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Atypical Choroid Plexus Papilloma
Chang Yueh Ho, MD
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Pathology

          • Clinical Issues

            TERMINOLOGY

            • Abbreviations

              • Atypical choroid plexus papilloma (aCPP)
            • Definitions

              • Choroid plexus papilloma (CPP) with increased mitotic activity and higher likelihood of recurrence (WHO grade II)
              • CPP with ≥ 2 mitoses per 10 high-power fields

            IMAGING

            • General Features

              • Imaging Recommendations

                • CT Findings

                  • MR Findings

                    DIFFERENTIAL DIAGNOSIS

                      PATHOLOGY

                      • General Features

                        • Staging, Grading, & Classification

                          • Gross Pathologic & Surgical Features

                            • Microscopic Features

                              CLINICAL ISSUES

                              • Presentation

                                • Demographics

                                  • Natural History & Prognosis

                                    DIAGNOSTIC CHECKLIST

                                    • Consider

                                      Selected References

                                      1. Jeibmann A et al: Malignant progression in choroid plexus papillomas. J Neurosurg. 107(3 Suppl):199-202, 2007
                                      2. Louis DN et al: The 2007 WHO classification of tumours of the central nervous system. Acta Neuropathol. 2007 Aug;114(2):97-109. Epub 2007 Jul 6. Review. Erratum in: Acta Neuropathol. 114(5):547, 2007
                                      3. Hasselblatt M et al: Identification of novel diagnostic markers for choroid plexus tumors: a microarray-based approach. Am J Surg Pathol. 30(1):66-74, 2006
                                      4. Jeibmann A et al: Prognostic implications of atypical histologic features in choroid plexus papilloma. J Neuropathol Exp Neurol. 65(11):1069-73, 2006
                                      5. Judkins AR et al: INI1 protein expression distinguishes atypical teratoid/rhabdoid tumor from choroid plexus carcinoma. J Neuropathol Exp Neurol. 64(5):391-7, 2005
                                      Related Anatomy
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                                      Related Differential Diagnoses
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                                      References
                                      Tables

                                      Tables

                                      KEY FACTS

                                      • Terminology

                                        • Imaging

                                          • Top Differential Diagnoses

                                            • Pathology

                                              • Clinical Issues

                                                TERMINOLOGY

                                                • Abbreviations

                                                  • Atypical choroid plexus papilloma (aCPP)
                                                • Definitions

                                                  • Choroid plexus papilloma (CPP) with increased mitotic activity and higher likelihood of recurrence (WHO grade II)
                                                  • CPP with ≥ 2 mitoses per 10 high-power fields

                                                IMAGING

                                                • General Features

                                                  • Imaging Recommendations

                                                    • CT Findings

                                                      • MR Findings

                                                        DIFFERENTIAL DIAGNOSIS

                                                          PATHOLOGY

                                                          • General Features

                                                            • Staging, Grading, & Classification

                                                              • Gross Pathologic & Surgical Features

                                                                • Microscopic Features

                                                                  CLINICAL ISSUES

                                                                  • Presentation

                                                                    • Demographics

                                                                      • Natural History & Prognosis

                                                                        DIAGNOSTIC CHECKLIST

                                                                        • Consider

                                                                          Selected References

                                                                          1. Jeibmann A et al: Malignant progression in choroid plexus papillomas. J Neurosurg. 107(3 Suppl):199-202, 2007
                                                                          2. Louis DN et al: The 2007 WHO classification of tumours of the central nervous system. Acta Neuropathol. 2007 Aug;114(2):97-109. Epub 2007 Jul 6. Review. Erratum in: Acta Neuropathol. 114(5):547, 2007
                                                                          3. Hasselblatt M et al: Identification of novel diagnostic markers for choroid plexus tumors: a microarray-based approach. Am J Surg Pathol. 30(1):66-74, 2006
                                                                          4. Jeibmann A et al: Prognostic implications of atypical histologic features in choroid plexus papilloma. J Neuropathol Exp Neurol. 65(11):1069-73, 2006
                                                                          5. Judkins AR et al: INI1 protein expression distinguishes atypical teratoid/rhabdoid tumor from choroid plexus carcinoma. J Neuropathol Exp Neurol. 64(5):391-7, 2005