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Chest
Diagnosis
Cardiovascular Disorders
Cardiovascular Neoplasms
Cardiac Sarcoma
Cardiac Sarcoma
Brett W. Carter, MD, CPPS
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Pathology

          • Clinical Issues

            TERMINOLOGY

            • Definitions

              • Most common primary cardiac malignancy
              • Restricted to heart and pericardium

            IMAGING

            • General Features

              • Radiographic Findings

                • CT Findings

                  • MR Findings

                    • Imaging Recommendations

                      DIFFERENTIAL DIAGNOSIS

                        PATHOLOGY

                        • Staging, Grading, & Classification

                          • Gross Pathologic & Surgical Features

                            • Microscopic Features

                              CLINICAL ISSUES

                              • Presentation

                                • Demographics

                                  • Natural History & Prognosis

                                    • Treatment

                                      DIAGNOSTIC CHECKLIST

                                      • Consider

                                        Selected References

                                        1. Andersen KF et al: Primary cardiac intimal sarcoma visualized on 2-[18F]FDG PET/CT. Diagnostics (Basel). 10(9), 2020
                                        2. Sia CH et al: Cardiac sarcoma attached to pacemaker lead. J Card Surg. 35(5):1148-51, 2020
                                        3. Edquist M et al: Computed tomography imaging characteristics of primary atrial intimal sarcoma. Clin Imaging. 54:112-5, 2019
                                        4. Siontis BL et al: Primary cardiac sarcoma: a rare, aggressive malignancy with a high propensity for brain metastases. Sarcoma. 2019:1960593, 2019
                                        5. Yu JF et al: Clinical and imaging manifestations of primary cardiac angiosarcoma. BMC Med Imaging. 19(1):16, 2019
                                        6. Maleszewski JJ et al: Pathology, imaging, and treatment of cardiac tumours. Nat Rev Cardiol. 14(9):536-49, 2017
                                        7. Hoffmeier A et al: Cardiac tumors--diagnosis and surgical treatment. Dtsch Arztebl Int. 111(12):205-11, 2014
                                        8. Ostrowski S et al: Sarcomas of the heart as a difficult interdisciplinary problem. Arch Med Sci. 10(1):135-48, 2014
                                        9. Bruce CJ: Cardiac tumours: diagnosis and management. Heart. 97(2):151-60, 2011
                                        10. Sparrow PJ et al: MR imaging of cardiac tumors. Radiographics. 25(5):1255-76, 2005
                                        11. Grebenc ML et al: Primary cardiac and pericardial neoplasms: radiologic-pathologic correlation. Radiographics. 20(4):1073-103; quiz 1110-1, 1112, 2000
                                        Related Anatomy
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                                        Related Differential Diagnoses
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                                        References
                                        Tables

                                        Tables

                                        KEY FACTS

                                        • Terminology

                                          • Imaging

                                            • Top Differential Diagnoses

                                              • Pathology

                                                • Clinical Issues

                                                  TERMINOLOGY

                                                  • Definitions

                                                    • Most common primary cardiac malignancy
                                                    • Restricted to heart and pericardium

                                                  IMAGING

                                                  • General Features

                                                    • Radiographic Findings

                                                      • CT Findings

                                                        • MR Findings

                                                          • Imaging Recommendations

                                                            DIFFERENTIAL DIAGNOSIS

                                                              PATHOLOGY

                                                              • Staging, Grading, & Classification

                                                                • Gross Pathologic & Surgical Features

                                                                  • Microscopic Features

                                                                    CLINICAL ISSUES

                                                                    • Presentation

                                                                      • Demographics

                                                                        • Natural History & Prognosis

                                                                          • Treatment

                                                                            DIAGNOSTIC CHECKLIST

                                                                            • Consider

                                                                              Selected References

                                                                              1. Andersen KF et al: Primary cardiac intimal sarcoma visualized on 2-[18F]FDG PET/CT. Diagnostics (Basel). 10(9), 2020
                                                                              2. Sia CH et al: Cardiac sarcoma attached to pacemaker lead. J Card Surg. 35(5):1148-51, 2020
                                                                              3. Edquist M et al: Computed tomography imaging characteristics of primary atrial intimal sarcoma. Clin Imaging. 54:112-5, 2019
                                                                              4. Siontis BL et al: Primary cardiac sarcoma: a rare, aggressive malignancy with a high propensity for brain metastases. Sarcoma. 2019:1960593, 2019
                                                                              5. Yu JF et al: Clinical and imaging manifestations of primary cardiac angiosarcoma. BMC Med Imaging. 19(1):16, 2019
                                                                              6. Maleszewski JJ et al: Pathology, imaging, and treatment of cardiac tumours. Nat Rev Cardiol. 14(9):536-49, 2017
                                                                              7. Hoffmeier A et al: Cardiac tumors--diagnosis and surgical treatment. Dtsch Arztebl Int. 111(12):205-11, 2014
                                                                              8. Ostrowski S et al: Sarcomas of the heart as a difficult interdisciplinary problem. Arch Med Sci. 10(1):135-48, 2014
                                                                              9. Bruce CJ: Cardiac tumours: diagnosis and management. Heart. 97(2):151-60, 2011
                                                                              10. Sparrow PJ et al: MR imaging of cardiac tumors. Radiographics. 25(5):1255-76, 2005
                                                                              11. Grebenc ML et al: Primary cardiac and pericardial neoplasms: radiologic-pathologic correlation. Radiographics. 20(4):1073-103; quiz 1110-1, 1112, 2000