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Cavum Septum Pellucidum
Usha D. Nagaraj, MD
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KEY FACTS

  • Terminology

    • Imaging

      • Top Differential Diagnoses

        • Clinical Issues

          • Diagnostic Checklist

            TERMINOLOGY

            • Abbreviations

              • Cavum septi pellucidi (CSP)
              • Cavum vergae (CV)
            • Definitions

              • Visible CSF space between leaves of cavum septi pellucidi (CSP); additional posterior continuation = CV
              • Referred to as septum pellucidum (SP) when/if leaves of CSP fuse to form single structure

            IMAGING

            • General Features

              • CT Findings

                • MR Findings

                  • Ultrasonographic Findings

                    DIFFERENTIAL DIAGNOSIS

                      PATHOLOGY

                      • General Features

                        • Staging, Grading, & Classification

                          CLINICAL ISSUES

                          • Presentation

                            • Demographics

                              • Natural History & Prognosis

                                • Treatment

                                  DIAGNOSTIC CHECKLIST

                                  • Image Interpretation Pearls

                                    Selected References

                                    1. Kertes I et al: The normal fetal cavum septum pellucidum in MR imaging - new biometric data. Eur J Radiol. 135:109470, 2021
                                    2. Nagaraj UD et al: Abnormalities associated with the cavum septi pellucidi on fetal MRI: what radiologists need to know. AJR Am J Roentgenol. 210(5):989-97, 2018
                                    3. Gardner RC et al: Cavum septum pellucidum in retired American pro-football players. J Neurotrauma. 33(1):157-61, 2016
                                    4. Toivonen P et al: Cavum septum pellucidum and psychopathy. Br J Psychiatry. 203(2):152-3, 2013
                                    5. Santo S et al: Counseling in fetal medicine: agenesis of the corpus callosum. Ultrasound Obstet Gynecol. 40(5):513-21, 2012
                                    6. Winter TC et al: The cavum septi pellucidi: why is it important? J Ultrasound Med. 29(3):427-44, 2010
                                    7. Callen PW et al: Columns of the fornix, not to be mistaken for the cavum septi pellucidi on prenatal sonography. J Ultrasound Med. 27(1):25-31, 2008
                                    8. Takahashi T et al: Prevalence of large cavum septi pellucidi in ultra high-risk individuals and patients with psychotic disorders. Schizophr Res. 105(1-3):236-44, 2008
                                    9. Needelman H et al: Postterm closure of the cavum septi pellucidi and developmental outcome in premature infants. J Child Neurol. 22(3):314-6, 2007
                                    10. Epelman M et al: Differential diagnosis of intracranial cystic lesions at head US: correlation with CT and MR imaging. Radiographics. 26(1):173-96, 2006
                                    11. Sencer A et al: Cerebrospinal fluid dynamics of the cava septi pellucidi and vergae. Case report. J Neurosurg. 94(1):127-9, 2001
                                    Related Anatomy
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                                    Related Differential Diagnoses
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                                    References
                                    Tables

                                    Tables

                                    KEY FACTS

                                    • Terminology

                                      • Imaging

                                        • Top Differential Diagnoses

                                          • Clinical Issues

                                            • Diagnostic Checklist

                                              TERMINOLOGY

                                              • Abbreviations

                                                • Cavum septi pellucidi (CSP)
                                                • Cavum vergae (CV)
                                              • Definitions

                                                • Visible CSF space between leaves of cavum septi pellucidi (CSP); additional posterior continuation = CV
                                                • Referred to as septum pellucidum (SP) when/if leaves of CSP fuse to form single structure

                                              IMAGING

                                              • General Features

                                                • CT Findings

                                                  • MR Findings

                                                    • Ultrasonographic Findings

                                                      DIFFERENTIAL DIAGNOSIS

                                                        PATHOLOGY

                                                        • General Features

                                                          • Staging, Grading, & Classification

                                                            CLINICAL ISSUES

                                                            • Presentation

                                                              • Demographics

                                                                • Natural History & Prognosis

                                                                  • Treatment

                                                                    DIAGNOSTIC CHECKLIST

                                                                    • Image Interpretation Pearls

                                                                      Selected References

                                                                      1. Kertes I et al: The normal fetal cavum septum pellucidum in MR imaging - new biometric data. Eur J Radiol. 135:109470, 2021
                                                                      2. Nagaraj UD et al: Abnormalities associated with the cavum septi pellucidi on fetal MRI: what radiologists need to know. AJR Am J Roentgenol. 210(5):989-97, 2018
                                                                      3. Gardner RC et al: Cavum septum pellucidum in retired American pro-football players. J Neurotrauma. 33(1):157-61, 2016
                                                                      4. Toivonen P et al: Cavum septum pellucidum and psychopathy. Br J Psychiatry. 203(2):152-3, 2013
                                                                      5. Santo S et al: Counseling in fetal medicine: agenesis of the corpus callosum. Ultrasound Obstet Gynecol. 40(5):513-21, 2012
                                                                      6. Winter TC et al: The cavum septi pellucidi: why is it important? J Ultrasound Med. 29(3):427-44, 2010
                                                                      7. Callen PW et al: Columns of the fornix, not to be mistaken for the cavum septi pellucidi on prenatal sonography. J Ultrasound Med. 27(1):25-31, 2008
                                                                      8. Takahashi T et al: Prevalence of large cavum septi pellucidi in ultra high-risk individuals and patients with psychotic disorders. Schizophr Res. 105(1-3):236-44, 2008
                                                                      9. Needelman H et al: Postterm closure of the cavum septi pellucidi and developmental outcome in premature infants. J Child Neurol. 22(3):314-6, 2007
                                                                      10. Epelman M et al: Differential diagnosis of intracranial cystic lesions at head US: correlation with CT and MR imaging. Radiographics. 26(1):173-96, 2006
                                                                      11. Sencer A et al: Cerebrospinal fluid dynamics of the cava septi pellucidi and vergae. Case report. J Neurosurg. 94(1):127-9, 2001