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KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Diagnostic Checklist
TERMINOLOGY
Synonyms
Bile duct microhamartoma
von Meyenburg complex
Definitions
Uncommon benign malformations of biliary tract
IMAGING
General Features
CT Findings
MR Findings
Ultrasonographic Findings
Angiographic Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Staging, Grading, & Classification
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Image Interpretation Pearls
Selected References
Taguchi T et al: "Starry sky" appearance from multiple biliary hamartomas. N Engl J Med. 382(16):e33, 2020
Torbenson MS: Hamartomas and malformations of the liver. Semin Diagn Pathol. 36(1):39-47, 2019
Giambelluca D et al: The starry sky liver: multiple biliary hamartomas on MR cholangiopancreatography. Abdom Radiol (NY). 43(9):2529-30, 2018
Lin S et al: A study of multiple biliary hamartomas based on 1697 liver biopsies. Eur J Gastroenterol Hepatol. 25(8):948-52, 2013
Gil-Bello D et al: Calcification in biliary hamartomatosis. Br J Radiol. 85(1012):e99-101, 2012
Desmet VJ: Ductal plates in hepatic ductular reactions. Hypothesis and implications. III. Implications for liver pathology. Virchows Arch. 458(3):271-9, 2011
Venkatanarasimha N et al: Imaging features of ductal plate malformations in adults. Clin Radiol. 66(11):1086-93, 2011
Drenth JP et al: Congenital fibrocystic liver diseases. Best Pract Res Clin Gastroenterol. 24(5):573-84, 2010
Hughes NR et al: An immunohistochemical profile of the so-called bile duct adenoma: clues to pathogenesis. Am J Surg Pathol. 34(9):1312-8, 2010
Tohmé-Noun C et al: Multiple biliary hamartomas: magnetic resonance features with histopathologic correlation. Eur Radiol. 18(3):493-9, 2008
Orii T et al: Cholangiocarcinoma arising from preexisting biliary hamartoma of liver--report of a case. Hepatogastroenterology. 50(50):333-6, 2003
Mortele B et al: Hepatic bile duct hamartomas (von Meyenburg complexes): MR and MR cholangiography findings. J Comput Assist Tomogr. 26(3):438-43, 2002
Allgaier HP et al: Ampullary hamartoma: a rare cause of biliary obstruction. Digestion. 60(5):497-500, 1999
Semelka RC et al: Biliary hamartomas: solitary and multiple lesions shown on current MR techniques including gadolinium enhancement. J Magn Reson Imaging. 10(2):196-201, 1999
von Schweinitz D et al: Mesenchymal hamartoma of the liver--new insight into histogenesis. J Pediatr Surg. 34(8):1269-71, 1999
Cheung YC et al: MRI of multiple biliary hamartomas. Br J Radiol. 70(833):527-9, 1997
Principe A et al: Bile duct hamartomas: diagnostic problems and treatment. Hepatogastroenterology. 44(16):994-7, 1997
Iha H et al: Biliary hamartomas simulating multiple hepatic metastasis on imaging findings. Kurume Med J. 43(3):231-5, 1996
Lev-Toaff AS et al: The radiologic and pathologic spectrum of biliary hamartomas. AJR Am J Roentgenol. 165(2):309-13, 1995
Related Anatomy
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Related Differential Diagnoses
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References
Tables
Tables
KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Diagnostic Checklist
TERMINOLOGY
Synonyms
Bile duct microhamartoma
von Meyenburg complex
Definitions
Uncommon benign malformations of biliary tract
IMAGING
General Features
CT Findings
MR Findings
Ultrasonographic Findings
Angiographic Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Staging, Grading, & Classification
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Image Interpretation Pearls
Selected References
Taguchi T et al: "Starry sky" appearance from multiple biliary hamartomas. N Engl J Med. 382(16):e33, 2020
Torbenson MS: Hamartomas and malformations of the liver. Semin Diagn Pathol. 36(1):39-47, 2019
Giambelluca D et al: The starry sky liver: multiple biliary hamartomas on MR cholangiopancreatography. Abdom Radiol (NY). 43(9):2529-30, 2018
Lin S et al: A study of multiple biliary hamartomas based on 1697 liver biopsies. Eur J Gastroenterol Hepatol. 25(8):948-52, 2013
Gil-Bello D et al: Calcification in biliary hamartomatosis. Br J Radiol. 85(1012):e99-101, 2012
Desmet VJ: Ductal plates in hepatic ductular reactions. Hypothesis and implications. III. Implications for liver pathology. Virchows Arch. 458(3):271-9, 2011
Venkatanarasimha N et al: Imaging features of ductal plate malformations in adults. Clin Radiol. 66(11):1086-93, 2011
Drenth JP et al: Congenital fibrocystic liver diseases. Best Pract Res Clin Gastroenterol. 24(5):573-84, 2010
Hughes NR et al: An immunohistochemical profile of the so-called bile duct adenoma: clues to pathogenesis. Am J Surg Pathol. 34(9):1312-8, 2010
Tohmé-Noun C et al: Multiple biliary hamartomas: magnetic resonance features with histopathologic correlation. Eur Radiol. 18(3):493-9, 2008
Orii T et al: Cholangiocarcinoma arising from preexisting biliary hamartoma of liver--report of a case. Hepatogastroenterology. 50(50):333-6, 2003
Mortele B et al: Hepatic bile duct hamartomas (von Meyenburg complexes): MR and MR cholangiography findings. J Comput Assist Tomogr. 26(3):438-43, 2002
Allgaier HP et al: Ampullary hamartoma: a rare cause of biliary obstruction. Digestion. 60(5):497-500, 1999
Semelka RC et al: Biliary hamartomas: solitary and multiple lesions shown on current MR techniques including gadolinium enhancement. J Magn Reson Imaging. 10(2):196-201, 1999
von Schweinitz D et al: Mesenchymal hamartoma of the liver--new insight into histogenesis. J Pediatr Surg. 34(8):1269-71, 1999
Cheung YC et al: MRI of multiple biliary hamartomas. Br J Radiol. 70(833):527-9, 1997
Principe A et al: Bile duct hamartomas: diagnostic problems and treatment. Hepatogastroenterology. 44(16):994-7, 1997
Iha H et al: Biliary hamartomas simulating multiple hepatic metastasis on imaging findings. Kurume Med J. 43(3):231-5, 1996
Lev-Toaff AS et al: The radiologic and pathologic spectrum of biliary hamartomas. AJR Am J Roentgenol. 165(2):309-13, 1995
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