Nonneoplastic hyperplasia of duodenal submucosal glands
Diffuse type (Brunner gland hyperplasia)
Multiple, small, submucosal nodules < 5 mm
Solitary type (Brunner gland hamartoma)
Solitary sessile or pedunculated lesion > 5 mm
IMAGING
General Features
MR Findings
Imaging Recommendations
Fluoroscopic Findings
Ultrasonographic Findings
CT Findings
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Treatment
Selected References
Patel BN et al: Groove pancreatitis: a clinical and imaging overview. Abdom Radiol (NY). 45(5):1439-46, 2020
Barat M et al: Mass-forming lesions of the duodenum: a pictorial review. Diagn Interv Imaging. 98(10):663-75, 2017
Chen KM et al: A duodenal tumor with intermittent obstruction. Brunner's gland hyperplasia. Gastroenterology. 146(4):e7-8, 2014
Kim K et al: Clinicopathologic characteristics and mucin expression in Brunner's gland proliferating lesions. Dig Dis Sci. 58(1):194-201, 2013
Pavlovic Markovic A et al: Endoscopic ultrasound for differential diagnosis of duodenal lesions. Ultraschall Med. 33(7):E210-7, 2012
Kini JR et al: Brunner's gland hamartoma and hyperplasia. Trop Gastroenterol. 31(2):121-3, 2010
Calva D et al: Hamartomatous polyposis syndromes. Surg Clin North Am. 88(4):779-817, vii, 2008
Hosogi H et al: Molecular insights into Peutz-Jeghers syndrome: two probands with a germline mutation of LKB1. J Gastroenterol. 43(6):492-7, 2008
Patel ND et al: Brunner's gland hyperplasia and hamartoma: imaging features with clinicopathologic correlation. AJR Am J Roentgenol. 187(3):715-22, 2006
Nonneoplastic hyperplasia of duodenal submucosal glands
Diffuse type (Brunner gland hyperplasia)
Multiple, small, submucosal nodules < 5 mm
Solitary type (Brunner gland hamartoma)
Solitary sessile or pedunculated lesion > 5 mm
IMAGING
General Features
MR Findings
Imaging Recommendations
Fluoroscopic Findings
Ultrasonographic Findings
CT Findings
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Treatment
Selected References
Patel BN et al: Groove pancreatitis: a clinical and imaging overview. Abdom Radiol (NY). 45(5):1439-46, 2020
Barat M et al: Mass-forming lesions of the duodenum: a pictorial review. Diagn Interv Imaging. 98(10):663-75, 2017
Chen KM et al: A duodenal tumor with intermittent obstruction. Brunner's gland hyperplasia. Gastroenterology. 146(4):e7-8, 2014
Kim K et al: Clinicopathologic characteristics and mucin expression in Brunner's gland proliferating lesions. Dig Dis Sci. 58(1):194-201, 2013
Pavlovic Markovic A et al: Endoscopic ultrasound for differential diagnosis of duodenal lesions. Ultraschall Med. 33(7):E210-7, 2012
Kini JR et al: Brunner's gland hamartoma and hyperplasia. Trop Gastroenterol. 31(2):121-3, 2010
Calva D et al: Hamartomatous polyposis syndromes. Surg Clin North Am. 88(4):779-817, vii, 2008
Hosogi H et al: Molecular insights into Peutz-Jeghers syndrome: two probands with a germline mutation of LKB1. J Gastroenterol. 43(6):492-7, 2008
Patel ND et al: Brunner's gland hyperplasia and hamartoma: imaging features with clinicopathologic correlation. AJR Am J Roentgenol. 187(3):715-22, 2006
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