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Axillary Nodal Calcification
Haydee Ojeda-Fournier, MD; Wei Tse Yang, MBBS
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Clinical Issues

          TERMINOLOGY

          • Definitions

            • Ca⁺⁺ or radiodense deposits, such as gold, iron, or other metals, within axillary lymph nodes

          IMAGING

          • General Features

            • Mammographic Findings

              • Ultrasonographic Findings

                • MR Findings

                  • Nuclear Medicine Findings

                    • Image-Guided Biopsy

                      • Imaging Recommendations

                        DIFFERENTIAL DIAGNOSIS

                          PATHOLOGY

                          • General Features

                            • Microscopic Features

                              CLINICAL ISSUES

                              • Treatment

                                Selected References

                                1. Johnson JM et al: Axillary lymph node calcification: a review of local and systemic disease processes. Contemp Diag Radiol. 37(13):1-6, 2014
                                2. Mentrikoski MJ et al: Tattoo ink within lymph nodes: a possible clinical mimicker of abnormal calcifications. Breast J. 20(3):314-5, 2014
                                3. Lee S et al: Kikuchi disease: differentiation from tuberculous lymphadenitis based on patterns of nodal necrosis on CT. AJNR Am J Neuroradiol. 33(1):135-40, 2012
                                4. Cao MM et al: Mammographic signs of systemic disease. Radiographics. 31(4):1085-100, 2011
                                5. Mukund A et al: CT patterns of nodal disease in pediatric chest tuberculosis. World J Radiol. 3(1):17-23, 2011
                                6. Burkill GJ et al: Significance of tumour calcification in ovarian carcinoma. Br J Radiol. 82(980):640-4, 2009
                                7. Bedi DG et al: Cortical morphologic features of axillary lymph nodes as a predictor of metastasis in breast cancer: in vitro sonographic study. AJR Am J Roentgenol. 191(3):646-52, 2008
                                8. Gormly K et al: Calcified nodal metastasis from squamous cell carcinoma of the head and neck. Australas Radiol. 48(2):240-2, 2004
                                9. Honegger MM et al: Tattoo pigment mimicking axillary lymph node calcifications on mammography. AJR Am J Roentgenol. 183(3):831-2, 2004
                                10. Groves AM et al: Mammographic axillary node calcification caused by metastatic breast carcinoma. Breast. 11(3):267-9, 2002
                                11. Singer C et al: Mammographic appearance of axillary lymph node calcification in patients with metastatic ovarian carcinoma. AJR Am J Roentgenol. 176(6):1437-40, 2001
                                12. Eisenkraft BL et al: The spectrum of benign and malignant etiologies of cervical node calcification. AJR Am J Roentgenol. 172(5):1433-7, 1999
                                13. Hooley R et al: Calcifications in axillary lymph nodes caused by fat necrosis. AJR Am J Roentgenol. 167(3):627-8, 1996
                                14. Bruwer A et al: Punctate intranodal gold deposits simulating microcalcifications on mammograms. Radiology. 163(1):87-8, 1987
                                Related Anatomy
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                                Related Differential Diagnoses
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                                References
                                Tables

                                Tables

                                KEY FACTS

                                • Terminology

                                  • Imaging

                                    • Top Differential Diagnoses

                                      • Clinical Issues

                                        TERMINOLOGY

                                        • Definitions

                                          • Ca⁺⁺ or radiodense deposits, such as gold, iron, or other metals, within axillary lymph nodes

                                        IMAGING

                                        • General Features

                                          • Mammographic Findings

                                            • Ultrasonographic Findings

                                              • MR Findings

                                                • Nuclear Medicine Findings

                                                  • Image-Guided Biopsy

                                                    • Imaging Recommendations

                                                      DIFFERENTIAL DIAGNOSIS

                                                        PATHOLOGY

                                                        • General Features

                                                          • Microscopic Features

                                                            CLINICAL ISSUES

                                                            • Treatment

                                                              Selected References

                                                              1. Johnson JM et al: Axillary lymph node calcification: a review of local and systemic disease processes. Contemp Diag Radiol. 37(13):1-6, 2014
                                                              2. Mentrikoski MJ et al: Tattoo ink within lymph nodes: a possible clinical mimicker of abnormal calcifications. Breast J. 20(3):314-5, 2014
                                                              3. Lee S et al: Kikuchi disease: differentiation from tuberculous lymphadenitis based on patterns of nodal necrosis on CT. AJNR Am J Neuroradiol. 33(1):135-40, 2012
                                                              4. Cao MM et al: Mammographic signs of systemic disease. Radiographics. 31(4):1085-100, 2011
                                                              5. Mukund A et al: CT patterns of nodal disease in pediatric chest tuberculosis. World J Radiol. 3(1):17-23, 2011
                                                              6. Burkill GJ et al: Significance of tumour calcification in ovarian carcinoma. Br J Radiol. 82(980):640-4, 2009
                                                              7. Bedi DG et al: Cortical morphologic features of axillary lymph nodes as a predictor of metastasis in breast cancer: in vitro sonographic study. AJR Am J Roentgenol. 191(3):646-52, 2008
                                                              8. Gormly K et al: Calcified nodal metastasis from squamous cell carcinoma of the head and neck. Australas Radiol. 48(2):240-2, 2004
                                                              9. Honegger MM et al: Tattoo pigment mimicking axillary lymph node calcifications on mammography. AJR Am J Roentgenol. 183(3):831-2, 2004
                                                              10. Groves AM et al: Mammographic axillary node calcification caused by metastatic breast carcinoma. Breast. 11(3):267-9, 2002
                                                              11. Singer C et al: Mammographic appearance of axillary lymph node calcification in patients with metastatic ovarian carcinoma. AJR Am J Roentgenol. 176(6):1437-40, 2001
                                                              12. Eisenkraft BL et al: The spectrum of benign and malignant etiologies of cervical node calcification. AJR Am J Roentgenol. 172(5):1433-7, 1999
                                                              13. Hooley R et al: Calcifications in axillary lymph nodes caused by fat necrosis. AJR Am J Roentgenol. 167(3):627-8, 1996
                                                              14. Bruwer A et al: Punctate intranodal gold deposits simulating microcalcifications on mammograms. Radiology. 163(1):87-8, 1987