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Bone Infarction
Jeffrey S. Ross, MD
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Diagnostic Checklist

          TERMINOLOGY

          • Synonyms

            • Immature bone infarct, bone marrow infarction
          • Definitions

            • Infarction of vertebral body cancellous bone and marrow secondary to systemic disease or aortic pathology
            • Not osteonecrosis (Kümmell disease)

          IMAGING

          • General Features

            • Radiographic Findings

              • CT Findings

                • MR Findings

                  DIFFERENTIAL DIAGNOSIS

                    PATHOLOGY

                    • Gross Pathologic & Surgical Features

                      CLINICAL ISSUES

                      • Presentation

                        DIAGNOSTIC CHECKLIST

                        • Consider

                          Selected References

                          1. Watanabe M et al: Craniofacial bone infarcts in sickle cell disease: clinical and radiological manifestations. J Comput Assist Tomogr. 37(1):91-7, 2013
                          2. Shah LM et al: MRI of spinal bone marrow: part I, techniques and normal age-related appearances. AJR Am J Roentgenol. 197(6):1298-308, 2011
                          3. Tall MA et al: MR imaging of the spinal bone marrow. Magn Reson Imaging Clin N Am. 15(2):175-98, vi, 2007
                          4. Alyas F et al: MR imaging evaluation of the bone marrow and marrow infiltrative disorders of the lumbar spine. Magn Reson Imaging Clin N Am. 15(2):199-219, vi, 2007
                          5. Vazquez E et al: Neuroimaging in pediatric leukemia and lymphoma: differential diagnosis. Radiographics. 22(6):1411-28, 2002
                          6. Mori A et al: Avascular necrosis in the femoral head secondary to bone marrow infarction in a patient with graft-versus-host disease after unrelated bone marrow transplantation. Ann Hematol. 80(4):238-42, 2001
                          7. Butt WP: MRI diagnosis of bone marrow infarction in the child with leukaemia. Clin Radiol. 53(1):77, 1998
                          8. Mori A et al: Bone marrow infarction due to acute graft-versus-host disease in an acute lymphoblastic leukemia patient after unrelated bone marrow transplantation. Bone Marrow Transplant. 21(6):615-7, 1998
                          9. Amano Y et al: Case report: the MRI diagnosis of bone marrow infarction in a child with leukaemia. Clin Radiol. 52(7):560-2, 1997
                          10. Munk PL et al: Immature bone infarcts: findings on plain radiographs and MR scans. AJR Am J Roentgenol. 152(3):547-9, 1989
                          11. Bain B: Extensive bone marrow infarction followed by myelofibrosis in patient with Ph' positive chronic granulocytic leukaemia. J Clin Pathol. 33(5):449-53, 1980
                          Related Anatomy
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                          Related Differential Diagnoses
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                          References
                          Tables

                          Tables

                          KEY FACTS

                          • Terminology

                            • Imaging

                              • Top Differential Diagnoses

                                • Diagnostic Checklist

                                  TERMINOLOGY

                                  • Synonyms

                                    • Immature bone infarct, bone marrow infarction
                                  • Definitions

                                    • Infarction of vertebral body cancellous bone and marrow secondary to systemic disease or aortic pathology
                                    • Not osteonecrosis (Kümmell disease)

                                  IMAGING

                                  • General Features

                                    • Radiographic Findings

                                      • CT Findings

                                        • MR Findings

                                          DIFFERENTIAL DIAGNOSIS

                                            PATHOLOGY

                                            • Gross Pathologic & Surgical Features

                                              CLINICAL ISSUES

                                              • Presentation

                                                DIAGNOSTIC CHECKLIST

                                                • Consider

                                                  Selected References

                                                  1. Watanabe M et al: Craniofacial bone infarcts in sickle cell disease: clinical and radiological manifestations. J Comput Assist Tomogr. 37(1):91-7, 2013
                                                  2. Shah LM et al: MRI of spinal bone marrow: part I, techniques and normal age-related appearances. AJR Am J Roentgenol. 197(6):1298-308, 2011
                                                  3. Tall MA et al: MR imaging of the spinal bone marrow. Magn Reson Imaging Clin N Am. 15(2):175-98, vi, 2007
                                                  4. Alyas F et al: MR imaging evaluation of the bone marrow and marrow infiltrative disorders of the lumbar spine. Magn Reson Imaging Clin N Am. 15(2):199-219, vi, 2007
                                                  5. Vazquez E et al: Neuroimaging in pediatric leukemia and lymphoma: differential diagnosis. Radiographics. 22(6):1411-28, 2002
                                                  6. Mori A et al: Avascular necrosis in the femoral head secondary to bone marrow infarction in a patient with graft-versus-host disease after unrelated bone marrow transplantation. Ann Hematol. 80(4):238-42, 2001
                                                  7. Butt WP: MRI diagnosis of bone marrow infarction in the child with leukaemia. Clin Radiol. 53(1):77, 1998
                                                  8. Mori A et al: Bone marrow infarction due to acute graft-versus-host disease in an acute lymphoblastic leukemia patient after unrelated bone marrow transplantation. Bone Marrow Transplant. 21(6):615-7, 1998
                                                  9. Amano Y et al: Case report: the MRI diagnosis of bone marrow infarction in a child with leukaemia. Clin Radiol. 52(7):560-2, 1997
                                                  10. Munk PL et al: Immature bone infarcts: findings on plain radiographs and MR scans. AJR Am J Roentgenol. 152(3):547-9, 1989
                                                  11. Bain B: Extensive bone marrow infarction followed by myelofibrosis in patient with Ph' positive chronic granulocytic leukaemia. J Clin Pathol. 33(5):449-53, 1980