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Biopsy Procedures
Jennifer R. Buckley, MD; Brandt C. Wible, MD
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KEY FACTS

  • Terminology

    • Preprocedure

      • Procedure

        • Post Procedure

          TERMINOLOGY

          • Definitions

            • Biopsy: Tissue acquisition from organ/lesion using large-gauge needle for microbiologic &/or pathologic analysis
              • Nonfocal (random) biopsy: Biopsy of organ parenchyma to assess diffuse disease
              • Focal (targeted) biopsy: Biopsy of discrete lesion
            • Fine-needle aspiration (FNA): Aspiration of cells from target lesion using small-gauge needle for cytologic analysis

          PREPROCEDURE

          • Indications

            • Contraindications

              • Preprocedure Imaging

                • Getting Started

                  PROCEDURE

                  • Patient Position/Location

                    • Equipment Preparation

                      • Procedure Steps

                        • Findings and Reporting

                          • Alternative Procedures/Therapies

                            POST PROCEDURE

                            • Things to Do

                              • Things to Avoid

                                OUTCOMES

                                • Problems

                                  • Complications

                                    • Expected Outcomes

                                      Selected References

                                      1. Seicean A et al: Performance of the standard 22G needle for endoscopic ultrasound-guided tissue core biopsy in pancreatic cancer. J Gastrointestin Liver Dis. 25(2):213-8, 2016
                                      2. Gellert LL et al: The diagnostic accuracy of percutaneous renal needle core biopsy and its potential impact on the clinical management of renal cortical neoplasms. Arch Pathol Lab Med. 138(12):1673-9, 2014
                                      3. Atwell TD et al: Incidence of bleeding after 15,181 percutaneous biopsies and the role of aspirin. AJR Am J Roentgenol. 194(3):784-9, 2010
                                      4. Gupta S et al: Quality improvement guidelines for percutaneous needle biopsy. J Vasc Interv Radiol. 21(7):969-75, 2010
                                      5. Gupta S et al: Image-guided percutaneous needle biopsy in cancer diagnosis and staging. Tech Vasc Interv Radiol. 10(2):88-101, 2007
                                      6. Dalal T et al: Extraadrenal pheochromocytoma: a rare cause of tachycardia and hypertension during percutaneous biopsy. AJR Am J Roentgenol. 185(2):554-5, 2005
                                      7. Gupta S et al: Various approaches for CT-guided percutaneous biopsy of deep pelvic lesions: anatomic and technical considerations. Radiographics. 24(1):175-89, 2004
                                      8. Gupta S: New techniques in image-guided percutaneous biopsy. Cardiovasc Intervent Radiol. 27(2):91-104, 2004
                                      9. Arellano RS et al: Image-guided percutaneous biopsy of the adrenal gland: review of indications, technique, and complications. Curr Probl Diagn Radiol. 32(1):3-10, 2003
                                      10. Arellano RS et al: The difficult biopsy: let's make it easier. Curr Probl Diagn Radiol. 32(5):218-26, 2003
                                      11. Cardella JF et al: Quality improvement guidelines for image-guided percutaneous biopsy in adults. J Vasc Interv Radiol. 14(9 Pt 2):S227-30, 2003
                                      12. Titton RL et al: Sonography and sonographically guided fine-needle aspiration biopsy of the thyroid gland: indications and techniques, pearls and pitfalls. AJR Am J Roentgenol. 181(1):267-71, 2003
                                      13. Lucey BC et al: Percutaneous nonvascular splenic intervention: a 10-year review. AJR Am J Roentgenol. 179(6):1591-6, 2002
                                      14. O'Neill MJ et al: Transvaginal interventional procedures: aspiration, biopsy, and catheter drainage. Radiographics. 21(3):657-72, 2001
                                      15. Wood BJ et al: Imaging guided biopsy of renal masses: indications, accuracy and impact on clinical management. J Urol. 161(5):1470-4, 1999
                                      Related Anatomy
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                                      Related Differential Diagnoses
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                                      References
                                      Tables

