyps & other sinonasal disorders

              IMAGING

              • General Features

                • Radiographic Findings

                  • CT Findings

                    • MR Findings

                      • Imaging Recommendations

                        DIFFERENTIAL DIAGNOSIS

                          PATHOLOGY

                          • General Features

                            • Gross Pathologic & Surgical Features

                              • Microscopic Features

                                CLINICAL ISSUES

                                • Presentation

                                  • Demographics

                                    • Natural History & Prognosis

                                      • Treatment

                                        DIAGNOSTIC CHECKLIST

                                        • Consider

                                          • Image Interpretation Pearls

                                            Selected References

                                            1. Silva TKBD et al: High-resolution CT pulmonary findings in children with severe asthma. J Pediatr (Rio J). 97(1):37-43, 2020
                                            2. Dharmage SC et al: Epidemiology of asthma in children and adults. Front Pediatr. 7:246, 2019
                                            3. Wu J et al: Effects of particulate matter (PM) on childhood asthma exacerbation and control in Xiamen, China. BMC Pediatr. 19(1):194, 2019
                                            4. Keet CA et al: Long-Term coarse particulate matter exposure is associated with asthma among children in medicaid. Am J Respir Crit Care Med. 197(6):737-46, 2018
                                            5. Loewen K et al: Prenatal antibiotic exposure and childhood asthma: a population-based study. Eur Respir J. 52(1), 2018
                                            6. Yii ACA et al: Precision medicine in united airways disease: a "treatable traits" approach. Allergy. 73(10):1964-78, 2018
                                            7. Ash SY et al: The role of imaging in the assessment of severe asthma. Curr Opin Pulm Med. 23(1):97-102, 2017
                                            8. Trivedi A et al: Using imaging as a biomarker for asthma. J Allergy Clin Immunol. 139(1):1-10, 2017
                                            9. Wu P et al: Relative importance and additive effects of maternal and infant risk factors on childhood asthma. PLoS One. 11(3):e0151705, 2016
                                            10. Narayanan S et al: Relevance of chest radiography in pediatric inpatients with asthma. J Asthma. 51(7):751-5, 2014
                                            11. Szefler SJ et al: Asthma across the ages: knowledge gaps in childhood asthma. J Allergy Clin Immunol. 133(1):3-13; quiz 14, 2014
                                            Related Anatomy
                                            Loading...
                                            Related Differential Diagnoses
                                            Loading...
                                            References
                                            Tables

                                            Tables

                                            KEY FACTS

                                            • Terminology

                                              • Imaging

                                                • Top Differential Diagnoses

                                                  • Pathology

                                                    • Clinical Issues

                                                      • Diagnostic Checklist

                                                        TERMINOLOGY

                                                        • Synonyms

                                                          • Airway hyperreactivity
                                                          • Reactive airways disease
                                                        • Definitions

                                                          • Chronic disease characterized by bronchial hyperresponsiveness, reversible airway obstruction, & chronic airway inflammation
                                                          • Umbrella term for numerous phenotypes in which normally harmless environmental allergens lead to pathologic immune-mediated host response (i.e., not single disease)
                                                          • Airway hyperresponsiveness → contraction of bronchial wall smooth muscle & cascade of inflammation → acute, reversible airway narrowing & airflow obstruction
                                                          • United airway disease (UAD): Concept that upper & lower airways function immunologically as single organ
                                                            • Overwhelming majority of asthmatics have rhinitis; less commonly, nasal polyps & other sinonasal disorders

                                                        IMAGING

                                                        • General Features

                                                          • Radiographic Findings

                                                            • CT Findings

                                                              • MR Findings

                                                                • Imaging Recommendations

                                                                  DIFFERENTIAL DIAGNOSIS

                                                                    PATHOLOGY

                                                                    • General Features

                                                                      • Gross Pathologic & Surgical Features

                                                                        • Microscopic Features

                                                                          CLINICAL ISSUES

                                                                          • Presentation

                                                                            • Demographics

                                                                              • Natural History & Prognosis

                                                                                • Treatment

                                                                                  DIAGNOSTIC CHECKLIST

                                                                                  • Consider

                                                                                    • Image Interpretation Pearls

                                                                                      Selected References

                                                                                      1. Silva TKBD et al: High-resolution CT pulmonary findings in children with severe asthma. J Pediatr (Rio J). 97(1):37-43, 2020
                                                                                      2. Dharmage SC et al: Epidemiology of asthma in children and adults. Front Pediatr. 7:246, 2019
                                                                                      3. Wu J et al: Effects of particulate matter (PM) on childhood asthma exacerbation and control in Xiamen, China. BMC Pediatr. 19(1):194, 2019
                                                                                      4. Keet CA et al: Long-Term coarse particulate matter exposure is associated with asthma among children in medicaid. Am J Respir Crit Care Med. 197(6):737-46, 2018
                                                                                      5. Loewen K et al: Prenatal antibiotic exposure and childhood asthma: a population-based study. Eur Respir J. 52(1), 2018
                                                                                      6. Yii ACA et al: Precision medicine in united airways disease: a "treatable traits" approach. Allergy. 73(10):1964-78, 2018
                                                                                      7. Ash SY et al: The role of imaging in the assessment of severe asthma. Curr Opin Pulm Med. 23(1):97-102, 2017
                                                                                      8. Trivedi A et al: Using imaging as a biomarker for asthma. J Allergy Clin Immunol. 139(1):1-10, 2017
                                                                                      9. Wu P et al: Relative importance and additive effects of maternal and infant risk factors on childhood asthma. PLoS One. 11(3):e0151705, 2016
                                                                                      10. Narayanan S et al: Relevance of chest radiography in pediatric inpatients with asthma. J Asthma. 51(7):751-5, 2014
                                                                                      11. Szefler SJ et al: Asthma across the ages: knowledge gaps in childhood asthma. J Allergy Clin Immunol. 133(1):3-13; quiz 14, 2014