link
Bookmarks
Berylliosis
Sonia L. Betancourt Cuellar, MD
To access 4,300 diagnoses written by the world's leading experts in radiology, please log in or subscribe.Log inSubscribe
0
8
1
4

KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Pathology

          • Clinical Issues

            TERMINOLOGY

            • Abbreviations

              • Acute beryllium exposure (ABE)
              • Chronic beryllium disease (CBD)
              • Delayed-type hypersensitivity to beryllium (BES)
            • Synonyms

              • Salem sarcoidosis
                • Seen in young women in fluorescent light industry in Salem, Massachusetts in 1940s
            • Definitions

              • Beryllium: Gray, lightweight metal with high thermal stability and conductivity
                • Aerospace, telecommunication, defense, computer, medical, and nuclear industries
              • Inhalation of dust, aerosol, or fumes produces 2 types of lung injury
                • Acute chemical pneumonitis (uncommon)
                • Chronic granulomatous disease
              • Diagnosis requires
                • History of beryllium exposure
                • Positive beryllium-specific lymphocyte proliferation test (in blood or bronchoalveolar lavage fluid)
                • Nonnecrotizing granulomas on histology

            IMAGING

            • General Features

              • Radiographic Findings

                • CT Findings

                  • Imaging Recommendations

                    DIFFERENTIAL DIAGNOSIS

                      PATHOLOGY

                      • General Features

                        • Staging, Grading, & Classification

                          • Gross Pathologic & Surgical Features

                            CLINICAL ISSUES

                            • Presentation

                              • Demographics

                                • Natural History & Prognosis

                                  • Treatment

                                    DIAGNOSTIC CHECKLIST

                                    • Consider

                                      • Image Interpretation Pearls

                                        Selected References

                                        1. Mayer A et al: Beryllium and other metal-induced lung disease. Curr Opin Pulm Med. 21(2):178-84, 2015
                                        2. Mayer AS et al: Sarcoidosis and chronic beryllium disease: similarities and differences. Semin Respir Crit Care Med. 35(3):316-29, 2014
                                        3. Flors L et al: Uncommon occupational lung diseases: high-resolution CT findings. AJR Am J Roentgenol. 194(1):W20-6, 2010
                                        4. Sharma N et al: Chronic beryllium disease: computed tomographic findings. J Comput Assist Tomogr. 34(6):945-8, 2010
                                        Related Anatomy
                                        Loading...
                                        Related Differential Diagnoses
                                        Loading...
                                        References
                                        Tables

                                        Tables

                                        KEY FACTS

                                        • Terminology

                                          • Imaging

                                            • Top Differential Diagnoses

                                              • Pathology

                                                • Clinical Issues

                                                  TERMINOLOGY

                                                  • Abbreviations

                                                    • Acute beryllium exposure (ABE)
                                                    • Chronic beryllium disease (CBD)
                                                    • Delayed-type hypersensitivity to beryllium (BES)
                                                  • Synonyms

                                                    • Salem sarcoidosis
                                                      • Seen in young women in fluorescent light industry in Salem, Massachusetts in 1940s
                                                  • Definitions

                                                    • Beryllium: Gray, lightweight metal with high thermal stability and conductivity
                                                      • Aerospace, telecommunication, defense, computer, medical, and nuclear industries
                                                    • Inhalation of dust, aerosol, or fumes produces 2 types of lung injury
                                                      • Acute chemical pneumonitis (uncommon)
                                                      • Chronic granulomatous disease
                                                    • Diagnosis requires
                                                      • History of beryllium exposure
                                                      • Positive beryllium-specific lymphocyte proliferation test (in blood or bronchoalveolar lavage fluid)
                                                      • Nonnecrotizing granulomas on histology

                                                  IMAGING

                                                  • General Features

                                                    • Radiographic Findings

                                                      • CT Findings

                                                        • Imaging Recommendations

                                                          DIFFERENTIAL DIAGNOSIS

                                                            PATHOLOGY

                                                            • General Features

                                                              • Staging, Grading, & Classification

                                                                • Gross Pathologic & Surgical Features

                                                                  CLINICAL ISSUES

                                                                  • Presentation

                                                                    • Demographics

                                                                      • Natural History & Prognosis

                                                                        • Treatment

                                                                          DIAGNOSTIC CHECKLIST

                                                                          • Consider

                                                                            • Image Interpretation Pearls

                                                                              Selected References

                                                                              1. Mayer A et al: Beryllium and other metal-induced lung disease. Curr Opin Pulm Med. 21(2):178-84, 2015
                                                                              2. Mayer AS et al: Sarcoidosis and chronic beryllium disease: similarities and differences. Semin Respir Crit Care Med. 35(3):316-29, 2014
                                                                              3. Flors L et al: Uncommon occupational lung diseases: high-resolution CT findings. AJR Am J Roentgenol. 194(1):W20-6, 2010
                                                                              4. Sharma N et al: Chronic beryllium disease: computed tomographic findings. J Comput Assist Tomogr. 34(6):945-8, 2010