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Castleman Disease
Ethan A. Smith, MD
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Pathology

          • Clinical Issues

            TERMINOLOGY

            • Synonyms

              • Angiofollicular lymph node hyperplasia
            • Definitions

              • Benign lymphoproliferative disorder
                • Can be unicentric (most common) or multicentric/systemic

            IMAGING

            • General Features

              • Radiographic Findings

                • CT Findings

                  • MR Findings

                    • Ultrasonographic Findings

                      • Nuclear Medicine Findings

                        • Imaging Recommendations

                          DIFFERENTIAL DIAGNOSIS

                            PATHOLOGY

                            • General Features

                              • Staging, Grading, & Classification

                                • Microscopic Features

                                  CLINICAL ISSUES

                                  • Presentation

                                    • Demographics

                                      • Natural History & Prognosis

                                        Selected References

                                        1. Chung EM et al: Solid tumors of the peritoneum, omentum, and mesentery in children: radiologic-pathologic correlation: from the radiologic pathology archives. Radiographics. 35(2):521-46, 2015
                                        2. Madan R et al: The spectrum of Castleman's disease: mimics, radiologic pathologic correlation and role of imaging in patient management. Eur J Radiol. 81(1):123-31, 2012
                                        3. Muskardin TW et al: Castleman disease and associated autoimmune disease. Curr Opin Rheumatol. 24(1):76-83, 2012
                                        4. Dham A et al: Castleman disease. Curr Opin Hematol. 14(4):354-9, 2007
                                        5. Ko SF et al: Imaging spectrum of Castleman's disease. AJR Am J Roentgenol. 182(3):769-75, 2004
                                        6. Germaine LM et al: Castleman's disease. Clin Imaging. 27(6):431-4, 2003
                                        7. Kim TJ et al: Castleman disease of the abdomen: imaging spectrum and clinicopathologic correlations. J Comput Assist Tomogr. 25(2):207-14, 2001
                                        8. Parez N et al: Paediatric Castleman disease: report of seven cases and review of the literature. Eur J Pediatr. 158(8):631-7, 1999
                                        Related Anatomy
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                                        Related Differential Diagnoses
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                                        References
                                        Tables

                                        Tables

                                        KEY FACTS

                                        • Terminology

                                          • Imaging

                                            • Top Differential Diagnoses

                                              • Pathology

                                                • Clinical Issues

                                                  TERMINOLOGY

                                                  • Synonyms

                                                    • Angiofollicular lymph node hyperplasia
                                                  • Definitions

                                                    • Benign lymphoproliferative disorder
                                                      • Can be unicentric (most common) or multicentric/systemic

                                                  IMAGING

                                                  • General Features

                                                    • Radiographic Findings

                                                      • CT Findings

                                                        • MR Findings

                                                          • Ultrasonographic Findings

                                                            • Nuclear Medicine Findings

                                                              • Imaging Recommendations

                                                                DIFFERENTIAL DIAGNOSIS

                                                                  PATHOLOGY

                                                                  • General Features

                                                                    • Staging, Grading, & Classification

                                                                      • Microscopic Features

                                                                        CLINICAL ISSUES

                                                                        • Presentation

                                                                          • Demographics

                                                                            • Natural History & Prognosis

                                                                              Selected References

                                                                              1. Chung EM et al: Solid tumors of the peritoneum, omentum, and mesentery in children: radiologic-pathologic correlation: from the radiologic pathology archives. Radiographics. 35(2):521-46, 2015
                                                                              2. Madan R et al: The spectrum of Castleman's disease: mimics, radiologic pathologic correlation and role of imaging in patient management. Eur J Radiol. 81(1):123-31, 2012
                                                                              3. Muskardin TW et al: Castleman disease and associated autoimmune disease. Curr Opin Rheumatol. 24(1):76-83, 2012
                                                                              4. Dham A et al: Castleman disease. Curr Opin Hematol. 14(4):354-9, 2007
                                                                              5. Ko SF et al: Imaging spectrum of Castleman's disease. AJR Am J Roentgenol. 182(3):769-75, 2004
                                                                              6. Germaine LM et al: Castleman's disease. Clin Imaging. 27(6):431-4, 2003
                                                                              7. Kim TJ et al: Castleman disease of the abdomen: imaging spectrum and clinicopathologic correlations. J Comput Assist Tomogr. 25(2):207-14, 2001
                                                                              8. Parez N et al: Paediatric Castleman disease: report of seven cases and review of the literature. Eur J Pediatr. 158(8):631-7, 1999