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Benign Breast Conditions
Fathima Fijula P. Manzil, MD
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Clinical Issues

          • Diagnostic Checklist

            • Scanning Tips

              IMAGING

              • General Features

                • Nuclear Medicine Findings

                  DIFFERENTIAL DIAGNOSIS

                    CLINICAL ISSUES

                    • Presentation

                      DIAGNOSTIC CHECKLIST

                      • Image Interpretation Pearls

                        Selected References

                        1. Yu P et al: Correlation between 18F-FDG PET/CT findings and BI-RADS assessment using ultrasound in the evaluation of breast lesions: A Multicenter Study. Acad Radiol. ePub, 2019
                        2. Palot Manzil FF et al: 18F-FDG PET/CT unveiling of implant rupture and clinically unsuspected silicone granuloma in treated breast cancer. J Nucl Med Technol. 46(4):394-5, 2018
                        3. Tayyab SJ et al: A pictorial review: multimodality imaging of benign and suspicious features of fat necrosis in the breast. Br J Radiol. 20180213, 2018
                        4. Verma P et al: Increased F-FDG uptake in bilateral gynecomastia secondary to feminizing adrenal tumor: A rare case report and review of literature. Indian J Nucl Med. 32(2):145-7, 2017
                        5. Dong A et al: Spectrum of the breast lesions with increased 18F-FDG uptake on PET/CT. Clin Nucl Med. 41(7):543-57, 2016
                        6. Choi EK et al: Herpes zoster mimicking breast cancer with axillary lymph node metastasis on PET/CT. Clin Nucl Med. 40(7):572-3, 2015
                        7. Adejolu M et al: False-positive lesions mimicking breast cancer on FDG PET and PET/CT. AJR Am J Roentgenol. 198(3):W304-14, 2012
                        8. Lakhani P et al: Correlation between quantified breast densities from digital mammography and 18F-FDG PET uptake. Breast J. 15(4):339-47, 2009
                        9. Lim HS et al: FDG PET/CT for the detection and evaluation of breast diseases: usefulness and limitations. Radiographics. 27 Suppl 1:S197-213, 2007
                        10. Metser U et al: Benign nonphysiologic lesions with increased 18F-FDG uptake on PET/CT: characterization and incidence. AJR Am J Roentgenol. 189(5):1203-10, 2007
                        11. Berg WA et al: High-resolution fluorodeoxyglucose positron emission tomography with compression ("positron emission mammography") is highly accurate in depicting primary breast cancer. Breast J. 12(4):309-23, 2006
                        12. Kumar R et al: Clinicopathologic factors associated with false negative FDG-PET in primary breast cancer. Breast Cancer Res Treat. 98(3):267-74, 2006
                        13. Abouzied MM et al: 18F-FDG imaging: pitfalls and artifacts. J Nucl Med Technol. 33(3):145-55; quiz 162-3, 2005
                        14. Rosen EL et al: Detection of primary breast carcinoma with a dedicated, large-field-of-view FDG PET mammography device: initial experience. Radiology. 234(2):527-34, 2005
                        15. Hurwitz R: F-18 FDG positron emission tomographic imaging in a case of ruptured breast implant: inflammation or recurrent tumor? Clin Nucl Med. 28(9):755-6, 2003
                        16. Vranjesevic D et al: Relationship between 18F-FDG uptake and breast density in women with normal breast tissue. J Nucl Med. 44(8):1238-42, 2003
                        17. Avril N et al: Breast imaging with positron emission tomography and fluorine-18 fluorodeoxyglucose: use and limitations. J Clin Oncol. 18(20):3495-502, 2000
                        18. Bakheet SM et al: F-18 FDG uptake in breast infection and inflammation. Clin Nucl Med. 25(2):100-3, 2000
                        Related Anatomy
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                        Related Differential Diagnoses
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                        References
                        Tables

                        Tables

                        KEY FACTS

                        • Terminology

                          • Imaging

                            • Top Differential Diagnoses

                              • Clinical Issues

                                • Diagnostic Checklist

                                  • Scanning Tips

                                    IMAGING

                                    • General Features

                                      • Nuclear Medicine Findings

                                        DIFFERENTIAL DIAGNOSIS

                                          CLINICAL ISSUES

                                          • Presentation

                                            DIAGNOSTIC CHECKLIST

                                            • Image Interpretation Pearls

                                              Selected References

                                              1. Yu P et al: Correlation between 18F-FDG PET/CT findings and BI-RADS assessment using ultrasound in the evaluation of breast lesions: A Multicenter Study. Acad Radiol. ePub, 2019
                                              2. Palot Manzil FF et al: 18F-FDG PET/CT unveiling of implant rupture and clinically unsuspected silicone granuloma in treated breast cancer. J Nucl Med Technol. 46(4):394-5, 2018
                                              3. Tayyab SJ et al: A pictorial review: multimodality imaging of benign and suspicious features of fat necrosis in the breast. Br J Radiol. 20180213, 2018
                                              4. Verma P et al: Increased F-FDG uptake in bilateral gynecomastia secondary to feminizing adrenal tumor: A rare case report and review of literature. Indian J Nucl Med. 32(2):145-7, 2017
                                              5. Dong A et al: Spectrum of the breast lesions with increased 18F-FDG uptake on PET/CT. Clin Nucl Med. 41(7):543-57, 2016
                                              6. Choi EK et al: Herpes zoster mimicking breast cancer with axillary lymph node metastasis on PET/CT. Clin Nucl Med. 40(7):572-3, 2015
                                              7. Adejolu M et al: False-positive lesions mimicking breast cancer on FDG PET and PET/CT. AJR Am J Roentgenol. 198(3):W304-14, 2012
                                              8. Lakhani P et al: Correlation between quantified breast densities from digital mammography and 18F-FDG PET uptake. Breast J. 15(4):339-47, 2009
                                              9. Lim HS et al: FDG PET/CT for the detection and evaluation of breast diseases: usefulness and limitations. Radiographics. 27 Suppl 1:S197-213, 2007
                                              10. Metser U et al: Benign nonphysiologic lesions with increased 18F-FDG uptake on PET/CT: characterization and incidence. AJR Am J Roentgenol. 189(5):1203-10, 2007
                                              11. Berg WA et al: High-resolution fluorodeoxyglucose positron emission tomography with compression ("positron emission mammography") is highly accurate in depicting primary breast cancer. Breast J. 12(4):309-23, 2006
                                              12. Kumar R et al: Clinicopathologic factors associated with false negative FDG-PET in primary breast cancer. Breast Cancer Res Treat. 98(3):267-74, 2006
                                              13. Abouzied MM et al: 18F-FDG imaging: pitfalls and artifacts. J Nucl Med Technol. 33(3):145-55; quiz 162-3, 2005
                                              14. Rosen EL et al: Detection of primary breast carcinoma with a dedicated, large-field-of-view FDG PET mammography device: initial experience. Radiology. 234(2):527-34, 2005
                                              15. Hurwitz R: F-18 FDG positron emission tomographic imaging in a case of ruptured breast implant: inflammation or recurrent tumor? Clin Nucl Med. 28(9):755-6, 2003
                                              16. Vranjesevic D et al: Relationship between 18F-FDG uptake and breast density in women with normal breast tissue. J Nucl Med. 44(8):1238-42, 2003
                                              17. Avril N et al: Breast imaging with positron emission tomography and fluorine-18 fluorodeoxyglucose: use and limitations. J Clin Oncol. 18(20):3495-502, 2000
                                              18. Bakheet SM et al: F-18 FDG uptake in breast infection and inflammation. Clin Nucl Med. 25(2):100-3, 2000