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Autoimmune Hepatitis
Michael P. Federle, MD, FACR
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Clinical Issues

          • Diagnostic Checklist

            TERMINOLOGY

            • Abbreviations

              • Autoimmune hepatitis (AIH)
            • Synonyms

              • Chronic active hepatitis
            • Definitions

              • Chronic hepatitis of unknown etiology characterized by hyperglobulinemia, circulating autoantibodies, and inflammatory changes on hepatic histology

            IMAGING

            • General Features

              • Radiographic Findings

                • CT Findings

                  • MR Findings

                    • Imaging Recommendations

                      DIFFERENTIAL DIAGNOSIS

                        PATHOLOGY

                        • Staging, Grading, & Classification

                          • Gross Pathologic & Surgical Features

                            • Microscopic Features

                              CLINICAL ISSUES

                              • Presentation

                                • Demographics

                                  • Natural History & Prognosis

                                    • Treatment

                                      DIAGNOSTIC CHECKLIST

                                      • Consider

                                        Selected References

                                        1. Weidner J et al: Marked improvement of the autoimmune syndrome associated with autoimmune hepatitis by treatment with sympathomimetic amines. Clin Exp Obstet Gynecol. 41(4):460-1, 2014
                                        2. Culver EL et al: Systematic review: management options for primary sclerosing cholangitis and its variant forms - IgG4-associated cholangitis and overlap with autoimmune hepatitis. Aliment Pharmacol Ther. 33(12):1273-91, 2011
                                        3. Czaja AJ: Cryptogenic chronic hepatitis and its changing guise in adults. Dig Dis Sci. 56(12):3421-38, 2011
                                        4. Jothimani D et al: Treatment of autoimmune hepatitis: a review of current and evolving therapies. J Gastroenterol Hepatol. 26(4):619-27, 2011
                                        5. Lohse AW et al: Autoimmune hepatitis. J Hepatol. 55(1):171-82, 2011
                                        6. Mayo MJ: Management of autoimmune hepatitis. Curr Opin Gastroenterol. 27(3):224-30, 2011
                                        7. Mieli-Vergani G et al: Autoimmune hepatitis. Nat Rev Gastroenterol Hepatol. 8(6):320-9, 2011
                                        8. Potts JR et al: Optimizing management in autoimmune hepatitis with liver failure at initial presentation. World J Gastroenterol. 17(16):2070-5, 2011
                                        9. Vergani D et al: Pharmacological management of autoimmune hepatitis. Expert Opin Pharmacother. 12(4):607-13, 2011
                                        10. Sahni VA et al: Autoimmune hepatitis: CT and MR imaging features with histopathological correlation. Abdom Imaging. 35(1):75-84, 2010
                                        11. Strassburg CP: Autoimmune hepatitis. Best Pract Res Clin Gastroenterol. 24(5):667-82, 2010
                                        12. Bilaj F et al: MR imaging findings in autoimmune hepatitis: correlation with clinical staging. Radiology. 236(3):896-902, 2005
                                        Related Anatomy
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                                        Related Differential Diagnoses
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                                        References
                                        Tables

                                        Tables

                                        KEY FACTS

                                        • Terminology

                                          • Imaging

                                            • Top Differential Diagnoses

                                              • Clinical Issues

                                                • Diagnostic Checklist

                                                  TERMINOLOGY

                                                  • Abbreviations

                                                    • Autoimmune hepatitis (AIH)
                                                  • Synonyms

                                                    • Chronic active hepatitis
                                                  • Definitions

                                                    • Chronic hepatitis of unknown etiology characterized by hyperglobulinemia, circulating autoantibodies, and inflammatory changes on hepatic histology

                                                  IMAGING

                                                  • General Features

                                                    • Radiographic Findings

                                                      • CT Findings

                                                        • MR Findings

                                                          • Imaging Recommendations

                                                            DIFFERENTIAL DIAGNOSIS

                                                              PATHOLOGY

                                                              • Staging, Grading, & Classification

                                                                • Gross Pathologic & Surgical Features

                                                                  • Microscopic Features

                                                                    CLINICAL ISSUES

                                                                    • Presentation

                                                                      • Demographics

                                                                        • Natural History & Prognosis

                                                                          • Treatment

                                                                            DIAGNOSTIC CHECKLIST

                                                                            • Consider

                                                                              Selected References

                                                                              1. Weidner J et al: Marked improvement of the autoimmune syndrome associated with autoimmune hepatitis by treatment with sympathomimetic amines. Clin Exp Obstet Gynecol. 41(4):460-1, 2014
                                                                              2. Culver EL et al: Systematic review: management options for primary sclerosing cholangitis and its variant forms - IgG4-associated cholangitis and overlap with autoimmune hepatitis. Aliment Pharmacol Ther. 33(12):1273-91, 2011
                                                                              3. Czaja AJ: Cryptogenic chronic hepatitis and its changing guise in adults. Dig Dis Sci. 56(12):3421-38, 2011
                                                                              4. Jothimani D et al: Treatment of autoimmune hepatitis: a review of current and evolving therapies. J Gastroenterol Hepatol. 26(4):619-27, 2011
                                                                              5. Lohse AW et al: Autoimmune hepatitis. J Hepatol. 55(1):171-82, 2011
                                                                              6. Mayo MJ: Management of autoimmune hepatitis. Curr Opin Gastroenterol. 27(3):224-30, 2011
                                                                              7. Mieli-Vergani G et al: Autoimmune hepatitis. Nat Rev Gastroenterol Hepatol. 8(6):320-9, 2011
                                                                              8. Potts JR et al: Optimizing management in autoimmune hepatitis with liver failure at initial presentation. World J Gastroenterol. 17(16):2070-5, 2011
                                                                              9. Vergani D et al: Pharmacological management of autoimmune hepatitis. Expert Opin Pharmacother. 12(4):607-13, 2011
                                                                              10. Sahni VA et al: Autoimmune hepatitis: CT and MR imaging features with histopathological correlation. Abdom Imaging. 35(1):75-84, 2010
                                                                              11. Strassburg CP: Autoimmune hepatitis. Best Pract Res Clin Gastroenterol. 24(5):667-82, 2010
                                                                              12. Bilaj F et al: MR imaging findings in autoimmune hepatitis: correlation with clinical staging. Radiology. 236(3):896-902, 2005