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Cat-Scratch Disease
A. Carlson Merrow, Jr., MD, FAAP
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Clinical Issues

          • Diagnostic Checklist

            TERMINOLOGY

            • Abbreviations

              • Cat-scratch disease (CSD)
            • Definitions

              • Spectrum of clinical manifestations resulting from Bartonella henselae inoculation of skin by cat scratch or bite
                • Most common clinical presentation ("typical CSD")
                  • Tender regional adenopathy + fever 1-3 weeks after inoculation; papule at scratch site may be 1st clue
                • Self-limited in most patients
                  • Disseminated disease in 5-14%

            IMAGING

            • General Features

              • Imaging Recommendations

                DIFFERENTIAL DIAGNOSIS

                  PATHOLOGY

                  • General Features

                    • Microscopic Features

                      CLINICAL ISSUES

                      • Presentation

                        • Demographics

                          • Natural History & Prognosis

                            • Treatment

                              DIAGNOSTIC CHECKLIST

                              • Image Interpretation Pearls

                                Selected References

                                1. Chang CC et al: Disseminated cat-scratch disease: case report and review of the literature. Paediatr Int Child Health. [epub ahead of print], 2015
                                2. Kraft KE et al: Hepatosplenic cat-scratch disease in children and the positive contribution of 18F-FDG imaging. Clin Nucl Med. 40(9):746-7, 2015
                                3. Melville DM et al: Sonography of cat scratch disease. J Ultrasound Med. 34(3):387-94, 2015
                                4. Rohr A et al: Spectrum of radiological manifestations of paediatric cat-scratch disease. Pediatr Radiol. 42(11):1380-4, 2012
                                5. Klotz SA et al: Cat-scratch disease. Am Fam Physician. 83(2):152-5, 2011
                                6. Florin TA et al: Beyond cat scratch disease: widening spectrum of Bartonella henselae infection. Pediatrics. 121(5):e1413-25, 2008
                                7. Scolfaro C et al: Prolonged follow up of seven patients affected by hepatosplenic granulomata due to cat-scratch disease. Eur J Pediatr. 167(4):471-3, 2008
                                8. Massei F et al: The expanded spectrum of bartonellosis in children. Infect Dis Clin North Am. 19(3):691-711, 2005
                                Related Anatomy
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                                Related Differential Diagnoses
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                                References
                                Tables

                                Tables

                                KEY FACTS

                                • Terminology

                                  • Imaging

                                    • Top Differential Diagnoses

                                      • Clinical Issues

                                        • Diagnostic Checklist

                                          TERMINOLOGY

                                          • Abbreviations

                                            • Cat-scratch disease (CSD)
                                          • Definitions

                                            • Spectrum of clinical manifestations resulting from Bartonella henselae inoculation of skin by cat scratch or bite
                                              • Most common clinical presentation ("typical CSD")
                                                • Tender regional adenopathy + fever 1-3 weeks after inoculation; papule at scratch site may be 1st clue
                                              • Self-limited in most patients
                                                • Disseminated disease in 5-14%

                                          IMAGING

                                          • General Features

                                            • Imaging Recommendations

                                              DIFFERENTIAL DIAGNOSIS

                                                PATHOLOGY

                                                • General Features

                                                  • Microscopic Features

                                                    CLINICAL ISSUES

                                                    • Presentation

                                                      • Demographics

                                                        • Natural History & Prognosis

                                                          • Treatment

                                                            DIAGNOSTIC CHECKLIST

                                                            • Image Interpretation Pearls

                                                              Selected References

                                                              1. Chang CC et al: Disseminated cat-scratch disease: case report and review of the literature. Paediatr Int Child Health. [epub ahead of print], 2015
                                                              2. Kraft KE et al: Hepatosplenic cat-scratch disease in children and the positive contribution of 18F-FDG imaging. Clin Nucl Med. 40(9):746-7, 2015
                                                              3. Melville DM et al: Sonography of cat scratch disease. J Ultrasound Med. 34(3):387-94, 2015
                                                              4. Rohr A et al: Spectrum of radiological manifestations of paediatric cat-scratch disease. Pediatr Radiol. 42(11):1380-4, 2012
                                                              5. Klotz SA et al: Cat-scratch disease. Am Fam Physician. 83(2):152-5, 2011
                                                              6. Florin TA et al: Beyond cat scratch disease: widening spectrum of Bartonella henselae infection. Pediatrics. 121(5):e1413-25, 2008
                                                              7. Scolfaro C et al: Prolonged follow up of seven patients affected by hepatosplenic granulomata due to cat-scratch disease. Eur J Pediatr. 167(4):471-3, 2008
                                                              8. Massei F et al: The expanded spectrum of bartonellosis in children. Infect Dis Clin North Am. 19(3):691-711, 2005