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Autosomal Dominant Polycystic Kidney Disease
Barton F. Lane, MD
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Clinical Issues

          • Diagnostic Checklist

            TERMINOLOGY

            • Abbreviations

              • Autosomal dominant polycystic kidney disease (ADPKD)
            • Synonyms

              • Potter classification type 3: Adult onset polycystic kidney disease
            • Definitions

              • Most common hereditary renal cystic disease
              • Progressive development of multiple enlarging, bilateral renal cysts, parenchymal replacement, and end-stage renal disease

            IMAGING

            • General Features

              • Ultrasonographic Findings

                • Radiographic Findings

                  • CT Findings

                    • MR Findings

                      • Imaging Recommendations

                        DIFFERENTIAL DIAGNOSIS

                          PATHOLOGY

                          • General Features

                            • Staging, Grading, & Classification

                              • Gross Pathologic & Surgical Features

                                CLINICAL ISSUES

                                • Presentation

                                  • Demographics

                                    • Natural History & Prognosis

                                      • Treatment

                                        DIAGNOSTIC CHECKLIST

                                        • Consider

                                          • Image Interpretation Pearls

                                            Selected References

                                            1. Nobakht N et al: Advances in autosomal dominant polycystic kidney disease: a clinical review. Kidney Med. 2(2):196-208, 2020
                                            2. Gimpel C et al: Imaging of kidney cysts and cystic kidney diseases in children: an International Working Group consensus statement. Radiology. 290(3):769-82, 2019
                                            3. Dillman JR et al: Hereditary renal cystic disorders: imaging of the kidneys and beyond. Radiographics. 37(3):924-46, 2017
                                            4. Akoh JA: Current management of autosomal dominant polycystic kidney disease. World J Nephrol. 4(4):468-79, 2015
                                            5. Avni FE et al: Imaging and classification of congenital cystic renal diseases. AJR Am J Roentgenol. 198(5):1004-13, 2012
                                            6. Katabathina VS et al: Adult renal cystic disease: a genetic, biological, and developmental primer. Radiographics. 30(6):1509-23, 2010
                                            7. Pei Y et al: Diagnosis and screening of autosomal dominant polycystic kidney disease. Adv Chronic Kidney Dis. 17(2):140-52, 2010
                                            Related Anatomy
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                                            Related Differential Diagnoses
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                                            References
                                            Tables

                                            Tables

                                            KEY FACTS

                                            • Terminology

                                              • Imaging

                                                • Top Differential Diagnoses

                                                  • Clinical Issues

                                                    • Diagnostic Checklist

                                                      TERMINOLOGY

                                                      • Abbreviations

                                                        • Autosomal dominant polycystic kidney disease (ADPKD)
                                                      • Synonyms

                                                        • Potter classification type 3: Adult onset polycystic kidney disease
                                                      • Definitions

                                                        • Most common hereditary renal cystic disease
                                                        • Progressive development of multiple enlarging, bilateral renal cysts, parenchymal replacement, and end-stage renal disease

                                                      IMAGING

                                                      • General Features

                                                        • Ultrasonographic Findings

                                                          • Radiographic Findings

                                                            • CT Findings

                                                              • MR Findings

                                                                • Imaging Recommendations

                                                                  DIFFERENTIAL DIAGNOSIS

                                                                    PATHOLOGY

                                                                    • General Features

                                                                      • Staging, Grading, & Classification

                                                                        • Gross Pathologic & Surgical Features

                                                                          CLINICAL ISSUES

                                                                          • Presentation

                                                                            • Demographics

                                                                              • Natural History & Prognosis

                                                                                • Treatment

                                                                                  DIAGNOSTIC CHECKLIST

                                                                                  • Consider

                                                                                    • Image Interpretation Pearls

                                                                                      Selected References

                                                                                      1. Nobakht N et al: Advances in autosomal dominant polycystic kidney disease: a clinical review. Kidney Med. 2(2):196-208, 2020
                                                                                      2. Gimpel C et al: Imaging of kidney cysts and cystic kidney diseases in children: an International Working Group consensus statement. Radiology. 290(3):769-82, 2019
                                                                                      3. Dillman JR et al: Hereditary renal cystic disorders: imaging of the kidneys and beyond. Radiographics. 37(3):924-46, 2017
                                                                                      4. Akoh JA: Current management of autosomal dominant polycystic kidney disease. World J Nephrol. 4(4):468-79, 2015
                                                                                      5. Avni FE et al: Imaging and classification of congenital cystic renal diseases. AJR Am J Roentgenol. 198(5):1004-13, 2012
                                                                                      6. Katabathina VS et al: Adult renal cystic disease: a genetic, biological, and developmental primer. Radiographics. 30(6):1509-23, 2010
                                                                                      7. Pei Y et al: Diagnosis and screening of autosomal dominant polycystic kidney disease. Adv Chronic Kidney Dis. 17(2):140-52, 2010