Uncommon, chronic hepatitis of unknown etiology characterized by hyperglobulinemia, circulating autoantibodies, and inflammatory changes on hepatic histology
IMAGING
General Features
Radiographic Findings
CT Findings
MR Findings
Ultrasonographic Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
Staging, Grading, & Classification
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Selected References
Gomes NBN et al: Autoimmune hepatitis in practice, from diagnosis to complications: what is the role of imaging? A clinicoradiological review. Clin Imaging. 74:31-40, 2021
Mieli-Vergani G et al: Autoimmune hepatitis. Nat Rev Dis Primers. 4:18017, 2018
Malik N et al: Imaging of autoimmune hepatitis and overlap syndromes. Abdom Radiol (NY). 42(1):19-27, 2017
Weidner J et al: Marked improvement of the autoimmune syndrome associated with autoimmune hepatitis by treatment with sympathomimetic amines. Clin Exp Obstet Gynecol. 41(4):460-1, 2014
Culver EL et al: Systematic review: management options for primary sclerosing cholangitis and its variant forms - IgG4-associated cholangitis and overlap with autoimmune hepatitis. Aliment Pharmacol Ther. 33(12):1273-91, 2011
Czaja AJ: Cryptogenic chronic hepatitis and its changing guise in adults. Dig Dis Sci. 56(12):3421-38, 2011
Jothimani D et al: Treatment of autoimmune hepatitis: a review of current and evolving therapies. J Gastroenterol Hepatol. 26(4):619-27, 2011
Lohse AW et al: Autoimmune hepatitis. J Hepatol. 55(1):171-82, 2011
Mayo MJ: Management of autoimmune hepatitis. Curr Opin Gastroenterol. 27(3):224-30, 2011
Mieli-Vergani G et al: Autoimmune hepatitis. Nat Rev Gastroenterol Hepatol. 8(6):320-9, 2011
Potts JR et al: Optimizing management in autoimmune hepatitis with liver failure at initial presentation. World J Gastroenterol. 17(16):2070-5, 2011
Vergani D et al: Pharmacological management of autoimmune hepatitis. Expert Opin Pharmacother. 12(4):607-13, 2011
Sahni VA et al: Autoimmune hepatitis: CT and MR imaging features with histopathological correlation. Abdom Imaging. 35(1):75-84, 2010
Strassburg CP: Autoimmune hepatitis. Best Pract Res Clin Gastroenterol. 24(5):667-82, 2010
Bilaj F et al: MR imaging findings in autoimmune hepatitis: correlation with clinical staging. Radiology. 236(3):896-902, 2005
Related Anatomy
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Related Differential Diagnoses
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References
Tables
Tables
KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Clinical Issues
Diagnostic Checklist
TERMINOLOGY
Abbreviations
Autoimmune hepatitis (AIH)
Synonyms
Chronic active hepatitis
Definitions
Uncommon, chronic hepatitis of unknown etiology characterized by hyperglobulinemia, circulating autoantibodies, and inflammatory changes on hepatic histology
IMAGING
General Features
Radiographic Findings
CT Findings
MR Findings
Ultrasonographic Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
Staging, Grading, & Classification
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Selected References
Gomes NBN et al: Autoimmune hepatitis in practice, from diagnosis to complications: what is the role of imaging? A clinicoradiological review. Clin Imaging. 74:31-40, 2021
Mieli-Vergani G et al: Autoimmune hepatitis. Nat Rev Dis Primers. 4:18017, 2018
Malik N et al: Imaging of autoimmune hepatitis and overlap syndromes. Abdom Radiol (NY). 42(1):19-27, 2017
Weidner J et al: Marked improvement of the autoimmune syndrome associated with autoimmune hepatitis by treatment with sympathomimetic amines. Clin Exp Obstet Gynecol. 41(4):460-1, 2014
Culver EL et al: Systematic review: management options for primary sclerosing cholangitis and its variant forms - IgG4-associated cholangitis and overlap with autoimmune hepatitis. Aliment Pharmacol Ther. 33(12):1273-91, 2011
Czaja AJ: Cryptogenic chronic hepatitis and its changing guise in adults. Dig Dis Sci. 56(12):3421-38, 2011
Jothimani D et al: Treatment of autoimmune hepatitis: a review of current and evolving therapies. J Gastroenterol Hepatol. 26(4):619-27, 2011
Lohse AW et al: Autoimmune hepatitis. J Hepatol. 55(1):171-82, 2011
Mayo MJ: Management of autoimmune hepatitis. Curr Opin Gastroenterol. 27(3):224-30, 2011
Mieli-Vergani G et al: Autoimmune hepatitis. Nat Rev Gastroenterol Hepatol. 8(6):320-9, 2011
Potts JR et al: Optimizing management in autoimmune hepatitis with liver failure at initial presentation. World J Gastroenterol. 17(16):2070-5, 2011
Vergani D et al: Pharmacological management of autoimmune hepatitis. Expert Opin Pharmacother. 12(4):607-13, 2011
Sahni VA et al: Autoimmune hepatitis: CT and MR imaging features with histopathological correlation. Abdom Imaging. 35(1):75-84, 2010
Strassburg CP: Autoimmune hepatitis. Best Pract Res Clin Gastroenterol. 24(5):667-82, 2010
Bilaj F et al: MR imaging findings in autoimmune hepatitis: correlation with clinical staging. Radiology. 236(3):896-902, 2005
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