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Avascular Necrosis
Fathima Fijula P. Manzil, MD; Umesh D. Oza, MD
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Clinical Issues

          • Diagnostic Checklist

            TERMINOLOGY

            • Definitions

              • Avascular necrosis (AVN): Ischemic death of trabecular bone and marrow
                • a.k.a. aseptic necrosis, bone infarct, osteonecrosis, osseous necrosis, ischemic necrosis

            IMAGING

            • General Features

              • Nuclear Medicine Findings

                • Radiographic Findings

                  • CT Findings

                    • MR Findings

                      • Imaging Recommendations

                        DIFFERENTIAL DIAGNOSIS

                          PATHOLOGY

                          • General Features

                            • Gross Pathologic & Surgical Features

                              • Microscopic Features

                                CLINICAL ISSUES

                                • Presentation

                                  • Demographics

                                    • Natural History & Prognosis

                                      • Treatment

                                        DIAGNOSTIC CHECKLIST

                                        • Consider

                                          Selected References

                                          1. An YS et al: Clinical characteristics and role of whole-body bone scan in multifocal osteonecrosis. BMC Musculoskelet Disord. 20(1):23, 2019
                                          2. Agrawal K et al: Nuclear medicine imaging in osteonecrosis of hip: Old and current concepts. World J Orthop. 8(10):747-53, 2017
                                          3. Joshi JK et al: Role of nuclear medicine imaging in recognizing different causes of osteonecrosis of the jaw. Clin Nucl Med. 38(1):40-3, 2013
                                          4. Buchan CA et al: Imaging of postoperative avascular necrosis of the ankle and foot. Semin Musculoskelet Radiol. 16(3):192-204, 2012
                                          5. Lee GC et al: Are we evaluating osteonecrosis adequately? Int Orthop. 36(12):2433-9, 2012
                                          6. Sohn MH et al: F-18 FDG uptake in osteonecrosis mimicking bone metastasis on PET/CT images. Clin Nucl Med. 32(6):496-7, 2007
                                          Related Anatomy
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                                          Related Differential Diagnoses
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                                          References
                                          Tables

                                          Tables

                                          KEY FACTS

                                          • Terminology

                                            • Imaging

                                              • Top Differential Diagnoses

                                                • Clinical Issues

                                                  • Diagnostic Checklist

                                                    TERMINOLOGY

                                                    • Definitions

                                                      • Avascular necrosis (AVN): Ischemic death of trabecular bone and marrow
                                                        • a.k.a. aseptic necrosis, bone infarct, osteonecrosis, osseous necrosis, ischemic necrosis

                                                    IMAGING

                                                    • General Features

                                                      • Nuclear Medicine Findings

                                                        • Radiographic Findings

                                                          • CT Findings

                                                            • MR Findings

                                                              • Imaging Recommendations

                                                                DIFFERENTIAL DIAGNOSIS

                                                                  PATHOLOGY

                                                                  • General Features

                                                                    • Gross Pathologic & Surgical Features

                                                                      • Microscopic Features

                                                                        CLINICAL ISSUES

                                                                        • Presentation

                                                                          • Demographics

                                                                            • Natural History & Prognosis

                                                                              • Treatment

                                                                                DIAGNOSTIC CHECKLIST

                                                                                • Consider

                                                                                  Selected References

                                                                                  1. An YS et al: Clinical characteristics and role of whole-body bone scan in multifocal osteonecrosis. BMC Musculoskelet Disord. 20(1):23, 2019
                                                                                  2. Agrawal K et al: Nuclear medicine imaging in osteonecrosis of hip: Old and current concepts. World J Orthop. 8(10):747-53, 2017
                                                                                  3. Joshi JK et al: Role of nuclear medicine imaging in recognizing different causes of osteonecrosis of the jaw. Clin Nucl Med. 38(1):40-3, 2013
                                                                                  4. Buchan CA et al: Imaging of postoperative avascular necrosis of the ankle and foot. Semin Musculoskelet Radiol. 16(3):192-204, 2012
                                                                                  5. Lee GC et al: Are we evaluating osteonecrosis adequately? Int Orthop. 36(12):2433-9, 2012
                                                                                  6. Sohn MH et al: F-18 FDG uptake in osteonecrosis mimicking bone metastasis on PET/CT images. Clin Nucl Med. 32(6):496-7, 2007