Cat-scratch disease (CSD): Spectrum of clinical manifestations resulting from Bartonella henselae inoculation of skin by cat scratch
"Typical CSD" (most common clinical presentation): Tender regional adenopathy + fever 1-3 weeks after inoculation
Papule at scratch site may be 1st clue
Self-limited in most patients
Disseminated disease in 5-14%
IMAGING
General Features
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Image Interpretation Pearls
Selected References
Landes M et al: Cat scratch disease presenting as fever of unknown origin is a unique clinical syndrome. Clin Infect Dis. 71(11):2818-24, 2020
Cheslock MA et al: Human bartonellosis: an underappreciated public health problem? Trop Med Infect Dis. 4(2), 2019
Ksiaa I et al: Update on Bartonella neuroretinitis. J Curr Ophthalmol. 31(3):254-61, 2019
Chang CC et al: Disseminated cat-scratch disease: case report and review of the literature. Paediatr Int Child Health. 36(3):232-4, 2015
Kraft KE et al: Hepatosplenic cat-scratch disease in children and the positive contribution of 18F-FDG imaging. Clin Nucl Med. 40(9):746-7, 2015
Mazur-Melewska K et al: Cat-scratch disease: a wide spectrum of clinical pictures. Postepy Dermatol Alergol. 32(3):216-20, 2015
Melville DM et al: Sonography of cat scratch disease. J Ultrasound Med. 34(3):387-94, 2015
Rohr A et al: Spectrum of radiological manifestations of paediatric cat-scratch disease. Pediatr Radiol. 42(11):1380-4, 2012
Klotz SA et al: Cat-scratch disease. Am Fam Physician. 83(2):152-5, 2011
Florin TA et al: Beyond cat scratch disease: widening spectrum of Bartonella henselae infection. Pediatrics. 121(5):e1413-25, 2008
Scolfaro C et al: Prolonged follow up of seven patients affected by hepatosplenic granulomata due to cat-scratch disease. Eur J Pediatr. 167(4):471-3, 2008
Massei F et al: The expanded spectrum of bartonellosis in children. Infect Dis Clin North Am. 19(3):691-711, 2005
Related Anatomy
Loading...
Related Differential Diagnoses
Loading...
References
Tables
Tables
KEY FACTS
Terminology
Imaging
Top Differential Diagnoses
Clinical Issues
Diagnostic Checklist
TERMINOLOGY
Definitions
Cat-scratch disease (CSD): Spectrum of clinical manifestations resulting from Bartonella henselae inoculation of skin by cat scratch
"Typical CSD" (most common clinical presentation): Tender regional adenopathy + fever 1-3 weeks after inoculation
Papule at scratch site may be 1st clue
Self-limited in most patients
Disseminated disease in 5-14%
IMAGING
General Features
Imaging Recommendations
DIFFERENTIAL DIAGNOSIS
PATHOLOGY
General Features
Microscopic Features
CLINICAL ISSUES
Presentation
Demographics
Natural History & Prognosis
Treatment
DIAGNOSTIC CHECKLIST
Image Interpretation Pearls
Selected References
Landes M et al: Cat scratch disease presenting as fever of unknown origin is a unique clinical syndrome. Clin Infect Dis. 71(11):2818-24, 2020
Cheslock MA et al: Human bartonellosis: an underappreciated public health problem? Trop Med Infect Dis. 4(2), 2019
Ksiaa I et al: Update on Bartonella neuroretinitis. J Curr Ophthalmol. 31(3):254-61, 2019
Chang CC et al: Disseminated cat-scratch disease: case report and review of the literature. Paediatr Int Child Health. 36(3):232-4, 2015
Kraft KE et al: Hepatosplenic cat-scratch disease in children and the positive contribution of 18F-FDG imaging. Clin Nucl Med. 40(9):746-7, 2015
Mazur-Melewska K et al: Cat-scratch disease: a wide spectrum of clinical pictures. Postepy Dermatol Alergol. 32(3):216-20, 2015
Melville DM et al: Sonography of cat scratch disease. J Ultrasound Med. 34(3):387-94, 2015
Rohr A et al: Spectrum of radiological manifestations of paediatric cat-scratch disease. Pediatr Radiol. 42(11):1380-4, 2012
Klotz SA et al: Cat-scratch disease. Am Fam Physician. 83(2):152-5, 2011
Florin TA et al: Beyond cat scratch disease: widening spectrum of Bartonella henselae infection. Pediatrics. 121(5):e1413-25, 2008
Scolfaro C et al: Prolonged follow up of seven patients affected by hepatosplenic granulomata due to cat-scratch disease. Eur J Pediatr. 167(4):471-3, 2008
Massei F et al: The expanded spectrum of bartonellosis in children. Infect Dis Clin North Am. 19(3):691-711, 2005
STATdx includes over 200,000 searchable images, including x-ray, CT, MR, and ultrasound images. To access all images, please log in or subscribe.