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KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Pathology
Clinical Issues
TERMINOLOGY
Definitions
- Most common primary cardiac malignancy
- Restricted to heart and pericardium
- Cardiac tumors that arise from one of connective tissues (mesodermal cell origin) of heart
Types of Cardiac Sarcoma
- Angiosarcoma, undifferentiated sarcomas, malignant fibrous histiocytoma (MFH), osteosarcoma, leiomyosarcoma, myxofibrosarcoma, synovial sarcoma, rhabdomyosarcoma
IMAGING
General Features
Radiographic Findings
CT Findings
MR Findings
Ultrasonographic Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Staging, Grading, & Classification
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Selected References
- Caspar T et al: Magnetic resonance evaluation of cardiac thrombi and masses by T1 and T2 mapping: an observational study. Int J Cardiovasc Imaging. 33(4):551-9, 2017
- Tüdös Z et al: "Sun ray" appearance in a case of cardiac angiosarcoma: a comparison of MRI and PET/CT. Magn Reson Med Sci. 16(2):176-80, 2017
- Hudzik B et al: Malignant tumors of the heart. Cancer Epidemiol. 39(5):665-72, 2015
- Trimble CR et al: Primary cardiac osteosarcoma: airp best cases in radiologic-pathologic correlation. Radiographics. 35(5):1352-7, 2015
- Esposito A et al: CMR in the assessment of cardiac masses: primary malignant tumors. JACC Cardiovasc Imaging. 7(10):1057-61, 2014
- Look Hong NJ et al: Cardiac angiosarcoma management and outcomes: 20-year single-institution experience. Ann Surg Oncol. 19(8):2707-15, 2012
- Bendel EC et al: Imaging sarcomas of the great vessels and heart. Semin Ultrasound CT MR. 32(5):377-404, 2011
- Buckley O et al: Cardiac masses, part 2: key imaging features for diagnosis and surgical planning. AJR Am J Roentgenol. 197(5):W842-51, 2011
- Hashimoto W et al: Primary cardiac osteosarcoma with imaging that revealed no calcification. Gen Thorac Cardiovasc Surg. 59(3):184-6, 2011
- Randhawa K et al: Magnetic resonance imaging of cardiac tumors: part 2, malignant tumors and tumor-like conditions. Curr Probl Diagn Radiol. 40(4):169-79, 2011
- Serdaroglu G et al: A rare cause of recurrent stroke in childhood: left atrial rhabdomyosarcoma. Acta Paediatr. 100(10):e189-91, 2011
- Fresneau B et al: [Malignant primary cardiac tumors in childhood and adolescence.] Arch Pediatr. 17(5):495-501, 2010
- O'Donnell DH et al: Cardiac tumors: optimal cardiac MR sequences and spectrum of imaging appearances. AJR Am J Roentgenol. 193(2):377-87, 2009
- Truong PT et al: Treatment and outcomes in adult patients with primary cardiac sarcoma: the British Columbia Cancer Agency experience. Ann Surg Oncol. 16(12):3358-65, 2009
- Murinello A et al: Cardiac angiosarcoma--a review. Rev Port Cardiol. 26(5):577-84, 2007
- Sparrow PJ et al: MR imaging of cardiac tumors. Radiographics. 25(5):1255-76, 2005
- Best AK et al: Best cases from the AFIP: cardiac angiosarcoma. Radiographics. 23 Spec No:S141-5, 2003
- Chiles C et al: Metastatic involvement of the heart and pericardium: CT and MR imaging. Radiographics. 21(2):439-49, 2001
- Araoz PA et al: CT and MR imaging of benign primary cardiac neoplasms with echocardiographic correlation. Radiographics. 20(5):1303-19, 2000
- Grebenc ML et al: Primary cardiac and pericardial neoplasms: radiologic-pathologic correlation. Radiographics. 20(4):1073-103; quiz 1110-1, 1112, 2000
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References
