Benign, locally aggressive fibroblastic lesion of childhood; usually on distal extremities
Characterized by bland spindle cells and less cellular zones of calcification with plump epithelioid fibroblasts
IMAGING
General Features
Imaging Recommendations
Radiographic Findings
CT Findings
MR Findings
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
Selected References
Kao YC et al: What is new about the molecular genetics in matrix-producing soft tissue tumors? The contributions to pathogenetic understanding and diagnostic classification. Virchows Arch. 476(1):121-34, 2020
Puls F et al: Calcifying aponeurotic fibroma. In Fletcher CDM et al: WHO Classification of Tumours: Soft Tissue and Bone Tumours. 5th ed. IARC Press. 74-5, 2020
Kwee RM et al: Calcified or ossified benign soft tissue lesions that may simulate malignancy. Skeletal Radiol. 48(12):1875-90, 2019
Shim SW et al: MRI features of calcifying aponeurotic fibroma in the upper arm: a case report and review of the literature. Skeletal Radiol. 45(8):1139-43, 2016
Cho YH et al: Calcifying aponeurotic fibroma of the dorsum of the foot: radiographic and magnetic resonance imaging findings in a four-year-old boy. Iran J Radiol. 12(2):e23911, 2015
Kransdorf MJ et al: Fibrous and fibrohistiocytic tumors. In Kransdorf MJ et al: Imaging of Soft Tissue Tumors. 3rd ed. Lippincott Williams & Wilkins. 261-2, 2014
Kim OH et al: Calcifying aponeurotic fibroma: case report with radiographic and MR features. Korean J Radiol. 15(1):134-9, 2014
Murphey MD et al: From the archives of the AFIP: musculoskeletal fibromatoses: radiologic-pathologic correlation. Radiographics. 29(7):2143-73, 2009
Weiss SW et al: Fibrous tumors of infancy and childhood. In Weiss SW et al: Enzinger and Weiss' Soft Tissue Tumors. 5th ed. Elsevier. 289-93, 2008
Kim DH et al: Acute median-nerve compression caused by calcifying aponeurotic fibroma. Am J Phys Med Rehabil. 85(12):1017-8, 2006
Parker WL et al: Calcifying aponeurotic fibroma of the hand: radiologic differentiation from giant cell tumors of the tendon sheath. J Hand Surg Am. 31(6):1024-8, 2006
Kwak HS et al: MR imaging of calcifying aponeurotic fibroma of the thigh. Pediatr Radiol. 34(5):438-40, 2004
Farshid G et al: Calcifying aponeurotic fibroma. In Fletcher CDM et al: WHO Classification of Tumours. Pathology and Genetics of Tumours of Soft Tissue and Bone. IARC Press. 69-70, 2002
Fetsch JF et al: Calcifying aponeurotic fibroma: a clinicopathologic study of 22 cases arising in uncommon sites. Hum Pathol. 29(12):1504-10, 1998
Related Anatomy
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Related Differential Diagnoses
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References
Tables
Tables
KEY FACTS
Terminology
Imaging
Pathology
Clinical Issues
TERMINOLOGY
Synonyms
Juvenile aponeurotic fibroma, aponeurotic fibroma
Definitions
Benign, locally aggressive fibroblastic lesion of childhood; usually on distal extremities
Characterized by bland spindle cells and less cellular zones of calcification with plump epithelioid fibroblasts
IMAGING
General Features
Imaging Recommendations
Radiographic Findings
CT Findings
MR Findings
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
Selected References
Kao YC et al: What is new about the molecular genetics in matrix-producing soft tissue tumors? The contributions to pathogenetic understanding and diagnostic classification. Virchows Arch. 476(1):121-34, 2020
Puls F et al: Calcifying aponeurotic fibroma. In Fletcher CDM et al: WHO Classification of Tumours: Soft Tissue and Bone Tumours. 5th ed. IARC Press. 74-5, 2020
Kwee RM et al: Calcified or ossified benign soft tissue lesions that may simulate malignancy. Skeletal Radiol. 48(12):1875-90, 2019
Shim SW et al: MRI features of calcifying aponeurotic fibroma in the upper arm: a case report and review of the literature. Skeletal Radiol. 45(8):1139-43, 2016
Cho YH et al: Calcifying aponeurotic fibroma of the dorsum of the foot: radiographic and magnetic resonance imaging findings in a four-year-old boy. Iran J Radiol. 12(2):e23911, 2015
Kransdorf MJ et al: Fibrous and fibrohistiocytic tumors. In Kransdorf MJ et al: Imaging of Soft Tissue Tumors. 3rd ed. Lippincott Williams & Wilkins. 261-2, 2014
Kim OH et al: Calcifying aponeurotic fibroma: case report with radiographic and MR features. Korean J Radiol. 15(1):134-9, 2014
Murphey MD et al: From the archives of the AFIP: musculoskeletal fibromatoses: radiologic-pathologic correlation. Radiographics. 29(7):2143-73, 2009
Weiss SW et al: Fibrous tumors of infancy and childhood. In Weiss SW et al: Enzinger and Weiss' Soft Tissue Tumors. 5th ed. Elsevier. 289-93, 2008
Kim DH et al: Acute median-nerve compression caused by calcifying aponeurotic fibroma. Am J Phys Med Rehabil. 85(12):1017-8, 2006
Parker WL et al: Calcifying aponeurotic fibroma of the hand: radiologic differentiation from giant cell tumors of the tendon sheath. J Hand Surg Am. 31(6):1024-8, 2006
Kwak HS et al: MR imaging of calcifying aponeurotic fibroma of the thigh. Pediatr Radiol. 34(5):438-40, 2004
Farshid G et al: Calcifying aponeurotic fibroma. In Fletcher CDM et al: WHO Classification of Tumours. Pathology and Genetics of Tumours of Soft Tissue and Bone. IARC Press. 69-70, 2002
Fetsch JF et al: Calcifying aponeurotic fibroma: a clinicopathologic study of 22 cases arising in uncommon sites. Hum Pathol. 29(12):1504-10, 1998
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