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Brain Death
Anne G. Osborn, MD, FACR
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Pathology

          • Clinical Issues

            TERMINOLOGY

            • Abbreviations

              • Brain death (BD); death by neurological criteria (DNC)
            • Definitions

              • Complete, irreversible cessation of brain function

            IMAGING

            • General Features

              • CT Findings

                • MR Findings

                  • Ultrasonographic Findings

                    • Angiographic Findings

                      • Nuclear Medicine Findings

                        • Other Modality Findings

                          • Imaging Recommendations

                            DIFFERENTIAL DIAGNOSIS

                              PATHOLOGY

                              • General Features

                                • Gross Pathologic & Surgical Features

                                  CLINICAL ISSUES

                                  • Presentation

                                    Selected References

                                    1. Burkle CM et al: Why brain death is considered death and why there should be no confusion. Neurology. 83(16):1464-9, 2014
                                    2. Flamm AL et al: Family members' requests to extend physiologic support after declaration of brain death: a case series analysis and proposed guidelines for clinical management. J Clin Ethics. 25(3):222-37, 2014
                                    3. Shemie SD et al: International guideline development for the determination of death. Intensive Care Med. 40(6):788-97, 2014
                                    4. Taylor T et al: Computed tomography (CT) angiography for confirmation of the clinical diagnosis of brain death. Cochrane Database Syst Rev. 3:CD009694, 2014
                                    5. Spinello IM: Brain Death Determination. J Intensive Care Med. ePub, 2013
                                    6. Wijdicks EF et al: Evidence-based guideline update: determining brain death in adults: report of the Quality Standards Subcommittee of the American Academy of Neurology. Neurology. 74(23):1911-8, 2010
                                    7. Wijman CA et al: Prognostic value of brain diffusion-weighted imaging after cardiac arrest. Ann Neurol. 65(4):394-402, 2009
                                    Related Anatomy
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                                    Related Differential Diagnoses
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                                    References
                                    Tables

                                    Tables

                                    KEY FACTS

                                    • Terminology

                                      • Imaging

                                        • Top Differential Diagnoses

                                          • Pathology

                                            • Clinical Issues

                                              TERMINOLOGY

                                              • Abbreviations

                                                • Brain death (BD); death by neurological criteria (DNC)
                                              • Definitions

                                                • Complete, irreversible cessation of brain function

                                              IMAGING

                                              • General Features

                                                • CT Findings

                                                  • MR Findings

                                                    • Ultrasonographic Findings

                                                      • Angiographic Findings

                                                        • Nuclear Medicine Findings

                                                          • Other Modality Findings

                                                            • Imaging Recommendations

                                                              DIFFERENTIAL DIAGNOSIS

                                                                PATHOLOGY

                                                                • General Features

                                                                  • Gross Pathologic & Surgical Features

                                                                    CLINICAL ISSUES

                                                                    • Presentation

                                                                      Selected References

                                                                      1. Burkle CM et al: Why brain death is considered death and why there should be no confusion. Neurology. 83(16):1464-9, 2014
                                                                      2. Flamm AL et al: Family members' requests to extend physiologic support after declaration of brain death: a case series analysis and proposed guidelines for clinical management. J Clin Ethics. 25(3):222-37, 2014
                                                                      3. Shemie SD et al: International guideline development for the determination of death. Intensive Care Med. 40(6):788-97, 2014
                                                                      4. Taylor T et al: Computed tomography (CT) angiography for confirmation of the clinical diagnosis of brain death. Cochrane Database Syst Rev. 3:CD009694, 2014
                                                                      5. Spinello IM: Brain Death Determination. J Intensive Care Med. ePub, 2013
                                                                      6. Wijdicks EF et al: Evidence-based guideline update: determining brain death in adults: report of the Quality Standards Subcommittee of the American Academy of Neurology. Neurology. 74(23):1911-8, 2010
                                                                      7. Wijman CA et al: Prognostic value of brain diffusion-weighted imaging after cardiac arrest. Ann Neurol. 65(4):394-402, 2009