link
Bookmarks
Atypical and Malignant Meningioma
Anne G. Osborn, MD, FACR
To access 4,300 diagnoses written by the world's leading experts in radiology.Try it free - 15 days
0
10
1
0

KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Pathology

          • Clinical Issues

            • Diagnostic Checklist

              TERMINOLOGY

              • Abbreviations

                • Atypical meningioma (AM), malignant meningioma (MM)
              • Definitions

                • Typical (benign) meningioma
                  • WHO grade 1 (80%)
                  • Common meningioma (CM) includes most meningioma subtypes
                • AM
                  • WHO grade 2 (15-18%)
                  • Chordoid, clear cell meningiomas
                • Anaplastic MM
                  • WHO grade 3 (2-4%)
                  • Papillary, rhabdoid meningiomas

              IMAGING

              • General Features

                • CT Findings

                  • MR Findings

                    • Angiographic Findings

                      • Nuclear Medicine Findings

                        • Imaging Recommendations

                          DIFFERENTIAL DIAGNOSIS

                            PATHOLOGY

                            • General Features

                              • Staging, Grading, & Classification

                                • Gross Pathologic & Surgical Features

                                  • Microscopic Features

                                    CLINICAL ISSUES

                                    • Demographics

                                      • Natural History & Prognosis

                                        • Treatment

                                          DIAGNOSTIC CHECKLIST

                                          • Image Interpretation Pearls

                                            Selected References

                                            1. Maier AD et al: Clinical and histopathological predictors of outcome in malignant meningioma. Neurosurg Rev. 43(2):643-53, 2020
                                            2. Xiaoai K et al: Differentiating microcystic meningioma from atypical meningioma using diffusion-weighted imaging. Neuroradiology. 62(5):601-7, 2020
                                            3. Champeaux C et al: Malignant meningioma: An international multicentre retrospective study. Neurosurgery. 85(3):E461-9, 2019
                                            4. Coggins WS et al: A systematic review of ion radiotherapy in maintaining local control regarding atypical and anaplastic meningiomas. World Neurosurg. 132:282-91, 2019
                                            5. Bi WL et al: High-grade meningiomas: biology and implications. Neurosurg Focus. 44(4):E2, 2018
                                            6. Collord G et al: An integrated genomic analysis of anaplastic meningioma identifies prognostic molecular signatures. Sci Rep. 8(1):13537, 2018
                                            7. Peyre M et al: De novo and secondary anaplastic meningiomas: a study of clinical and histomolecular prognostic factors. Neuro Oncol. 20(8):1113-21, 2018
                                            8. Kessler RA et al: Metastatic atypical and anaplastic meningioma: A case series and review of the literature. World Neurosurg. 101:47-56, 2017
                                            Related Anatomy
                                            Loading...
                                            Related Differential Diagnoses
                                            Loading...
                                            References
                                            Tables

                                            Tables

                                            KEY FACTS

                                            • Terminology

                                              • Imaging

                                                • Top Differential Diagnoses

                                                  • Pathology

                                                    • Clinical Issues

                                                      • Diagnostic Checklist

                                                        TERMINOLOGY

                                                        • Abbreviations

                                                          • Atypical meningioma (AM), malignant meningioma (MM)
                                                        • Definitions

                                                          • Typical (benign) meningioma
                                                            • WHO grade 1 (80%)
                                                            • Common meningioma (CM) includes most meningioma subtypes
                                                          • AM
                                                            • WHO grade 2 (15-18%)
                                                            • Chordoid, clear cell meningiomas
                                                          • Anaplastic MM
                                                            • WHO grade 3 (2-4%)
                                                            • Papillary, rhabdoid meningiomas

                                                        IMAGING

                                                        • General Features

                                                          • CT Findings

                                                            • MR Findings

                                                              • Angiographic Findings

                                                                • Nuclear Medicine Findings

                                                                  • Imaging Recommendations

                                                                    DIFFERENTIAL DIAGNOSIS

                                                                      PATHOLOGY

                                                                      • General Features

                                                                        • Staging, Grading, & Classification

                                                                          • Gross Pathologic & Surgical Features

                                                                            • Microscopic Features

                                                                              CLINICAL ISSUES

                                                                              • Demographics

                                                                                • Natural History & Prognosis

                                                                                  • Treatment

                                                                                    DIAGNOSTIC CHECKLIST

                                                                                    • Image Interpretation Pearls

                                                                                      Selected References

                                                                                      1. Maier AD et al: Clinical and histopathological predictors of outcome in malignant meningioma. Neurosurg Rev. 43(2):643-53, 2020
                                                                                      2. Xiaoai K et al: Differentiating microcystic meningioma from atypical meningioma using diffusion-weighted imaging. Neuroradiology. 62(5):601-7, 2020
                                                                                      3. Champeaux C et al: Malignant meningioma: An international multicentre retrospective study. Neurosurgery. 85(3):E461-9, 2019
                                                                                      4. Coggins WS et al: A systematic review of ion radiotherapy in maintaining local control regarding atypical and anaplastic meningiomas. World Neurosurg. 132:282-91, 2019
                                                                                      5. Bi WL et al: High-grade meningiomas: biology and implications. Neurosurg Focus. 44(4):E2, 2018
                                                                                      6. Collord G et al: An integrated genomic analysis of anaplastic meningioma identifies prognostic molecular signatures. Sci Rep. 8(1):13537, 2018
                                                                                      7. Peyre M et al: De novo and secondary anaplastic meningiomas: a study of clinical and histomolecular prognostic factors. Neuro Oncol. 20(8):1113-21, 2018
                                                                                      8. Kessler RA et al: Metastatic atypical and anaplastic meningioma: A case series and review of the literature. World Neurosurg. 101:47-56, 2017