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Carotid Space Schwannoma
Karen L. Salzman, MD
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6

KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Pathology

          • Clinical Issues

            TERMINOLOGY

            • Synonyms

              • Neuroma, neurilemmoma
            • Definitions

              • Benign tumor of Schwann cells that wrap around cranial nerve in carotid space (CS)

            IMAGING

            • General Features

              • CT Findings

                • MR Findings

                  • Angiographic Findings

                    • Imaging Recommendations

                      DIFFERENTIAL DIAGNOSIS

                        PATHOLOGY

                        • General Features

                          • Gross Pathologic & Surgical Features

                            • Microscopic Features

                              CLINICAL ISSUES

                              • Presentation

                                • Demographics

                                  • Natural History & Prognosis

                                    • Treatment

                                      DIAGNOSTIC CHECKLIST

                                      • Consider

                                        • Image Interpretation Pearls

                                          Selected References

                                          1. Shinohara Y et al: Neurilemmoma of the Vagus Nerve in the Poststyloid Parapharyngeal Space. J Clin Diagn Res. 10(1):ZD17-9, 2016
                                          2. Cavallaro G et al: A literature review on surgery for cervical vagal schwannomas. World J Surg Oncol. 13:130, 2015
                                          3. Li SY et al: Minimally invasive endoscope-assisted trans-oral excision of huge parapharyngeal space tumors. Auris Nasus Larynx. 42(2):179-82, 2015
                                          4. Prasad SC et al: Lateral skull base approaches in the management of benign parapharyngeal space tumors. Auris Nasus Larynx. 42(3):189-98, 2015
                                          5. Yafit D et al: An algorithm for treating extracranial head and neck schwannomas. Eur Arch Otorhinolaryngol. 272(8):2035-8, 2015
                                          6. Kitazume Y et al: Diffusion-weighted magnetic resonance neurography for parapharyngeal schwannomas: preoperative determination of the originating nerves. J Comput Assist Tomogr. 38(6):930-5, 2014
                                          7. Amin MF et al: Diagnostic efficiency of multidetector computed tomography versus magnetic resonance imaging in differentiation of head and neck paragangliomas from other mimicking vascular lesions: comparison with histopathologic examination. Eur Arch Otorhinolaryngol. 270(3):1045-53, 2013
                                          8. Langerman A et al: Tumors of the cervical sympathetic chain--diagnosis and management. Head Neck. 35(7):930-3, 2013
                                          9. Casserly P et al: Cervical sympathetic chain schwannoma masquerading as a carotid body tumour with a postoperative complication of first-bite syndrome. Eur Arch Otorhinolaryngol. 266(10):1659-62, 2009
                                          10. Le Corroller T et al: Sonographic diagnosis of a cervical vagal schwannoma. J Clin Ultrasound. 37(1):57-60, 2009
                                          11. Nagamine WH et al: Glossopharyngeal schwannoma of the suprahyoid carotid space: case report and discussion of the relationship to the carotid artery. Laryngoscope. 119(4):653-6, 2009
                                          12. Schupp DJ et al: Schwannoma of the vagus nerve masquerading as a carotid body tumor. Vascular. 17(4):222-5, 2009
                                          13. Tomita T et al: Diagnosis and management of cervical sympathetic chain schwannoma: a review of 9 cases. Acta Otolaryngol. 129(3):324-9, 2009
                                          14. Warman M et al: Radiology quiz case. Cervical sympathetic schwannoma. Arch Otolaryngol Head Neck Surg. 134(7):781-2, 2008
                                          15. Saito DM et al: Parapharyngeal space schwannomas: preoperative imaging determination of the nerve of origin. Arch Otolaryngol Head Neck Surg. 133(7):662-7, 2007
                                          16. Wang CP et al: Splaying of the carotid bifurcation caused by a cervical sympathetic chain schwannoma. Ann Otol Rhinol Laryngol. 113(9):696-9, 2004
                                          17. Wax MK et al: Cervical sympathetic chain schwannoma. Laryngoscope. 114(12):2210-3, 2004
                                          18. Gallo A et al: Recurrent malignant schwannoma of the parapharyngeal space in neurofibromatosis type 1. Ear Nose Throat J. 82(11):862-5, 2003
                                          19. Pang KP et al: Parapharyngeal space tumours: an 18 year review. J Laryngol Otol. 116(3):170-5, 2002
                                          20. Colreavy MP et al: Head and neck schwannomas--a 10 year review. J Laryngol Otol. 114(2):119-24, 2000
                                          21. Eldevik OP et al: Imaging findings in schwannomas of the jugular foramen. AJNR Am J Neuroradiol. 21(6):1139-44, 2000
                                          22. al-Otieschan AA et al: Malignant schwannoma of the parapharyngeal space. J Laryngol Otol. 112(9):883-7, 1998
                                          23. Som PM et al: Lesions of the parapharyngeal space. Role of MR imaging. Otolaryngol Clin North Am. 28(3):515-42, 1995
                                          24. Silver AJ et al: Computed tomography of the carotid space and related cervical spaces. Part II: Neurogenic tumors. Radiology. 150(3):729-35, 1984
                                          Related Anatomy
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                                          Related Differential Diagnoses
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                                          References
                                          Tables

