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Blastomycosis
Carlos S. Restrepo, MD; Diane C. Strollo, MD, FACR
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Pathology

          • Clinical Issues

            • Diagnostic Checklist

              TERMINOLOGY

              • Synonyms

                • North American blastomycosis
                • Chicago disease
                • Gilchrist disease
              • Definitions

                • Fungal infection with Blastomyces dermatitidis
                  • Dimorphic fungus: Disease caused by inhalation of airborne spores
                  • Found in dead, decaying, or moist material
                  • Pulmonary and disseminated forms

              IMAGING

              • General Features

                • Radiographic Findings

                  • CT Findings

                    • Imaging Recommendations

                      DIFFERENTIAL DIAGNOSIS

                        PATHOLOGY

                        • General Features

                          • Microscopic Features

                            CLINICAL ISSUES

                            • Presentation

                              • Demographics

                                • Natural History & Prognosis

                                  • Diagnosis

                                    • Treatment

                                      DIAGNOSTIC CHECKLIST

                                      • Consider

                                        Selected References

                                        1. Benedict K et al: Blastomycosis surveillance in 5 states, United States, 1987-2018. Emerg Infect Dis. 27(4), 2021
                                        2. Maini R et al: Pulmonary blastomycosis: a case series and review of unique radiological findings. Med Mycol Case Rep. 28:49-54, 2020
                                        3. Schwartz IS et al: Blastomycosis. Semin Respir Crit Care Med. 41(1):31-41, 2020
                                        4. Rozovsky K et al: Imaging patterns of pediatric pulmonary blastomycosis. AJR Am J Roentgenol. 212(4):905-13, 2019
                                        5. Ronald S et al: Computed tomographic scan evaluation of pulmonary blastomycosis. Can J Infect Dis Med Microbiol. 20(4):112-6, 2009
                                        6. Fang W et al: Imaging manifestations of blastomycosis: a pulmonary infection with potential dissemination. Radiographics. 27(3):641-55, 2007
                                        7. Bradsher RW et al: Blastomycosis. Infect Dis Clin North Am. 17(1):21-40, vii, 2003
                                        Related Anatomy
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                                        Related Differential Diagnoses
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                                        References
                                        Tables

                                        Tables

                                        KEY FACTS

                                        • Terminology

                                          • Imaging

                                            • Top Differential Diagnoses

                                              • Pathology

                                                • Clinical Issues

                                                  • Diagnostic Checklist

                                                    TERMINOLOGY

                                                    • Synonyms

                                                      • North American blastomycosis
                                                      • Chicago disease
                                                      • Gilchrist disease
                                                    • Definitions

                                                      • Fungal infection with Blastomyces dermatitidis
                                                        • Dimorphic fungus: Disease caused by inhalation of airborne spores
                                                        • Found in dead, decaying, or moist material
                                                        • Pulmonary and disseminated forms

                                                    IMAGING

                                                    • General Features

                                                      • Radiographic Findings

                                                        • CT Findings

                                                          • Imaging Recommendations

                                                            DIFFERENTIAL DIAGNOSIS

                                                              PATHOLOGY

                                                              • General Features

                                                                • Microscopic Features

                                                                  CLINICAL ISSUES

                                                                  • Presentation

                                                                    • Demographics

                                                                      • Natural History & Prognosis

                                                                        • Diagnosis

                                                                          • Treatment

                                                                            DIAGNOSTIC CHECKLIST

                                                                            • Consider

                                                                              Selected References

                                                                              1. Benedict K et al: Blastomycosis surveillance in 5 states, United States, 1987-2018. Emerg Infect Dis. 27(4), 2021
                                                                              2. Maini R et al: Pulmonary blastomycosis: a case series and review of unique radiological findings. Med Mycol Case Rep. 28:49-54, 2020
                                                                              3. Schwartz IS et al: Blastomycosis. Semin Respir Crit Care Med. 41(1):31-41, 2020
                                                                              4. Rozovsky K et al: Imaging patterns of pediatric pulmonary blastomycosis. AJR Am J Roentgenol. 212(4):905-13, 2019
                                                                              5. Ronald S et al: Computed tomographic scan evaluation of pulmonary blastomycosis. Can J Infect Dis Med Microbiol. 20(4):112-6, 2009
                                                                              6. Fang W et al: Imaging manifestations of blastomycosis: a pulmonary infection with potential dissemination. Radiographics. 27(3):641-55, 2007
                                                                              7. Bradsher RW et al: Blastomycosis. Infect Dis Clin North Am. 17(1):21-40, vii, 2003