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Castleman Disease
Eunice Y. L. Dai, MBBS, FRCR; Yolanda Y. P. Lee, MBChB, FRCR; Anil T. Ahuja, MD, FRCR
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Pathology

          • Clinical Issues

            • Diagnostic Checklist

              TERMINOLOGY

              • Abbreviations

                • Castleman disease (CD), unicentric CD (UCD), multicentric CD (MCD)
              • Definitions

                • Rare, benign lymphoproliferative disorder of uncertain cause characterized by distinctive pattern of hypervascular lymphoid hyperplasia

              IMAGING

              • General Features

                • Ultrasonographic Findings

                  • CT Findings

                    • MR Findings

                      DIFFERENTIAL DIAGNOSIS

                        PATHOLOGY

                        • General Features

                          • Microscopic Features

                            CLINICAL ISSUES

                            • Presentation

                              • Demographics

                                • Natural History & Prognosis

                                  • Treatment

                                    DIAGNOSTIC CHECKLIST

                                    • Image Interpretation Pearls

                                      Selected References

                                      1. Jiang XH et al: Castleman disease of the neck: CT and MR imaging findings. Eur J Radiol. 83(11):2041-50, 2014
                                      2. Puram SV et al: Castleman disease presenting in the neck: report of a case and review of the literature. Am J Otolaryngol. 34(3):239-44, 2013
                                      3. Mahmood N et al: Ultrasound and Doppler findings in a rare case of Castleman's disease of the parotid. Dentomaxillofac Radiol. 39(1):54-6, 2010
                                      4. Wen L et al: CT characteristics of cervical Castleman's disease. Clin Imaging. 29(2):141-3, 2005
                                      5. Yildirim H et al: Castleman's disease with isolated extensive cervical involvement. Australas Radiol. 49(2):132-5, 2005
                                      6. Sanchez-Cuellar A et al: Castleman disease (giant lymph node hyperplasia) in the maxillofacial region: a report of 3 cases. J Oral Maxillofac Surg. 59(2):228-31, 2001
                                      7. Poyanli A et al: Cervical Castleman's disease: imaging findings. Eur Radiol. 10(7):1190-2, 2000
                                      8. Ahuja AT et al: Ultrasound appearance of parotid Castleman's disease. J Clin Ultrasound. 23(4):254-8, 1995
                                      Related Anatomy
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                                      Related Differential Diagnoses
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                                      References
                                      Tables

                                      Tables

                                      KEY FACTS

                                      • Terminology

                                        • Imaging

                                          • Top Differential Diagnoses

                                            • Pathology

                                              • Clinical Issues

                                                • Diagnostic Checklist

                                                  TERMINOLOGY

                                                  • Abbreviations

                                                    • Castleman disease (CD), unicentric CD (UCD), multicentric CD (MCD)
                                                  • Definitions

                                                    • Rare, benign lymphoproliferative disorder of uncertain cause characterized by distinctive pattern of hypervascular lymphoid hyperplasia

                                                  IMAGING

                                                  • General Features

                                                    • Ultrasonographic Findings

                                                      • CT Findings

                                                        • MR Findings

                                                          DIFFERENTIAL DIAGNOSIS

                                                            PATHOLOGY

                                                            • General Features

                                                              • Microscopic Features

                                                                CLINICAL ISSUES

                                                                • Presentation

                                                                  • Demographics

                                                                    • Natural History & Prognosis

                                                                      • Treatment

                                                                        DIAGNOSTIC CHECKLIST

                                                                        • Image Interpretation Pearls

                                                                          Selected References

                                                                          1. Jiang XH et al: Castleman disease of the neck: CT and MR imaging findings. Eur J Radiol. 83(11):2041-50, 2014
                                                                          2. Puram SV et al: Castleman disease presenting in the neck: report of a case and review of the literature. Am J Otolaryngol. 34(3):239-44, 2013
                                                                          3. Mahmood N et al: Ultrasound and Doppler findings in a rare case of Castleman's disease of the parotid. Dentomaxillofac Radiol. 39(1):54-6, 2010
                                                                          4. Wen L et al: CT characteristics of cervical Castleman's disease. Clin Imaging. 29(2):141-3, 2005
                                                                          5. Yildirim H et al: Castleman's disease with isolated extensive cervical involvement. Australas Radiol. 49(2):132-5, 2005
                                                                          6. Sanchez-Cuellar A et al: Castleman disease (giant lymph node hyperplasia) in the maxillofacial region: a report of 3 cases. J Oral Maxillofac Surg. 59(2):228-31, 2001
                                                                          7. Poyanli A et al: Cervical Castleman's disease: imaging findings. Eur Radiol. 10(7):1190-2, 2000
                                                                          8. Ahuja AT et al: Ultrasound appearance of parotid Castleman's disease. J Clin Ultrasound. 23(4):254-8, 1995