                                      Tables

                                      KEY FACTS

                                      • Terminology

                                        • Preprocedure

                                          • Procedure

                                            • Post Procedure

                                              TERMINOLOGY

                                              • Definitions

                                                • Biopsy: Tissue acquisition from organ/lesion using large-gauge needle for microbiologic &/or pathologic analysis
                                                  • Nonfocal (random) biopsy: Biopsy of organ parenchyma to assess diffuse disease
                                                  • Focal (targeted) biopsy: Biopsy of discrete lesion
                                                • Fine-needle aspiration (FNA): Aspiration of cells from target lesion using small-gauge needle for cytologic analysis

                                              PREPROCEDURE

                                              • Indications

                                                • Contraindications

                                                  • Preprocedure Imaging

                                                    • Getting Started

                                                      PROCEDURE

                                                      • Patient Position/Location

                                                        • Equipment Preparation

                                                          • Procedure Steps

                                                            • Findings and Reporting

                                                              • Alternative Procedures/Therapies

                                                                POST PROCEDURE

                                                                • Things to Do

                                                                  • Things to Avoid

                                                                    OUTCOMES

                                                                    • Problems

                                                                      • Complications

                                                                        • Expected Outcomes

                                                                          Selected References

                                                                          1. Seicean A et al: Performance of the standard 22G needle for endoscopic ultrasound-guided tissue core biopsy in pancreatic cancer. J Gastrointestin Liver Dis. 25(2):213-8, 2016
                                                                          2. Gellert LL et al: The diagnostic accuracy of percutaneous renal needle core biopsy and its potential impact on the clinical management of renal cortical neoplasms. Arch Pathol Lab Med. 138(12):1673-9, 2014
                                                                          3. Atwell TD et al: Incidence of bleeding after 15,181 percutaneous biopsies and the role of aspirin. AJR Am J Roentgenol. 194(3):784-9, 2010
                                                                          4. Gupta S et al: Quality improvement guidelines for percutaneous needle biopsy. J Vasc Interv Radiol. 21(7):969-75, 2010
                                                                          5. Gupta S et al: Image-guided percutaneous needle biopsy in cancer diagnosis and staging. Tech Vasc Interv Radiol. 10(2):88-101, 2007
                                                                          6. Dalal T et al: Extraadrenal pheochromocytoma: a rare cause of tachycardia and hypertension during percutaneous biopsy. AJR Am J Roentgenol. 185(2):554-5, 2005
                                                                          7. Gupta S et al: Various approaches for CT-guided percutaneous biopsy of deep pelvic lesions: anatomic and technical considerations. Radiographics. 24(1):175-89, 2004
                                                                          8. Gupta S: New techniques in image-guided percutaneous biopsy. Cardiovasc Intervent Radiol. 27(2):91-104, 2004
                                                                          9. Arellano RS et al: Image-guided percutaneous biopsy of the adrenal gland: review of indications, technique, and complications. Curr Probl Diagn Radiol. 32(1):3-10, 2003
                                                                          10. Arellano RS et al: The difficult biopsy: let's make it easier. Curr Probl Diagn Radiol. 32(5):218-26, 2003
                                                                          11. Cardella JF et al: Quality improvement guidelines for image-guided percutaneous biopsy in adults. J Vasc Interv Radiol. 14(9 Pt 2):S227-30, 2003
                                                                          12. Titton RL et al: Sonography and sonographically guided fine-needle aspiration biopsy of the thyroid gland: indications and techniques, pearls and pitfalls. AJR Am J Roentgenol. 181(1):267-71, 2003
                                                                          13. Lucey BC et al: Percutaneous nonvascular splenic intervention: a 10-year review. AJR Am J Roentgenol. 179(6):1591-6, 2002
                                                                          14. O'Neill MJ et al: Transvaginal interventional procedures: aspiration, biopsy, and catheter drainage. Radiographics. 21(3):657-72, 2001
                                                                          15. Wood BJ et al: Imaging guided biopsy of renal masses: indications, accuracy and impact on clinical management. J Urol. 161(5):1470-4, 1999