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Spine
Differential Diagnosis
Vertebral Body - Posterior Elements
Generic Imaging Patterns
Bony Lesion, Aggressive
Bony Lesion, Aggressive
Jeffrey S. Ross, MD; Lubdha M. Shah, MD
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DIFFERENTIAL DIAGNOSIS

    ESSENTIAL INFORMATION

    • Key Differential Diagnosis Issues

      • Helpful Clues for Common Diagnoses

        • Helpful Clues for Less Common Diagnoses

          • Helpful Clues for Rare Diagnoses

            Selected References

            1. Oitment C et al: Primary sarcomas of the spine: population-based demographic and survival data in 107 spinal sarcomas over a 23-year period in Ontario, Canada. Spine J. 21(2):296-301, 2021
            2. Moussalem CK et al: Spinal sarcomas and immunity: an undervalued relationship. Semin Cancer Biol. 64:36-50, 2020
            3. Kim CJ et al: Vertebral osteomyelitis caused by non-tuberculous mycobacteria: predisposing conditions and clinical characteristics of six cases and a review of 63 cases in the literature. Infect Dis (Lond). 1-8, 2016
            4. Ledbetter LN et al: Spinal neuroarthropathy: pathophysiology, clinical and imaging features, and differential diagnosis. Radiographics. 150121, 2016
            5. Lin J et al: Influence of hormone receptor status on spinal metastatic lesions in patients with breast cancer. World Neurosurg. 85:42-8, 2016
            6. Nickerson EK et al: Vertebral osteomyelitis in adults: an update. Br Med Bull. 117(1):121-38, 2016
            7. Shoji H et al: Clinical features, outcomes, and survival factor in patients with vertebral osteomyelitis infected by methicillin-resistant staphylococci. J Orthop Sci. 21(3):282-6, 2016
            8. Sigwalt L et al: A thoracic spinal bone giant cell tumor in a skeletally immature girl. A case report and literature review. Childs Nerv Syst. 32(5):873-6, 2016
            9. Issa M et al: Vertebroplasty for vertebral hemangioma in children: a report of two cases with 2-year follow-up. Childs Nerv Syst. 31(11):2179-83, 2015
            10. Mahajan PS et al: Rare case of multiple aggressive vertebral hemangiomas. J Nat Sci Biol Med. 6(2):439-42, 2015
            11. Boriani S et al: Aneurysmal bone cysts of the spine: treatment options and considerations. J Neurooncol. 120(1):171-8, 2014
            12. Chan-Seng E et al: Spinal metastases in breast cancer: single center experience. World Neurosurg. 82(6):1344-50, 2014
            13. Jiang L et al: Diagnosis and treatment of vertebral hemangiomas with neurologic deficit: a report of 29 cases and literature review. Spine J. 14(6):944-54, 2014
            14. Lee SK et al: Solitary Langerhans cell histocytosis of skull and spine in pediatric and adult patients. Childs Nerv Syst. 30(2):271-5, 2014
            15. Zhang P et al: Hemangiopericytoma of the cervicothoracic spine: a case report and literature review. Turk Neurosurg. 24(6):948-53, 2014
            16. Singh DK et al: Aggressive osteoblastoma involving the craniovertebral junction: A case report and review of literature. J Craniovertebr Junction Spine. 4(2):69-72, 2013
            17. Alexander J et al: Vertebral hemangioma: an important differential in the evaluation of locally aggressive spinal lesions. Spine (Phila Pa 1976). 35(18):E917-20, 2010
            Related Anatomy
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            References
            Tables

            Tables

            DIFFERENTIAL DIAGNOSIS

              ESSENTIAL INFORMATION

              • Key Differential Diagnosis Issues

                • Helpful Clues for Common Diagnoses

                  • Helpful Clues for Less Common Diagnoses

                    • Helpful Clues for Rare Diagnoses

                      Selected References

                      1. Oitment C et al: Primary sarcomas of the spine: population-based demographic and survival data in 107 spinal sarcomas over a 23-year period in Ontario, Canada. Spine J. 21(2):296-301, 2021
                      2. Moussalem CK et al: Spinal sarcomas and immunity: an undervalued relationship. Semin Cancer Biol. 64:36-50, 2020
                      3. Kim CJ et al: Vertebral osteomyelitis caused by non-tuberculous mycobacteria: predisposing conditions and clinical characteristics of six cases and a review of 63 cases in the literature. Infect Dis (Lond). 1-8, 2016
                      4. Ledbetter LN et al: Spinal neuroarthropathy: pathophysiology, clinical and imaging features, and differential diagnosis. Radiographics. 150121, 2016
                      5. Lin J et al: Influence of hormone receptor status on spinal metastatic lesions in patients with breast cancer. World Neurosurg. 85:42-8, 2016
                      6. Nickerson EK et al: Vertebral osteomyelitis in adults: an update. Br Med Bull. 117(1):121-38, 2016
                      7. Shoji H et al: Clinical features, outcomes, and survival factor in patients with vertebral osteomyelitis infected by methicillin-resistant staphylococci. J Orthop Sci. 21(3):282-6, 2016
                      8. Sigwalt L et al: A thoracic spinal bone giant cell tumor in a skeletally immature girl. A case report and literature review. Childs Nerv Syst. 32(5):873-6, 2016
                      9. Issa M et al: Vertebroplasty for vertebral hemangioma in children: a report of two cases with 2-year follow-up. Childs Nerv Syst. 31(11):2179-83, 2015
                      10. Mahajan PS et al: Rare case of multiple aggressive vertebral hemangiomas. J Nat Sci Biol Med. 6(2):439-42, 2015
                      11. Boriani S et al: Aneurysmal bone cysts of the spine: treatment options and considerations. J Neurooncol. 120(1):171-8, 2014
                      12. Chan-Seng E et al: Spinal metastases in breast cancer: single center experience. World Neurosurg. 82(6):1344-50, 2014
                      13. Jiang L et al: Diagnosis and treatment of vertebral hemangiomas with neurologic deficit: a report of 29 cases and literature review. Spine J. 14(6):944-54, 2014
                      14. Lee SK et al: Solitary Langerhans cell histocytosis of skull and spine in pediatric and adult patients. Childs Nerv Syst. 30(2):271-5, 2014
                      15. Zhang P et al: Hemangiopericytoma of the cervicothoracic spine: a case report and literature review. Turk Neurosurg. 24(6):948-53, 2014
                      16. Singh DK et al: Aggressive osteoblastoma involving the craniovertebral junction: A case report and review of literature. J Craniovertebr Junction Spine. 4(2):69-72, 2013
                      17. Alexander J et al: Vertebral hemangioma: an important differential in the evaluation of locally aggressive spinal lesions. Spine (Phila Pa 1976). 35(18):E917-20, 2010