                                          Tables

                                          KEY FACTS

                                          • Terminology

                                            • Imaging

                                              • Top Differential Diagnoses

                                                • Pathology

                                                  • Clinical Issues

                                                    TERMINOLOGY

                                                    • Synonyms

                                                      • Neuroma, neurilemmoma
                                                    • Definitions

                                                      • Benign tumor of Schwann cells that wrap around cranial nerve in carotid space (CS)

                                                    IMAGING

                                                    • General Features

                                                      • CT Findings

                                                        • MR Findings

                                                          • Angiographic Findings

                                                            • Imaging Recommendations

                                                              DIFFERENTIAL DIAGNOSIS

                                                                PATHOLOGY

                                                                • General Features

                                                                  • Gross Pathologic & Surgical Features

                                                                    • Microscopic Features

                                                                      CLINICAL ISSUES

                                                                      • Presentation

                                                                        • Demographics

                                                                          • Natural History & Prognosis

                                                                            • Treatment

                                                                              DIAGNOSTIC CHECKLIST

                                                                              • Consider

                                                                                • Image Interpretation Pearls

                                                                                  Selected References

                                                                                  1. Shinohara Y et al: Neurilemmoma of the Vagus Nerve in the Poststyloid Parapharyngeal Space. J Clin Diagn Res. 10(1):ZD17-9, 2016
                                                                                  2. Cavallaro G et al: A literature review on surgery for cervical vagal schwannomas. World J Surg Oncol. 13:130, 2015
                                                                                  3. Li SY et al: Minimally invasive endoscope-assisted trans-oral excision of huge parapharyngeal space tumors. Auris Nasus Larynx. 42(2):179-82, 2015
                                                                                  4. Prasad SC et al: Lateral skull base approaches in the management of benign parapharyngeal space tumors. Auris Nasus Larynx. 42(3):189-98, 2015
                                                                                  5. Yafit D et al: An algorithm for treating extracranial head and neck schwannomas. Eur Arch Otorhinolaryngol. 272(8):2035-8, 2015
                                                                                  6. Kitazume Y et al: Diffusion-weighted magnetic resonance neurography for parapharyngeal schwannomas: preoperative determination of the originating nerves. J Comput Assist Tomogr. 38(6):930-5, 2014
                                                                                  7. Amin MF et al: Diagnostic efficiency of multidetector computed tomography versus magnetic resonance imaging in differentiation of head and neck paragangliomas from other mimicking vascular lesions: comparison with histopathologic examination. Eur Arch Otorhinolaryngol. 270(3):1045-53, 2013
                                                                                  8. Langerman A et al: Tumors of the cervical sympathetic chain--diagnosis and management. Head Neck. 35(7):930-3, 2013
                                                                                  9. Casserly P et al: Cervical sympathetic chain schwannoma masquerading as a carotid body tumour with a postoperative complication of first-bite syndrome. Eur Arch Otorhinolaryngol. 266(10):1659-62, 2009
                                                                                  10. Le Corroller T et al: Sonographic diagnosis of a cervical vagal schwannoma. J Clin Ultrasound. 37(1):57-60, 2009
                                                                                  11. Nagamine WH et al: Glossopharyngeal schwannoma of the suprahyoid carotid space: case report and discussion of the relationship to the carotid artery. Laryngoscope. 119(4):653-6, 2009
                                                                                  12. Schupp DJ et al: Schwannoma of the vagus nerve masquerading as a carotid body tumor. Vascular. 17(4):222-5, 2009
                                                                                  13. Tomita T et al: Diagnosis and management of cervical sympathetic chain schwannoma: a review of 9 cases. Acta Otolaryngol. 129(3):324-9, 2009
                                                                                  14. Warman M et al: Radiology quiz case. Cervical sympathetic schwannoma. Arch Otolaryngol Head Neck Surg. 134(7):781-2, 2008
                                                                                  15. Saito DM et al: Parapharyngeal space schwannomas: preoperative imaging determination of the nerve of origin. Arch Otolaryngol Head Neck Surg. 133(7):662-7, 2007
                                                                                  16. Wang CP et al: Splaying of the carotid bifurcation caused by a cervical sympathetic chain schwannoma. Ann Otol Rhinol Laryngol. 113(9):696-9, 2004
                                                                                  17. Wax MK et al: Cervical sympathetic chain schwannoma. Laryngoscope. 114(12):2210-3, 2004
                                                                                  18. Gallo A et al: Recurrent malignant schwannoma of the parapharyngeal space in neurofibromatosis type 1. Ear Nose Throat J. 82(11):862-5, 2003
                                                                                  19. Pang KP et al: Parapharyngeal space tumours: an 18 year review. J Laryngol Otol. 116(3):170-5, 2002
                                                                                  20. Colreavy MP et al: Head and neck schwannomas--a 10 year review. J Laryngol Otol. 114(2):119-24, 2000
                                                                                  21. Eldevik OP et al: Imaging findings in schwannomas of the jugular foramen. AJNR Am J Neuroradiol. 21(6):1139-44, 2000
                                                                                  22. al-Otieschan AA et al: Malignant schwannoma of the parapharyngeal space. J Laryngol Otol. 112(9):883-7, 1998
                                                                                  23. Som PM et al: Lesions of the parapharyngeal space. Role of MR imaging. Otolaryngol Clin North Am. 28(3):515-42, 1995
                                                                                  24. Silver AJ et al: Computed tomography of the carotid space and related cervical spaces. Part II: Neurogenic tumors. Radiology. 150(3):729-35, 1984