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Benign Causes of FDG Activity
Todd M. Blodgett, MD; Alexander Ryan, MD
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Pathology

          • Diagnostic Checklist

            TERMINOLOGY

            • Synonyms

              • Nonmalignant areas of increased metabolism
            • Definitions

              • Benign nonphysiologic uptake of FDG may be encountered in as many as 25% of studies
                • As many as 75% of those lesions will be inflammatory

            IMAGING

            • General Features

              • Nuclear Medicine Findings

                DIFFERENTIAL DIAGNOSIS

                  PATHOLOGY

                  • General Features

                    DIAGNOSTIC CHECKLIST

                    • Consider

                      Selected References

                      1. Chryssikos T et al: FDG-PET imaging can diagnose periprosthetic infection of the hip. Clin Orthop Relat Res. 466(6):1338-42, 2008
                      2. Chundru S et al: Granulomatous disease: is it a nuisance or an asset during PET/computed tomography evaluation of lung cancers? Nucl Med Commun. 29(7):623-7, 2008
                      3. Nigg AP et al: Tuberculous Spondylitis (Pott's Disease). Infection. 36(3):293-4, 2008
                      4. Saleem BR et al: Periaortic endograft infection due to Listeria monocytogenes treated with graft preservation. J Vasc Surg. 47(3):635-7, 2008
                      5. Balink H et al: Diagnosis of abdominal aortic prosthesis infection with FDG-PET/CT. Vasc Endovascular Surg. 41(5):428-32, 2007
                      6. Helleman JN et al: Mycotic aneurysm of the descending thoracic aorta. Review and case report. Acta Chir Belg. 107(5):544-7, 2007
                      7. Inoue K et al: Diagnosing active inflammation in the SAPHO syndrome using 18FDG-PET/CT in suspected metastatic vertebral bone tumors. Ann Nucl Med. 21(8):477-80, 2007
                      8. Kang K et al: Positron emission tomographic findings in a tuberculous brain abscess. Ann Nucl Med. 21(5):303-6, 2007
                      9. Maldonado F et al: Focal organizing pneumonia on surgical lung biopsy: causes, clinicoradiologic features, and outcomes. Chest. 132(5):1579-83, 2007
                      10. Sheehy N et al: Acute varicella infection mimics recurrent Hodgkin's disease on F-18 FDG PET/CT. Clin Nucl Med. 32(10):820-1, 2007
                      11. Lustberg MB et al: FDG PET/CT Findings in Acute Adult Mononucleosis Mimicking Malignant Lymphoma. Eur J Haematol. (In Press)
                      Related Anatomy
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                      Related Differential Diagnoses
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                      References
                      Tables

                      Tables

                      KEY FACTS

                      • Terminology

                        • Imaging

                          • Top Differential Diagnoses

                            • Pathology

                              • Diagnostic Checklist

                                TERMINOLOGY

                                • Synonyms

                                  • Nonmalignant areas of increased metabolism
                                • Definitions

                                  • Benign nonphysiologic uptake of FDG may be encountered in as many as 25% of studies
                                    • As many as 75% of those lesions will be inflammatory

                                IMAGING

                                • General Features

                                  • Nuclear Medicine Findings

                                    DIFFERENTIAL DIAGNOSIS

                                      PATHOLOGY

                                      • General Features

                                        DIAGNOSTIC CHECKLIST

                                        • Consider

                                          Selected References

                                          1. Chryssikos T et al: FDG-PET imaging can diagnose periprosthetic infection of the hip. Clin Orthop Relat Res. 466(6):1338-42, 2008
                                          2. Chundru S et al: Granulomatous disease: is it a nuisance or an asset during PET/computed tomography evaluation of lung cancers? Nucl Med Commun. 29(7):623-7, 2008
                                          3. Nigg AP et al: Tuberculous Spondylitis (Pott's Disease). Infection. 36(3):293-4, 2008
                                          4. Saleem BR et al: Periaortic endograft infection due to Listeria monocytogenes treated with graft preservation. J Vasc Surg. 47(3):635-7, 2008
                                          5. Balink H et al: Diagnosis of abdominal aortic prosthesis infection with FDG-PET/CT. Vasc Endovascular Surg. 41(5):428-32, 2007
                                          6. Helleman JN et al: Mycotic aneurysm of the descending thoracic aorta. Review and case report. Acta Chir Belg. 107(5):544-7, 2007
                                          7. Inoue K et al: Diagnosing active inflammation in the SAPHO syndrome using 18FDG-PET/CT in suspected metastatic vertebral bone tumors. Ann Nucl Med. 21(8):477-80, 2007
                                          8. Kang K et al: Positron emission tomographic findings in a tuberculous brain abscess. Ann Nucl Med. 21(5):303-6, 2007
                                          9. Maldonado F et al: Focal organizing pneumonia on surgical lung biopsy: causes, clinicoradiologic features, and outcomes. Chest. 132(5):1579-83, 2007
                                          10. Sheehy N et al: Acute varicella infection mimics recurrent Hodgkin's disease on F-18 FDG PET/CT. Clin Nucl Med. 32(10):820-1, 2007
                                          11. Lustberg MB et al: FDG PET/CT Findings in Acute Adult Mononucleosis Mimicking Malignant Lymphoma. Eur J Haematol. (In Press)