Tables
Tables
KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Pathology
Clinical Issues
TERMINOLOGY
Definitions
- Most common primary cardiac malignancy
- Restricted to heart and pericardium
- Cardiac tumors that arise from one of connective tissues (mesodermal cell origin) of heart
Types of Cardiac Sarcoma
- Angiosarcoma, undifferentiated sarcomas, malignant fibrous histiocytoma (MFH), osteosarcoma, leiomyosarcoma, myxofibrosarcoma, synovial sarcoma, rhabdomyosarcoma
IMAGING
General Features
Radiographic Findings
CT Findings
MR Findings
Ultrasonographic Findings
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Staging, Grading, & Classification
Gross Pathologic & Surgical Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Consider
Selected References
- Caspar T et al: Magnetic resonance evaluation of cardiac thrombi and masses by T1 and T2 mapping: an observational study. Int J Cardiovasc Imaging. 33(4):551-9, 2017
- Tüdös Z et al: "Sun ray" appearance in a case of cardiac angiosarcoma: a comparison of MRI and PET/CT. Magn Reson Med Sci. 16(2):176-80, 2017
- Hudzik B et al: Malignant tumors of the heart. Cancer Epidemiol. 39(5):665-72, 2015
- Trimble CR et al: Primary cardiac osteosarcoma: airp best cases in radiologic-pathologic correlation. Radiographics. 35(5):1352-7, 2015
- Esposito A et al: CMR in the assessment of cardiac masses: primary malignant tumors. JACC Cardiovasc Imaging. 7(10):1057-61, 2014
- Look Hong NJ et al: Cardiac angiosarcoma management and outcomes: 20-year single-institution experience. Ann Surg Oncol. 19(8):2707-15, 2012
- Bendel EC et al: Imaging sarcomas of the great vessels and heart. Semin Ultrasound CT MR. 32(5):377-404, 2011
- Buckley O et al: Cardiac masses, part 2: key imaging features for diagnosis and surgical planning. AJR Am J Roentgenol. 197(5):W842-51, 2011
- Hashimoto W et al: Primary cardiac osteosarcoma with imaging that revealed no calcification. Gen Thorac Cardiovasc Surg. 59(3):184-6, 2011
- Randhawa K et al: Magnetic resonance imaging of cardiac tumors: part 2, malignant tumors and tumor-like conditions. Curr Probl Diagn Radiol. 40(4):169-79, 2011
- Serdaroglu G et al: A rare cause of recurrent stroke in childhood: left atrial rhabdomyosarcoma. Acta Paediatr. 100(10):e189-91, 2011
- Fresneau B et al: [Malignant primary cardiac tumors in childhood and adolescence.] Arch Pediatr. 17(5):495-501, 2010
- O'Donnell DH et al: Cardiac tumors: optimal cardiac MR sequences and spectrum of imaging appearances. AJR Am J Roentgenol. 193(2):377-87, 2009
- Truong PT et al: Treatment and outcomes in adult patients with primary cardiac sarcoma: the British Columbia Cancer Agency experience. Ann Surg Oncol. 16(12):3358-65, 2009
- Murinello A et al: Cardiac angiosarcoma--a review. Rev Port Cardiol. 26(5):577-84, 2007
- Sparrow PJ et al: MR imaging of cardiac tumors. Radiographics. 25(5):1255-76, 2005
- Best AK et al: Best cases from the AFIP: cardiac angiosarcoma. Radiographics. 23 Spec No:S141-5, 2003
- Chiles C et al: Metastatic involvement of the heart and pericardium: CT and MR imaging. Radiographics. 21(2):439-49, 2001
- Araoz PA et al: CT and MR imaging of benign primary cardiac neoplasms with echocardiographic correlation. Radiographics. 20(5):1303-19, 2000
- Grebenc ML et al: Primary cardiac and pericardial neoplasms: radiologic-pathologic correlation. Radiographics. 20(4):1073-103; quiz 1110-1, 1112, 2000
