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Cardiovascular Disorders
Cardiovascular Neoplasms
Cardiac Lymphoma
Cardiac Lymphoma
John P. Lichtenberger, III, MD
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KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Clinical Issues
Diagnostic Checklist
TERMINOLOGY
Abbreviations
Non-Hodgkin lymphoma (NHL)
Definitions
Primary cardiac lymphoma (PCL)
Confined to heart and pericardium without extracardiac disease
Rare; majority occur in patients with HIV/AIDS
Secondary cardiac lymphoma (SCL)
Cardiac involvement in patients with systemic lymphoma
~ 1/3 of patients with lymphoma develop secondary cardiac lymphoma (pathology series)
Primary effusion lymphoma (PEL)
Rare; HIV-associated NHL
Lymphomatous growth in liquid phase in body cavities, such as pericardium
Evidence of infection by human herpesvirus-8, which is associated with Kaposi sarcoma
IMAGING
General Features
Radiographic Findings
CT Findings
MR Findings
Echocardiographic Findings
Imaging Recommendations
Nuclear Medicine Findings
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Image Interpretation Pearls
Selected References
Carter BW et al: Multimodality imaging of cardiothoracic lymphoma. Eur J Radiol. 83(8):1470-82, 2014
Miller PE et al: The drowning heart: an ambiguous lymphoma. Am J Med. 127(9):817-9, 2014
Jeudy J et al: From the radiologic pathology archives: cardiac lymphoma: radiologic-pathologic correlation. Radiographics. 32(5):1369-80, 2012
Shah RN et al: Primary cardiac lymphoma diagnosed by multiphase-gated cardiac CT and CT-guided percutaneous trans-sternal biopsy. J Cardiovasc Comput Tomogr. 6(2):137-9, 2012
Paes FM et al: FDG PET/CT of extranodal involvement in non-Hodgkin lymphoma and Hodgkin disease. Radiographics. 30(1):269-91, 2010
Related Anatomy
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Related Differential Diagnoses
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References
Tables
Tables
KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Clinical Issues
Diagnostic Checklist
TERMINOLOGY
Abbreviations
Non-Hodgkin lymphoma (NHL)
Definitions
Primary cardiac lymphoma (PCL)
Confined to heart and pericardium without extracardiac disease
Rare; majority occur in patients with HIV/AIDS
Secondary cardiac lymphoma (SCL)
Cardiac involvement in patients with systemic lymphoma
~ 1/3 of patients with lymphoma develop secondary cardiac lymphoma (pathology series)
Primary effusion lymphoma (PEL)
Rare; HIV-associated NHL
Lymphomatous growth in liquid phase in body cavities, such as pericardium
Evidence of infection by human herpesvirus-8, which is associated with Kaposi sarcoma
IMAGING
General Features
Radiographic Findings
CT Findings
MR Findings
Echocardiographic Findings
Imaging Recommendations
Nuclear Medicine Findings
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Image Interpretation Pearls
Selected References
Carter BW et al: Multimodality imaging of cardiothoracic lymphoma. Eur J Radiol. 83(8):1470-82, 2014
Miller PE et al: The drowning heart: an ambiguous lymphoma. Am J Med. 127(9):817-9, 2014
Jeudy J et al: From the radiologic pathology archives: cardiac lymphoma: radiologic-pathologic correlation. Radiographics. 32(5):1369-80, 2012
Shah RN et al: Primary cardiac lymphoma diagnosed by multiphase-gated cardiac CT and CT-guided percutaneous trans-sternal biopsy. J Cardiovasc Comput Tomogr. 6(2):137-9, 2012
Paes FM et al: FDG PET/CT of extranodal involvement in non-Hodgkin lymphoma and Hodgkin disease. Radiographics. 30(1):269-91, 2010
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